DNA molecular electrostatic potential: Novel perspectives for the mechanism of action of anticancer drugs involving electron transfer and oxidative stress

Anti-Cancer Drug Design

Volumn 16, Issue 4-5, 2001, Pages 175-184

  Kovacic, Peter ^a   Wakelin, Laurence P G ^b  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Alkylating agents; Anticancer drugs; Antimicrobial agents; Base ionization potentials; DNA; DNA binding toxins; Electron transfer; Hopping mechanism; Intercalating agents; Metal ions; Molecular electrostatic potential; Oxidative stress; Quinones

Indexed keywords

ALKYLATING AGENT; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; DNA; DOUBLE STRANDED DNA; GUANINE; INTERCALATING AGENT; METAL ION; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; FREE RADICAL; LIGAND;

CATALYSIS; DNA BINDING; DNA STRUCTURE; DRUG DESIGN; DRUG MECHANISM; ELECTRIC POTENTIAL; ELECTRICITY; ELECTRON TRANSPORT; ENERGY TRANSFER; LIGAND BINDING; MOLECULAR ELECTROSTATIC POTENTIAL; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; QUANTUM MECHANICS; REVIEW; ANIMAL; CHEMISTRY; DRUG EFFECT; ELECTROCHEMISTRY; HUMAN; QUANTUM THEORY;

ANIMALS; ANTINEOPLASTIC AGENTS; DNA; ELECTROCHEMISTRY; ELECTRON TRANSPORT; FREE RADICALS; GUANINE; HUMANS; INTERCALATING AGENTS; LIGANDS; OXIDATIVE STRESS; QUANTUM THEORY;

EID: 0035413691     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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