A Chlamydia trachomatis UDP-N-acetylglucosamine acyltransferase selective for myristoyl-acyl carrier protein: Expression in Escherichia coli and formation of hybrid lipid A species

Journal of Biological Chemistry

Volumn 276, Issue 22, 2001, Pages 19565-19574

  Sweet, Charles R ^a   Lin, Shanhua ^b   Cotter, Robert J ^b   Raetz, Christian R H ^a,b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CLONING; ESCHERICHIA COLI; ESTERS; GENES; IONIZATION; LIPIDS;

ANTI-INFLAMMATORY AGENTS;

ENZYMES;

CARRIER PROTEIN; ERYTHROMYCIN; LIPID A; MYRISTOYL ACYL CARRIER PROTEIN; RIFAMPICIN; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE; URIDINE N ACETYLGLUCOSAMINE ACYLTRANSFERASE; ACYL (ACYL CARRIER PROTEIN) UDP N ACETYLGLUCOSAMINE ACYLTRANSFERASE; ACYL CARRIER PROTEIN; ACYL-(ACYL-CARRIER-PROTEIN)-UDP-N-ACETYLGLUCOSAMINE ACYLTRANSFERASE; ACYLTRANSFERASE; HYBRID PROTEIN; RECOMBINANT PROTEIN;

ANTIBIOTIC RESISTANCE; ARTICLE; CHLAMYDIA TRACHOMATIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE EXPRESSION; IN VIVO STUDY; LIPID ANALYSIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; BIOSYNTHESIS; CELL DIVISION; CHEMICAL MODEL; CHEMISTRY; ENZYMOLOGY; ION EXCHANGE CHROMATOGRAPHY; LIPID METABOLISM; MASS SPECTROMETRY; METABOLISM; PLASMID; TEMPERATURE; TIME;

CHLAMYDIA TRACHOMATIS; ESCHERICHIA COLI; NEGIBACTERIA; RICKETTSIALES;

ACYL CARRIER PROTEIN; ACYLTRANSFERASES; CELL DIVISION; CHLAMYDIA TRACHOMATIS; CHROMATOGRAPHY, ION EXCHANGE; CLONING, MOLECULAR; ESCHERICHIA COLI; LIPID A; LIPID METABOLISM; MODELS, CHEMICAL; PLASMIDS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SUBSTRATE SPECIFICITY; TEMPERATURE; TIME FACTORS;

EID: 0035378670     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101868200     Document Type: Article

References (54)

