Peroxynitrite-mediated DNA strand breakage activates poly(ADP-ribose) synthetase and causes cellular energy depletion in a nonseptic shock model induced by Zymosan in the rat

Shock

Volumn 9, Issue 5, 1998, Pages 336-340

  Cuzzocrea, Salvatore ^a   Zingarelli, Basilia ^a,b   Caputi, Achille P ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINOBENZAMIDE; 3-AMINOBENZAMIDE; BENZAMIDE DERIVATIVE; N(G) NITROARGININE METHYL ESTER; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRATE; NITRIC OXIDE SYNTHASE; OXIDIZING AGENT; PEROXYNITRIC ACID; ZYMOSAN;

ANIMAL; ARTICLE; DISEASE MODEL; DNA DAMAGE; DRUG EFFECT; ENERGY METABOLISM; ENZYME ACTIVATION; MALE; METABOLISM; MITOCHONDRION; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PERITONEUM MACROPHAGE; PHYSIOLOGY; RAT; SHOCK; SPRAGUE DAWLEY RAT;

ANIMALS; BENZAMIDES; DISEASE MODELS, ANIMAL; DNA DAMAGE; ENERGY METABOLISM; ENZYME ACTIVATION; MACROPHAGES, PERITONEAL; MALE; MITOCHONDRIA; NAD; NG-NITROARGININE METHYL ESTER; NIACINAMIDE; NITRATES; NITRIC OXIDE SYNTHASE; OXIDANTS; OXYGEN CONSUMPTION; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, SPRAGUE-DAWLEY; SHOCK; ZYMOSAN;

EID: 0032061048     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199805000-00004     Document Type: Article

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