Cerium(IV)/lanthanide(III)/dextran ternary solutions for efficient and homogeneous dna hydrolysis

Nucleosides and Nucleotides

Volumn 17, Issue 1-3, 1998, Pages 613-623

  Sumaoka, Jun ^a   Kajimura, Ayako ^a   Imai, Takamitsu ^a   Ohno, Masayuki ^a   Komiyama, Makoto ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CERIUM; DEXTRAN; LANTHANIDE;

ARTICLE; CATALYST; DNA SYNTHESIS; ENZYME SYNTHESIS; HALF LIFE TIME; HYDROLYSIS; REACTION ANALYSIS; ULTRAFILTRATION;

EID: 0031912879     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319808005204     Document Type: Article

References (31)

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2. Reviews: (a) Dervan, P.B. Science (Washington D.C.), 1986, 232, 464-471. (b) Komiyama, M. J. Biochem. 1995, 118, 665-670.
3. Reviews: (a) Dervan, P.B. Science (Washington D.C.), 1986, 232, 464-471. (b) Komiyama, M. J. Biochem. 1995, 118, 665-670.
4. Chin, J.; Banaszczyk, V.; Jubian, V.; Zou, X. J. Am. Chem. Soc., 1989, 111, 186-190.
5. Non-enzymatic scission of supercoiled plasmid DNA was reported: (a) Basile, L.A.; Raphael, A.L.; Barton, J.K. J. Am. Chem. Soc. 1987, 109, 7550-7551. (b) Schnaith, L.M.T.; Hanson, R.S.; Que, L., Jr. Proc. Natl. Acad. Sci. USA. 1994, 91, 569-573. (c) Dixon, N.E.; Geue, R.J.; Lambert, J.N.; Moghaddas, S.; Pearce, D.A.; Sargeson, A.M. J. Chem. Soc., Chem. Commun. 1996, 1287-1288. (d) Hegg, E.L.; Burstyn, J.N. Inorg. Chem. 1996, 35, 7474-7481. (e) Ihara, T.; Shimura, H.; Ohmori, K.; Tsuji, H.; Takeuchi, J.; Takagi, M. Chem. Lett. 1996, 687-688. (f) Rammo, J.; Hettich, R.; Roigk, A.; Schneider, H.-J. J. Chem. Soc., Chem. Commun. 1996, 105-107. (g) Hashimoto, S.; Nakamura, Y. J. Chem. Soc., Perkin Trans, 1 1996, 2623-2628.
6. Non-enzymatic scission of supercoiled plasmid DNA was reported: (a) Basile, L.A.; Raphael, A.L.; Barton, J.K. J. Am. Chem. Soc. 1987, 109, 7550-7551. (b) Schnaith, L.M.T.; Hanson, R.S.; Que, L., Jr. Proc. Natl. Acad. Sci. USA. 1994, 91, 569-573. (c) Dixon, N.E.; Geue, R.J.; Lambert, J.N.; Moghaddas, S.; Pearce, D.A.; Sargeson, A.M. J. Chem. Soc., Chem. Commun. 1996, 1287-1288. (d) Hegg, E.L.; Burstyn, J.N. Inorg. Chem. 1996, 35, 7474-7481. (e) Ihara, T.; Shimura, H.; Ohmori, K.; Tsuji, H.; Takeuchi, J.; Takagi, M. Chem. Lett. 1996, 687-688. (f) Rammo, J.; Hettich, R.; Roigk, A.; Schneider, H.-J. J. Chem. Soc., Chem. Commun. 1996, 105-107. (g) Hashimoto, S.; Nakamura, Y. J. Chem. Soc., Perkin Trans, 1 1996, 2623-2628.
