Dipolar couplings as a probe of molecular dynamics and structure in solution

Current Opinion in Structural Biology

Volumn 11, Issue 5, 2001, Pages 532-539

  Tolman, Joel R ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; REVIEW; STRUCTURE ANALYSIS; TECHNIQUE;

EID: 0035443893     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-440X(00)00245-1     Document Type: Review

References (69)

1. NMR structures of biomolecules using field oriented media and residual dipolar couplings
2. Protein structure and dynamics from field induced residual dipolar couplings
3. Improved low pH bicelle system for orienting macromolecules over a wide temperature range
4. Bicelle-based liquid crystals for NMR measurement of dipolar couplings at acidic and basic pH values
5. Improved dilute bicelle solutions for high-resolution NMR of biological macromolecules
6. Cellulose crystallites: A new and robust liquid crystalline medium for the measurement of residual dipolar couplings
7. Purple membrane induced alignment of biological macromolecules in the magnetic field
8. NMR measurement of dipolar couplings in proteins aligned by transient binding to purple membrane fragments
9. Use of a novel aqueous liquid crystalline medium for high-resolution NMR of macromolecules in solution
10. Characterization of surfactant liquid crystal phases suitable for molecular alignment and measurement of dipolar couplings
11. Alignment of biological macromolecules in novel nonionic liquid crystalline media for NMR experiments
12. Prediction of sterically induced alignment in a dilute liquid crystalline phase; aid to protein structure determination by NMR
13. Modulation of the alignment tensor of macromolecules dissolved in a dilute liquid crystalline medium
14. Variation of molecular alignment as a means of resolving orientational ambiguities in protein structures from dipolar couplings
15. Alignment of biopolymers in strained gels: A new way to create detectable dipole-dipole couplings in high resolution biomolecular NMR
16. Solution NMR of proteins within polyacrylamide gels: Diffusional properties and residual alignment by mechanical stress or embedding of oriented purple membranes
17. Impact of residual dipolar couplings on the accuracy of NMR structures determined from a minimal number of NOE restraints
18. Determining DNA global structure and DNA bending by application of NMR residual dipolar couplings
19. The NMR structure of a DNA dodecamer in an aqueous dilute liquid crystalline phase
20. Solution structure of an A-tract DNA bend
21. Assessment of zinc finger orientations by residual dipolar coupling constants
22. A refined solution structure of hen lysozyme determined using residual dipolar coupling data
23. Solution structure of DinI provides insight into its mode of RecA inactivation
24. Global folds of proteins with low densities of NOEs using residual dipolar couplings: Application to the 370-residue maltodextrin-binding protein
25. Nuclear magnetic resonance in the era of structural genomics
26. Rapid determination of protein folds using residual dipolar couplings
27. De novo determination of protein structure by NMR using orientational and long-range order restraints
28. Determination of protein backbone structure using only residual dipolar couplings
29. New techniques in structural NMR - Anisotropic interactions
30. Accurate and rapid docking of protein-protein complexes on the basis of intermolecular nuclear Overhauser enhancement data and dipolar couplings by rigid body minimization
31. Domain orientation and dynamics in multidomain proteins from residual dipolar couplings
32. Orienting domains in proteins using dipolar couplings measured by liquid-state NMR: Differences in solution and crystal forms of maltodextrin binding protein loaded with beta-cyclodextrin
33. Ligand-induced structural changes to maltodextrin-binding protein as studied by solution NMR spectroscopy
34. What is the average conformation of bacteriophage T4 lysozyme in solution? A domain orientation study using dipolar couplings measured by solution NMR
35. Determination of the relative orientation of the two halves of the domain-swapped dimer of cyanovirin-N in solution using residual dipolar couplings and rigid body minimization
36. Field- and phage-induced dipolar couplings in a homodimeric DNA quadruplex, relative orientation of G•(C-A) triad and G-tetrad motifs and direct determination of C2 symmetry axis orientation
37. Global structure of RNA determined with residual dipolar couplings
38. Solution structure of the phosphoryl transfer complex between the signal transducing proteins HPr and IIA(Glucose) of the Escherichia coli phosphoenolpyruvate: Sugar phosphotransferase system
39. Alignment of the HTLV-I rex peptide bound to its target RNA aptamer from magnetic field induced residual dipolar couplings and intermolecular hydrogen bonds
40. Nuclear magnetic resonance characterization of the myristoylated, N-terminal fragment of ADP-ribosylation factor 1 in a magnetically oriented membrane array
41. Measurement of dipolar couplings in a transducin peptide fragment weakly bound to oriented photo-activated rhodopsin
42. Residual dipolar coupling derived orientational constraints on ligand geometry in a 53 kDa protein-ligand complex
43. Localization of the binding site for the oligosaccharide moiety of Gb3 on verotoxin 1 using NMR residual dipolar coupling measurements
44. Molecular symmetry as an aid to geometry determination in ligand protein complexes
45. NMR spectroscopy of large molecules and multimolecular assemblies in solution
46. New developments in isotope labeling strategies for protein NMR spectroscopy
47. Rapid validation of the overall structure of an internal domain-swapped mutant of the anti-HIV protein cyanovirin-N using residual dipolar couplings
48. Discovering high-affinity ligands for proteins: SAR by NMR
49. Application of residual dipolar coupling measurements to identify conformational changes in RNA induced by antibiotics
50. Wild-type and Met-65→Leu variants of human cystatin A are functionally and structurally identical
51. Structural basis for thermostability in aporubredoxins from Pyrococcus furiosus and Clostridium pasteurianum
52. Conformations of the regulatory domain of cardiac troponin C examined by residual dipolar couplings
53. NMR assignments, secondary structure, and global fold of calerythrin, an EF-hand calcium-binding protein from Saccharopolyspora erythraea
54. Recognition of protein folds via dipolar couplings
55. DipoCoup: A versatile program for 3D-structure homology comparison based on residual dipolar couplings and pseudocontact shifts
56. Protein structural motif recognition via NMR residual dipolar couplings
57. Study of conformational rearrangement and refinement of structural homology models by the use of heteronuclear dipolar couplings
58. Protein structure determination using molecular fragment replacement and NMR dipolar couplings
59. How tetrahedral are methyl groups in proteins? A liquid crystal NMR study
60. Determination of relative N-H-N N-C′, C-α-C′, andC(α)-H-α effective bond lengths in a protein by NMR in a dilute liquid crystalline phase
61. H-N hydrogen bond lengths in double stranded DNA from internucleotide dipolar couplings
62. Determining stoichiometry in homomultimeric nucleic acid complexes using magnetic field induced residual dipolar couplings
63. A method for direct determination of helical parameters in nucleic acids using residual dipolar couplings
64. Protein side-chain rotamers from dipolar couplings in a liquid crystalline phase
65. Chi-1 torsion angle dynamics in proteins from dipolar couplings
66. Structural and dynamic analysis of residual dipolar coupling data for proteins
67. Model free approach to the dynamic interpretation of residual dipolar couplings in globular proteins
68. NMR evidence for slow collective motions in cyanometmyoglobin
69. Are proteins even floppier than we thought?