Functional interactions between arginine-133 and aspartate-88 in the human reduced folate carrier: Evidence for a charge-pair association

Biochemical Journal

Volumn 358, Issue 2, 2001, Pages 511-516

  Liu, X Y ^a   Matherly, L H ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Methotrexate; Mutagenesis; Tetrahydrofolate

Indexed keywords

MUTAGENS; PROTEINS; SUBSTRATES;

HUMAN REDUCED FOLATE CARRIERS;

BIOCHEMISTRY;

FOLINIC ACID; GLUTAMIC ACID; HISTIDINE; LEUCINE; LYSINE; MEMBRANE PROTEIN; METHOTREXATE; MUTANT PROTEIN; REDUCED FOLATE CARRIER; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; CELL STRAIN K 562; CONTROLLED STUDY; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; ASPARTIC ACID; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CRICETINAE; HUMANS; K562 CELLS; LEUCOVORIN; MEMBRANE TRANSPORT PROTEINS; METHOTREXATE; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; RATS; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 0035448301     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3580511     Document Type: Article

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