Carbonic anhydrase activity modulators: Synthesis of inhibitors and activators incorporating 2-substituted-thiazol-4-yl-methyl scaffolds

Journal of Enzyme Inhibition

Volumn 16, Issue 4, 2001, Pages 351-358

  Scozzafava, Andrea ^a   Saramet, Ioana ^a   Banciu, Mircea D ^a   Supuran, Claudiu T ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Amine; Carbonic anhydrase; Histamine; Sulfamate; Sulfamide; Thiazole

Indexed keywords

2 [4 (4 BROMOPHENYLSULFONYL) PHENYL] 4 AMINOMETHYL THIAZOLE; 2 [4 (4 CHLOROPHENYLSULFONYL) PHENYL] 4 AMINOMETHYL THIAZOLE; 2 [4 (PHENYLSULFONYL) PHENYL] 4 AMINOMETHYL THIAZOLE; 2 [4 (PHENYLSULFONYL) PHENYL] THIAZOLE 4 YL METHYL SULFAMATE; 2 [4 (PHENYLSULFONYL) PHENYL] THIAZOLE 4 YL METHYL SULFAMIDE; ACETAZOLAMIDE; AMINE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; ENZYME ACTIVATOR; HISTAMINE; ISOENZYME; SODIUM; SULFANILAMIDE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; ZINC;

ARTICLE; CHEMICAL BINDING; CHEMICAL REACTION; CONTROLLED STUDY; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; PRIORITY JOURNAL;

EID: 0035690508     PISSN: 87555093     EISSN: None     Source Type: Journal    
DOI: 10.1080/14756360109162383     Document Type: Article

References (47)

1. "Activation of carbonic anhydrase isozymes"
2. "Evolution and distribution of the carbonic anhydrase gene families"