1. Raetz, C. R. H. (1990) Annu. Rev. Biochem. 59, 129-170
2. Rietschel, E. T., Kirikae, T., Schade, F. U., Mamat, U., Schmidt, G., Loppnow, H., Ulmer, A. J., Zähringer, U., Seydel, U., Di Padova, F., Schreier, M., and Brade, H. (1994) FASEB J. 8, 217-225
3. Brade, H., Opal, S. M., Vogel, S. N., and Morrison, D. C. (eds) (1999) Endotoxin in Health and Disease, Marcel Dekker, Inc., New York
4. Hoshino, K., Takeuchi, O., Kawai, T., Sanjo, H., Ogawa, T., Takeda, Y., Takeda, K., and Akira, S. (1999) J. Immunol. 162, 3749-3752
5. Poltorak, A., He, X., Smirnova, I., Liu, M. Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., Freudenberg, M., Ricciardi-Castagnoli, P., Layton, B., and Beutler, B. (1998) Science 282, 2085-2088
6. Aderem, A., and Ulevitch, R. J. (2000) Nature 406, 782-787
7. Lien, E., Means, T. K., Heine, H., Yoshimura, A., Kusumoto, S., Fukase, K., Fenton. M. J., Oikawa, M., Qureshi, N., Monks, B., Finberg, R. W., Ingalls, R. R., and Golenbock, D. T. (2000) J. Clin. Invest. 105, 497-504
8. Wyckoff, T. J. O., Raetz, C. R. H., and Jackman, J. E. (1998) Trends Microbiol. 6, 154-159
9. Anderson, M. S., and Raetz, C. R. H. (1987) J. Biol. Chem. 262, 5159-5169
10. Coleman, J., and Raetz, C. R. H. (1988) J. Bacteriol. 170, 1268-1274
11. Anderson, M. S., Bull, H. S., Galloway, S. M., Kelly, T. M., Mohan, S., Radika, K., and Raetz, C. R. H. (1993) J. Biol. Chem. 268, 19858-19865
12. Williamson, J. M., Anderson, M. S., and Raetz, C. R. H. (1991) J. Bacteriol. 173, 3591-3596
13. Dotson, G. D., Kaltashov, I. A., Cotter, R. J., and Raetz, C. R. (1998) J. Bacteriol. 180, 330-337
14. Odegaard, T. J., Kaltashov, I. A., Cotter, R. J., Steeghs, L., van der Ley, P., Khan, S., Maskell, D. J., and Raetz, C. R. H. (1997) J. Biol. Chem. 272, 19688-19696
15. Raetz, C. R. H., and Roderick, S. L. (1995) Science 270, 997-1000
16. Wyckoff, T. J., and Raetz, C. R. H. (1999) J. Biol. Chem. 274, 27047-27055
17. Rietschel, E. T., Brade, L., Lindner, B., and Zähringer, U. (1992) in Bacterial Endotoxic Lipopolysaccharides, Vol. I: Molecular Biochemistry and Cellular Biology (Morrison, D. C., and Ryan, J. L., eds) Vol. I, pp. 3-41, CRC Press, Boca Raton, FL
18. Qureshi, N., Kaltashov, I., Walker, K., Doroshenko, V., Cotter, R. J., Takayama, K., Sievert, T. R., Rice, P. A., Lin, J. S., and Golenbock, D. T. (1997) J. Biol. Chem. 272, 10594-10600
19. Rund, S., Lindner, B., Brade, H., and Holst, O. (1999) J. Biol. Chem. 274, 16819-16824
20. Schachter, J., and Caldwell, H. D. (1980) Annu. Rev. Microbiol. 34, 285-309
21. Brade, H. (1999) in Endotoxin in Health and Disease (Brade, H., Opal, S. M., Vogel, S. N., and Morrison, D. C., eds) pp. 229-242, Marcel Dekker, Inc., New York
22. Karimi, S. T., Schloemer, R. H., and Wilde, C. E. (1989) Infect. Immun. 57, 1780-1785
23. Hackstadt, T., Rockey, D. D., Heinzen, R. A., and Scidmore, M. A. (1996) EMBO J. 15, 964-977
24. Wylie, J. L., Hatch, G. M., and McClarty, G. (1997) J. Bacteriol. 179, 7233-7242
25. Hatch, G. M., and McClarty, G. (1998) Infect. Immun. 66, 3727-3735
26. Stephens, R. S., Kalman, S., Lammel, C., Fan, J., Marathe, R., Aravind, L., Mitchell, W., Olinger, L., Tatusov, R. L., Zhao, Q., Koonin, E. V., and Davis, R. W. (1998) Science 282, 754-759
27. Karow, M., and Georgopoulos, C. (1992) J. Bacteriol. 174, 702-710
28. Clementz, T., Zhou, Z., and Raetz, C. R. H. (1997) J. Biol. Chem. 272, 10353-10360
29. Galloway, S. M., and Raetz, C. R. H. (1990) J. Biol. Chem. 265, 6394-6402
30. Onishi, H. R., Pelak, B. A., Gerckens, L. S., Silver, L. L., Kahan, F. M., Chen, M. H., Patchett, A. A., Galloway, S. M., Hyland, S. A., Anderson, M. S., and Raetz, C. R. H. (1996) Science 274, 980-982
31. Jackman, J. E., Fierke, C. A., Tumey, L. N., Pirrung, M., Uchiyama, T., Tahir, S. H., Hindsgaul, O., and Raetz, C. R. H. (2000) J. Biol. Chem. 275, 11002-11009
32. Wyckoff, T. J. O., Lin, S., Cotter, R. J., Dotson, G. D., and Raetz, C. R. H. (1998) J. Biol. Chem. 273, 32369-32372
33. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor, Cold Spring Harbor, NY
34. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (eds) (1989) Current Protocols in Molecular Biology, John Wiley & Sons, New York
35. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J. (1997) Nucleic Acids Res. 25, 3389-3402
36. Blattner, F. R., Plunkett, G., Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., and Shao, Y. (1997) Science 277, 1453-1474
37. Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985) Anal. Biochem. 150, 76-85
38. Vuorio, R., and Vaara, M. (1992) Antimicrob. Agents Chemother. 37, 354-356
39. Vaara, M. (1993) Antimicrob. Agents Chemother. 37, 2255-2260
40. Zhou, Z., Lin, S., Cotter, R. J., and Raetz, C. R. H. (1999) J. Biol. Chem. 274, 18503-18514
41. Mohan, S., Kelly, T. M., Eveland, S. S., Raetz, C. R. H., and Anderson, M. S. (1994) J. Biol. Chem. 269, 32896-32903
42. Somerville, J. E., Jr., Cassiano, L., Bainbridge, B., Cunningham, M. D., and Darveau, R. P. (1996) J. Clin. Invest. 97, 359-365
43. Zhou, Z., White, K. A., Polissi, A., Georgopoulos, C., and Raetz, C. R. H. (1998) J. Biol. Chem. 273, 12466-12467.5
44. Khan, S. A., Everest, P., Servos, S., Foxwell, N., Zahringer, U., Brade, H., Rietschel, E. T., Dougan, G., Charles, I. G., and Maskell, D. J. (1998) Mol. Microbiol. 29, 571-579
45. Low, K. B., Ittensohn, M., Le, T., Platt, J., Sodi, S., Amoss, M., Ash, O., Carmichael, E., Chakraborty, A., Fischer, J., Lin, S. L., Luo, X., Miller, S. I., Zheng, L., King, I., Pawelek, J. M., and Bermudes, D. (1999) Nat. Biotechnol. 17, 37-41
46. Ingalls, R. R., Rice, P. A., Qureshi, N., Takayama, K., Lin, J. S., and Golenbock, D. T. (1995) Infect. Immun. 63, 3125-3130
47. Ray, B. L., Painter, G., and Raetz, C. R. H. (1984) J. Biol. Chem. 259, 4852-4859
48. Crowell, D. N., Reznikoff, W. S., and Raetz, C. R. H. (1987) J. Bacteriol. 169, 5727-5734
49. Radika, K., and Raetz, C. R. H. (1988) J. Biol. Chem. 263, 14859-14867
50. Babinski, K. J., and Raetz, C. R. H. (1998) FASEB. J. 12, A1288
51. Raetz, C. R. H. (1996) in Escherichia coli and Salmonella: Cellular and Molecular Biology (Neidhardt, F. C., ed) Vol. 1, Second Ed., pp. 1035-1063, American Society for Microbiology, Washington, D. C
52. Raetz, C. R. H., and Kennedy, E. P. (1973) J. Biol. Chem. 248, 1098-1105
53. Costello, C. E., and Vath, J. E. (1990) Methods Enzymol. 193, 738-768
54. Bishop, R. E., Gibbons, H. S., Guina, T., Trent, M. S., Miller, S. I., and Raetz, C. R. H. (2000) EMBO J. 19, 5071-5080