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Volumn 24, Issue 6, 2001, Pages 305-307

Vaccine development for Alzheimer's disease: A shot of good news

Author keywords

[No Author keywords available]

Indexed keywords

ABETA PEPTIDE VACCINE; UNCLASSIFIED DRUG; VACCINE;

EID: 0035370637     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-2236(00)01796-3     Document Type: Review
Times cited : (19)

References (18)
  • 1
    • 0033536163 scopus 로고    scopus 로고
    • Immunization with Aβ attenuates Alzheimer's disease-like pathology in the PDAPP mouse
    • Schenk D., et al. Immunization with Aβ attenuates Alzheimer's disease-like pathology in the PDAPP mouse. Nature. 400:1999;173-177.
    • (1999) Nature , vol.400 , pp. 173-177
    • Schenk, D.1
  • 2
    • 0034697948 scopus 로고    scopus 로고
    • Further progress on a β-amyloid vaccine
    • Helmuth L. Further progress on a β-amyloid vaccine. Science. 289:2000;375.
    • (2000) Science , vol.289 , pp. 375
    • Helmuth, L.1
  • 3
    • 84984755327 scopus 로고    scopus 로고
    • Vaccination with Aβ peptide prevents memory deficits in an animal model of Alzheimer's disease
    • Morgan D., et al. Vaccination with Aβ peptide prevents memory deficits in an animal model of Alzheimer's disease. Nature. 408:2000;982-985.
    • (2000) Nature , vol.408 , pp. 982-985
    • Morgan, D.1
  • 4
    • 0031914718 scopus 로고    scopus 로고
    • Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
    • Holcomb L., et al. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat. Med. 4:1998;97-100.
    • (1998) Nat. Med. , vol.4 , pp. 97-100
    • Holcomb, L.1
  • 5
    • 0034736182 scopus 로고    scopus 로고
    • Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain
    • Wengenack T.M., et al. Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain. Neuroscience. 101:2000;939-944.
    • (2000) Neuroscience , vol.101 , pp. 939-944
    • Wengenack, T.M.1
  • 6
    • 1842288033 scopus 로고    scopus 로고
    • Measuring memory in a mouse model of Alzheimer's disease
    • Routtenberg A. Measuring memory in a mouse model of Alzheimer's disease. Science. 277:1997;839-841.
    • (1997) Science , vol.277 , pp. 839-841
    • Routtenberg, A.1
  • 7
    • 0032855097 scopus 로고    scopus 로고
    • Progress toward valid transgenic mouse models for Alzheimer's disease
    • Guenette S.Y., Tanzi R.E. Progress toward valid transgenic mouse models for Alzheimer's disease. Neurobiol. Aging. 20:1999;201-211.
    • (1999) Neurobiol. Aging , vol.20 , pp. 201-211
    • Guenette, S.Y.1    Tanzi, R.E.2
  • 8
    • 0035830686 scopus 로고    scopus 로고
    • Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes
    • Arendash G.W., et al. Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes. Brain Res. 891:2001;42-53.
    • (2001) Brain Res. , vol.891 , pp. 42-53
    • Arendash, G.W.1
  • 9
    • 0004956085 scopus 로고    scopus 로고
    • Correlation between cognitive deficits and Aβ deposits in transgenic APP+PS1 mice.
    • (in press)
    • Gordon, M.N. et al. Correlation between cognitive deficits and Aβ deposits in transgenic APP+PS1 mice. Neurobiol. Aging (in press).
    • Neurobiol. Aging
    • Gordon1    M.N. et, al.2
  • 10
    • 0032756213 scopus 로고    scopus 로고
    • Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: Lack of association with amyloid deposits
    • Holcomb L.A., et al. Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits. Behav. Genet. 29:1999;177-185.
    • (1999) Behav. Genet. , vol.29 , pp. 177-185
    • Holcomb, L.A.1
  • 11
    • 0034700480 scopus 로고    scopus 로고
    • A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease
    • Chen G., et al. A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease. Nature. 408:2000;975-979.
    • (2000) Nature , vol.408 , pp. 975-979
    • Chen, G.1
  • 12
    • 0034700471 scopus 로고    scopus 로고
    • Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
    • Janus C., et al. Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature. 408:2000;979-982.
    • (2000) Nature , vol.408 , pp. 979-982
    • Janus, C.1
  • 13
    • 0022273981 scopus 로고
    • Analysis of age-related impairments in learning and memory in rodent models
    • Ingram D.K. Analysis of age-related impairments in learning and memory in rodent models. Ann. New York Acad. Sci. 444:1985;313-331.
    • (1985) Ann. New York Acad. Sci. , vol.444 , pp. 313-331
    • Ingram, D.K.1
  • 14
    • 0033230210 scopus 로고    scopus 로고
    • Is age-related maculopathy associated with Alzheimer's disease? The Rotterdam Study
    • Klaver C.C., et al. Is age-related maculopathy associated with Alzheimer's disease? The Rotterdam Study. Am. J. Epidemiol. 150:1999;963-968.
    • (1999) Am. J. Epidemiol. , vol.150 , pp. 963-968
    • Klaver, C.C.1
  • 15
    • 0029892805 scopus 로고    scopus 로고
    • Retinal pathology in Alzheimer's disease. I. Ganglion cell loss in foveal/parafoveal retina
    • Blanks J.C., et al. Retinal pathology in Alzheimer's disease. I. Ganglion cell loss in foveal/parafoveal retina. Neurobiol. Aging. 17:1996;377-384.
    • (1996) Neurobiol. Aging , vol.17 , pp. 377-384
    • Blanks, J.C.1
  • 16
    • 0034213718 scopus 로고    scopus 로고
    • High-level neuronal expression of Aβ1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
    • Mucke L., et al. High-level neuronal expression of Aβ1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J. Neurosci. 20:2000;4050-4058.
    • (2000) J. Neurosci. , vol.20 , pp. 4050-4058
    • Mucke, L.1
  • 17
    • 0001216824 scopus 로고    scopus 로고
    • Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes
    • Wong T.P., et al. Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes. J. Neurosci. 19:1999;2706-2716.
    • (1999) J. Neurosci. , vol.19 , pp. 2706-2716
    • Wong, T.P.1
  • 18
    • 0033872024 scopus 로고    scopus 로고
    • Age-related Aβ deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and Aβ precursor protein Swedish mutant is not associated with global neuronal loss
    • Takeuchi A., et al. Age-related Aβ deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and Aβ precursor protein Swedish mutant is not associated with global neuronal loss. Am. J. Pathol. 157:2000;331-339.
    • (2000) Am. J. Pathol. , vol.157 , pp. 331-339
    • Takeuchi, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.