Medium-chain fatty acids stimulate interleukin-8 production in Caco-2 cells with different mechanisms from long-chain fatty acids

Journal of Gastroenterology and Hepatology (Australia)

Volumn 16, Issue 7, 2001, Pages 748-754

  Tanaka, Seigou ^a   Saitoh, Osamu ^a   Tabata, Kazue ^b   Matsuse, Ryoichi ^b   Kojima, Keishi ^a   Sugi, Kazunori ^a   Nakagawa, Ken ^a   Kayazawa, Masanobu ^a   Teranishi, Tsutomu ^a   Uchida, Kazuo ^b   Hirata, Ichiro ^a   Katsu, Ken Ichi ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b Kyoto Medical Science Laboratory   (Japan)

Author keywords

Fatty acids; Human intestinal epithelial cell line; Interleukin 8; Protein kinase C

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CALPHOSTIN C; DECANOIC ACID; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; INTERLEUKIN 8; LONG CHAIN FATTY ACID; MEDIUM CHAIN FATTY ACID; MESSENGER RNA; OLEIC ACID; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE INHIBITOR;

ARTICLE; CELL CULTURE; CELL STRAIN CACO 2; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENTERITIS; EPITHELIUM CELL; FAT INTAKE; GENE EXPRESSION; HUMAN; HUMAN CELL; INTESTINE CELL; PRIORITY JOURNAL;

EID: 0035720741     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1746.2001.02537.x     Document Type: Article

References (39)

1. Controlled trial of polymeric versus elemental diet in treatment of active Crohn's disease
2. Elemental diet as primary treatment of acute Crohn's disease
3. Modulation of intestinal immune system by dietary fat intake: Relevance to Crohn's disease
4. Effect of intravenous and intraduodenal fat on jejunal motility and on plasma cholecystokinin in man
5. Enhanced lymphocyte interaction in post capillary venules of Peyer's patches during fat absorption in rat
6. Fat assimilation
7. Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease
8. Effect of chronic incubation of Caco-2 cells with eicosapentaenoic acid (20:5, n-3) and oleic acid (18:1, n-9) on triacylglycerol production
9. Effect of dietary lipids on immunity and inflammation
10. Therapeutic efficacy of N-3 polyunsaturated fatty acid in experimental Crohn's disease
11. Interleukin-8 and neutrophil markers in colonic mucosa from patients with ulcerative colitis
12. Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation
13. Bile acids inhibit tumour necrosis factor alpha-induced interleukin-8 production in human colon epithelial cells
14. Effect of 16, 16-dimethyl prostaglandin E2 on lysosomal membrane stability in rat stomach
15. Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis
16. Cyclosporine A inhibits interleukin-8 production in human colon epithelial cell line (HT-29)
17. Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro
18. Induction of endothelin-1 synthesis by IL-2 and its modulation of rat intestinal epithelial cell growth
19. Differential cytokine expression by human intestinal epithelial cell lines: Regulated expression of interleukin-8
20. Assembly and secretion of chylomicrons by differentiated Caco-2 cells. Nascent triglycerides and preformed phospholipids are preferentially used for lipoprotein assembly
21. Cytokine-induced GRO/ CINC-1 production of intestinal epithelial cells is significantly enhanced by fatty acid absorption
22. The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells
23. Effects of intravenous omega-3 and omega-6 fat emulsion on cytokine production and delayed type hypersensitivity in burned rats receiving total parenteral nutrition
24. Docosahexaenoic acid and signaling pathways in rabbit colon
25. Stimulation of p38 phosphorylation and activity by arachidonic acid in HeLa Cells, HL60 promyelocytic leukemic cells, and human neutrophils. Evidence for cell type-specific activation of mitogen-activated protein kinases
26. Eicosapentaenoic acid enhances nitric oxide production by cultured human endothelial cells
27. Protein kinase C mediates experimental colitis in the rat
28. Regulation of interleukin-8 production in a human colon epithelial cell line (HT-29)
29. 2+-dependent protein kinase
30. 2+
31. Effects of culture with unsaturated fatty acids on lymphocyte protein kinase activities
32. Synergistic action of diacylglycerol and unsaturated fatty acid for protein kinase C activation: Its possible implications
33. Strain induces Caco-2 intestinal epithelial proliferation and differentiation via PKC and tyrosine kinase signals
34. The alpha isoform of protein kinase C is involved in signaling the response of desmosomes to wounding in cultured epithelial cells
35. 2+ signalling in rat vascular smooth muscle cells: A role for protein kinase C at physiological vasoconstrictor concentrations of vasopressin
36. Effect of medium chain triglyceride on healing process of experimental colitis induced in rat
37. Mechanism of absorption enhancement in humans after rectal administration of ampicillin in suppositories containing sodium caprate
38. Cytotoxicity of absorption enhancers in Caco-2 cell monolayers
39. Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells