Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1

EMBO Journal

Volumn 20, Issue 7, 2001, Pages 1715-1725

  Malik, Talat H ^a,b   Shoichet, Sarah A ^a,b   Latham, Peter ^a,b   Kroll, Todd G ^b   Peters, Luanne L ^c   Shivdasani, Ramesh A ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c JACKSON LABORATORY   (United States)

Author keywords

GATA proteins; Mammalian development; Transcriptional repression; Tricho rhino phalangeal syndromes; TRPS1

Indexed keywords

PROTEIN TRPS1; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CHONDRODYSPLASIA; CONTROLLED STUDY; EMBRYO; GENE FUNCTION; GENE ISOLATION; GENE MUTATION; GENE REPRESSION; GENETIC CONSERVATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; SEQUENCE ANALYSIS; TRANSCRIPTION REGULATION; XENOPUS;

ALGAL PROTEINS; AMINO ACID SEQUENCE; ANIMALS; CERCOPITHECUS AETHIOPS; CHROMOSOME MAPPING; COS CELLS; DNA-BINDING PROTEINS; GATA4 TRANSCRIPTION FACTOR; HUMANS; IKAROS TRANSCRIPTION FACTOR; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEAR PROTEINS; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; XENOPUS LAEVIS; XENOPUS PROTEINS; ZINC FINGERS;

ANIMALIA; INVERTEBRATA; MAMMALIA; VERTEBRATA;

EID: 0035794663     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.7.1715     Document Type: Article

References (49)

1. u-shaped encodes a zinc finger protein that regulates the proneural genes achaete and scute during the formation of bristles in Drosophila
2. CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling
3. FOG acts as a repressor of red blood cell development in Xenopus
4. The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine
5. The role of the Ikaros gene in lymphocyte development and homeostasis
6. Transcriptional activity of pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila
7. Mixer, a homeobox gene required for endoderm development
8. hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation
9. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes
10. DNA-binding specificities of the GATA transcription factor family
11. Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes
12. The transcription factor GATA6 is essential for early extraembryonic development
13. PAX8-PPARγ1 fusion oncogene in human thyroid carcinoma
14. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
15. The tricho-rhino-phalangeal syndrome with exostoses (or Langer-Giedion syndrome): Four additional patients without mental retardation and review of the literature
16. GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut
17. Genotypic and phenotypic spectrum in tricho-rhino-phalangeal syndrome types I and III
18. Structure and expression of a novel Frizzled gene isolated from the developing mouse gut
19. Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1
20. Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins
21. DNA-binding specificity of GATA family transcription factors
22. The zinc finger-containing transcription factors GATA-4, -5 and -6. Ubiquitously expressed regulators of tissue-specific gene expression
23. Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis
24. Mutations in a new gene, encoding a zinc-finger protein, cause tricho-rhino-phalangeal syndrome type I
25. NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1
26. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
27. Gata5 is required for the development of the heart and endoderm in zebrafish
28. The gene serpent has homeotic properties and specifies endoderm versus ectoderm within the Drosophila gut
29. Maps from two interspecific backcross DNA panels available as a community genetic mapping resource
30. Thyroid hormone-dependent regulation of the intestinal fatty acid-binding protein gene during amphibian metamorphosis
31. The transcriptional control of hematopoiesis
32. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development
33. Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector
34. Action of the Caenorhabditis elegans GATA factor END-1 in Xenopus suggests that similar mechanisms initiate endoderm development in ecdysozoa and vertebrates
35. Molecular cloning of FOG-2: A modulator of transcription factor GATA-4 in cardiomyocytes
36. A functionally conserved N-terminal domain of the Friend of GATA-2 (FOG-2) protein represses GATA4-dependent transcription
37. A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding fog-2
38. FOG-2: A novel GATA-family cofactor related to multitype zinc-finger proteins Friend of GATA-1 and U-shaped
39. FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium
40. Transcription factor GATA-3 is required for development of the T-cell lineage
41. An early haematopoietic defect in mice lacking the transcription factor GATA-2
42. FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation
43. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG
44. Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate
45. A role for GATA5 in Xenopus endoderm specification
46. Distinct roles for the two cGATA-1 finger domains
47. Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1
48. end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos