Mutations in the reduced folate carrier gene which confer dominant resistance to 5,10-dideazatetrahydrofolate

Journal of Biological Chemistry

Volumn 273, Issue 40, 1998, Pages 25953-25960

  Tse, Archie ^a,c   Brigle, Kevin ^b,d   Taylor, Shirley M ^b   Moran, Richard G ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LOMETREXOL;

ALLELE; ANIMAL CELL; ARTICLE; BINDING SITE; DOMINANT INHERITANCE; ENZYME SUBSTRATE; FOLATE METABOLISM; GENE MUTATION; GENETIC TRANSFECTION; HETEROZYGOTE; LEUKEMIA CELL; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING;

ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL DIVISION; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE; FOLIC ACID; KINETICS; LEUCOVORIN; LEUKEMIA L1210; METHOTREXATE; MICE; PHENOTYPE; POINT MUTATION; PTEROYLPOLYGLUTAMIC ACIDS; RECEPTORS, CELL SURFACE; RNA, MESSENGER; TETRAHYDROFOLATES; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0032475923     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.40.25953     Document Type: Article

References (24)

1. Tse, A., and Moran, R. G. (1998) J. Biol. Chem. 273, 25944-25952
2. Taylor, E. C., Harrington, P. J., Fletcher, S. R., Beardsley, G. P., and Moran, R. G. (1985) J. Med. Chem. 28, 914-921
3. Moran, R. G., Baldwin, S. W., Taylor, E. C., and Shih, C. (1989) J. Biol. Chem. 264, 21047-21051
4. Beardsley, G. P., Moroson, B. A., Taylor, E. C., and Moran, R. G. (1989) J. Biol. Chem. 264, 328-333
5. Schuetz, J. D., Westin, E. H., Matherly, L. H., Pincus, R., Swetlow, p. S., and Goldman, I. D. (1989) J. Biol. Chem. 264, 16261-16267
6. Brigle, K. E., Spinella, M. J., Westin, E. H., and Goldman, I. D. (1994) Biochem. Pharmacol. 47, 337-345
7. Keyomarsi, K., and Moran, R. G. (1986) Cancer Res. 46, 5229-5235
8. Moran, R. G., Werkheiser, W. C., and Zakrzewski, S. F. (1976) J. Biol. Chem. 251, 3569-3575
9. Sirotnak, F. M., Goutas, L. J., Jacobsen, D. M., Mines, L. S., Barrueco, J. R., Gaumont, Y., and Kisliuk, R. L. (1987) Biochem. Pharmacol. 36, 1659-1667
10. Assaraf, Y., and Goldman, I. D. (1997) J. Biol. Chem. 272, 17460-17466
11. Puissan, C., and Houdebine, L. M. (1990) BioTechniques 8, 148-149
12. Dixon, K. H., Lanpher, B. C., Chiu, J., Kelley, K., and Cowan, K. H. (1994) J. Biol. Chem. 269, 17-20
13. Brigle, K. E., Spinella, M. J., Sierra, E. E., and Goldman, I. D. (1995) J. Biol. Chem. 270, 22974-22979
14. Tolner, B., Roy, K., and Sirotnak, F. M. (1997) Gene (Amst.) 189, 1-7
15. Goldman, I. D., Lichtenstein, N. S., and Oliverio, V. T. (1968) J. Biol. Chem. 243, 5007-5017
16. Henderson, G. B., and Zevely, E. M. (1984) J. Biol. Chem. 259, 1526-1531
17. Sirotnak, F. M. (1985) Cancer Res. 45, 3992-4000
18. Henderson, G. B., and Strauss, B. P. (1990) Cancer Res. 50, 1709-1714
19. Kamen, B. A., Wang, M. T., Streckfuss, A. J., Peryea, X., and Anderson, R. G. W. (1988) J. Biol. Chem. 263, 13602-13609
20. Matherly, L. H., Angeles, S. M., and McGuire, J. J. (1993) Biochem. Pharmacol. 46, 2185-2195
21. Alati, T., Worzalla, J. F., Shih, C., Bewley, J. R., Lewis, S., Moran, R. G., and Grindey, G. B. (1996) Cancer Res. 56, 331-335
22. Young, C. W., Currie, V. E., Muindi, J. F., Saltz, L. B., Pisters, K. M. W., Esposito, A. J., and Dyke, R. W. (1992) Proc. Am. Assoc. Cancer Res. 33, 406
23. Zhao, R., Assaraf, Y. G., and Goldman, I. D. (1998) J. Biol. Chem. 273, 7873-7879
24. Laohavinij, S., Wedge, S. R., Lind, M. J., Bailey, N., Humphreys, A., Proctor, M., Chapman, F., Simmons, D., Oakley, A., Robson, L., Gumbrell, L., Taylor, G. A., Thomas, H. D., Boddy, A. V., Newell, D. R., and Calvert, A. H. (1996) Invest. New Drugs 14, 325-335