Therapeutic approaches for transplantation

Current Opinion in Immunology

Volumn 13, Issue 5, 2001, Pages 606-610

  Waldmann, H ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXYSPERGUALIN; ALEMTUZUMAB; ANTIGEN; AZATHIOPRINE; CD18 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD40 LIGAND; CD45 ANTIGEN; CD8 ANTIGEN; CYCLOSPORIN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IMMUNOSUPPRESSIVE AGENT; IMMUNOTOXIN; RAPAMYCIN; STEROID; T LYMPHOCYTE ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN SPECIFICITY; BONE MARROW; BONE MARROW TRANSPLANTATION; CELL KILLING; CHIMERA; CLINICAL TRIAL; GRAFT REJECTION; GRAFT SURVIVAL; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; NONHUMAN; ORGAN TRANSPLANTATION; REVIEW; STEM CELL TRANSPLANTATION; T LYMPHOCYTE; XENOTRANSPLANTATION;

EID: 0035479914     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(00)00268-5     Document Type: Review

References (54)

1. Actively acquired tolerance of foreign cells
2. Monoclonal antibodies to promote marrow engraftment and tissue graft tolerance
3. Mixed chimerism and transplant tolerance
4. Tolerance to vascularised organ allografts in large-animal models
5. Mixed allogeneic chimerism and renal allograft tolerance in cynomolgus monkeys
6. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment
7. Mixed chimerism and tolerance without whole body irradiation in a large animal model
8. Induction of classical transplantation tolerance in the adult
9. Administration of anti-CD40 ligand and donor bone marrow leads to hemopoietic chimerism and donor-specific tolerance without cytoreductive conditioning
10. Peripheral deletion after bone marrow transplantation with costimulatory blockade has features of both activation-induced cell death and passive cell death
11. Tolerance induction by 'megadose' transplants of CD34+ stem cells: A new option for leukemia patients without an HLA-matched donor
12. Bone marrow transplantation induces either clonal deletion or infectious tolerance depending on the dose
13. New strategies for bone marrow transplantation
14. Stable mixed hematopoietic chimerism in dog leukocyte antigen-identical littermate dogs given lymph node irradiation before and pharmacologic immunosuppression after marrow transplantation
15. Association of natural killer cell depletion with induction of mixed chimerism and allograft tolerance in non-human primates
16. CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells
17. In vivo CAMPATH-1H prevents graft-versus-host disease following nonmyeloablative stem cell transplantation
18. Clinical transplantation tolerance twelve years after prospective withdrawal of immunosuppressive drugs: Studies of chimerism and anti-donor reactivity
19. How do monoclonal antibodies induce tolerance? A role for infectious tolerance?
20. Anti-CD154 therapeutic antibodies induce infectious transplantation tolerance
21. Targeting signal 1 through CD45RB synergizes with CD40 ligand blockade and promotes long term engraftment and tolerance in stringent transplant models
22. Mechanisms of induction of tolerance to organ allografts
23. T-cell death and transplantation tolerance
24. Infectious transplantation tolerance
25. T-cell regulation and transplantation tolerance
26. IL-10 is required for regulatory T-cells to mediate tolerance to alloantigens in vivo
27. Regulating the immune response to transplants: A role for CD4+ regulatory cells?
28. Linked suppression of skin graft rejection can operate through indirect recognition
29. Differential effects of cyclosporine A, methylprednisolone, mycophenolate, and rapamycin on CD154 induction and requirement for NFκB: Implications for tolerance induction
30. Tolerance to solid organ transplants through transfer of MHC class II genes
31. The tolerant recipient: Looking great in someone else's genes
32. The role of T-cell apoptosis in transplantation tolerance
33. Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo
34. Induction of interleukin 10-producing, nonproliferating CD4(+) T-cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
35. Differentiation of T-regulatory cells by immature dendritic cells
36. Requirement of the chemokine receptor CXCR3 for acute allograft rejection
37. Chemokines and their receptors in allograft rejection
38. Chemokines, chemokine receptors, and allograft rejection
39. Prolongation of renal transplant survival in patients lacking a functional CC chemokine receptor 5 (CCR5) chemokine receptor
40. Knowledge about transplantation tolerance gained in primates
41. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand
42. Anti-CD154 monoclonal antibody and thromboembolism
43. T-cell depletion as a means of achieving tolerance
44. Peritransplant tolerance induction with anti-CD3-immunotoxin: A matter of proinflammatory cytokine control
45. Durable donor-specific T and B-cell tolerance in rhesus macaques induced with peritransplantation anti-CD3 immunotoxin and deoxyspergualin: Absence of chronic allograft nephropathy
46. Campath IH allows low-dose cyclosporine monotherapy in 31 cadaveric renal allograft recipients
47. Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine
48. Immune monitoring for rejection of kidney transplants
49. AM clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol
50. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
51. High-dose porcine hematopoietic cell transplantation combined with CD40 ligand blockade in baboons prevents an induced anti-pig humoral response
52. Long-term functional islet mass and metabolic function after xeno islet transplantation in primates
53. The immunological barrier to xenotransplantation
54. Prospects for xenotransplantation