Clinical and neurochemical effect of acute tryptophan depletion in unaffected relatives of patients with bipolar affective disorder

Biological Psychiatry

Volumn 50, Issue 3, 2001, Pages 184-190

  Quintin, Philippe ^b,e   Benkelfat, Chawki ^a   Launay, Jean Marie ^d,e   Arnulf, Isabelle ^e   Pointereau Bellenger, Agnes ^b,e   Barbault, Sandrine ^a   Alvarez, Jean Claude ^d,e   Varoquaux, Odile ^e,g   Perez Diaz, Fernando ^e,f   Jouvent, Roland ^e,f   Leboyer, Marion ^a,c,e  

^a MCGILL UNIVERSITY   (Canada)

^b Hôpital Albert Chenevier et Henri Mondor   (France)

^c HENRI MONDOR HOSPITAL   (France)

^d HÔPITAL LARIBOISIÈRE   (France)

^e Centre d'Investigation Clinique (IA)   (France)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^g CENTRE HOSPITALIER DE VERSAILLES   (France)

Author keywords

Bipolar affective disorder; Endophenotype; Serotonin transporter; Tryptophan depletion; Unaffected relatives

Indexed keywords

AMINO ACID; IMIPRAMINE; PLACEBO; SEROTONIN; SEROTONIN TRANSPORTER; TRYPTOPHAN;

ADULT; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOCHEMISTRY; BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPLETION; DISEASE PREDISPOSITION; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; HUMAN EXPERIMENT; IMPULSIVENESS; INGESTION; MALE; MANIC DEPRESSIVE PSYCHOSIS; MEASUREMENT; MOOD; NEUROCHEMISTRY; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RELATIVE; SEROTONIN BLOOD LEVEL; THROMBOCYTE;

ACUTE DISEASE; ADULT; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BIPOLAR DISORDER; BLOOD PLATELETS; BRAIN; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; IMIPRAMINE; MALE; SEROTONIN; SYNAPTIC TRANSMISSION; TRYPTOPHAN;

EID: 0035423184     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(01)01140-4     Document Type: Article

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