7. Non-enzymatic scission of supercoiled plasmid DNA was reported: (a) Basile, L.A.; Raphael, A.L.; Barton, J.K. J. Am. Chem. Soc. 1987, 109, 7550-7551. (b) Schnaith, L.M.T.; Hanson, R.S.; Que, L., Jr. Proc. Natl. Acad. Sci. USA. 1994, 91, 569-573. (c) Dixon, N.E.; Geue, R.J.; Lambert, J.N.; Moghaddas, S.; Pearce, D.A.; Sargeson, A.M. J. Chem. Soc., Chem. Commun. 1996, 1287-1288. (d) Hegg, E.L.; Burstyn, J.N. Inorg. Chem. 1996, 35, 7474-7481. (e) Ihara, T.; Shimura, H.; Ohmori, K.; Tsuji, H.; Takeuchi, J.; Takagi, M. Chem. Lett. 1996, 687-688. (f) Rammo, J.; Hettich, R.; Roigk, A.; Schneider, H.-J. J. Chem. Soc., Chem. Commun. 1996, 105-107. (g) Hashimoto, S.; Nakamura, Y. J. Chem. Soc., Perkin Trans, 1 1996, 2623-2628.
8. Non-enzymatic scission of supercoiled plasmid DNA was reported: (a) Basile, L.A.; Raphael, A.L.; Barton, J.K. J. Am. Chem. Soc. 1987, 109, 7550-7551. (b) Schnaith, L.M.T.; Hanson, R.S.; Que, L., Jr. Proc. Natl. Acad. Sci. USA. 1994, 91, 569-573. (c) Dixon, N.E.; Geue, R.J.; Lambert, J.N.; Moghaddas, S.; Pearce, D.A.; Sargeson, A.M. J. Chem. Soc., Chem. Commun. 1996, 1287-1288. (d) Hegg, E.L.; Burstyn, J.N. Inorg. Chem. 1996, 35, 7474-7481. (e) Ihara, T.; Shimura, H.; Ohmori, K.; Tsuji, H.; Takeuchi, J.; Takagi, M. Chem. Lett. 1996, 687-688. (f) Rammo, J.; Hettich, R.; Roigk, A.; Schneider, H.-J. J. Chem. Soc., Chem. Commun. 1996, 105-107. (g) Hashimoto, S.; Nakamura, Y. J. Chem. Soc., Perkin Trans, 1 1996, 2623-2628.
9. Non-enzymatic scission of supercoiled plasmid DNA was reported: (a) Basile, L.A.; Raphael, A.L.; Barton, J.K. J. Am. Chem. Soc. 1987, 109, 7550-7551. (b) Schnaith, L.M.T.; Hanson, R.S.; Que, L., Jr. Proc. Natl. Acad. Sci. USA. 1994, 91, 569-573. (c) Dixon, N.E.; Geue, R.J.; Lambert, J.N.; Moghaddas, S.; Pearce, D.A.; Sargeson, A.M. J. Chem. Soc., Chem. Commun. 1996, 1287-1288. (d) Hegg, E.L.; Burstyn, J.N. Inorg. Chem. 1996, 35, 7474-7481. (e) Ihara, T.; Shimura, H.; Ohmori, K.; Tsuji, H.; Takeuchi, J.; Takagi, M. Chem. Lett. 1996, 687-688. (f) Rammo, J.; Hettich, R.; Roigk, A.; Schneider, H.-J. J. Chem. Soc., Chem. Commun. 1996, 105-107. (g) Hashimoto, S.; Nakamura, Y. J. Chem. Soc., Perkin Trans, 1 1996, 2623-2628.
10. Non-enzymatic scission of supercoiled plasmid DNA was reported: (a) Basile, L.A.; Raphael, A.L.; Barton, J.K. J. Am. Chem. Soc. 1987, 109, 7550-7551. (b) Schnaith, L.M.T.; Hanson, R.S.; Que, L., Jr. Proc. Natl. Acad. Sci. USA. 1994, 91, 569-573. (c) Dixon, N.E.; Geue, R.J.; Lambert, J.N.; Moghaddas, S.; Pearce, D.A.; Sargeson, A.M. J. Chem. Soc., Chem. Commun. 1996, 1287-1288. (d) Hegg, E.L.; Burstyn, J.N. Inorg. Chem. 1996, 35, 7474-7481. (e) Ihara, T.; Shimura, H.; Ohmori, K.; Tsuji, H.; Takeuchi, J.; Takagi, M. Chem. Lett. 1996, 687-688. (f) Rammo, J.; Hettich, R.; Roigk, A.; Schneider, H.-J. J. Chem. Soc., Chem. Commun. 1996, 105-107. (g) Hashimoto, S.; Nakamura, Y. J. Chem. Soc., Perkin Trans, 1 1996, 2623-2628.
11. Non-enzymatic scission of supercoiled plasmid DNA was reported: (a) Basile, L.A.; Raphael, A.L.; Barton, J.K. J. Am. Chem. Soc. 1987, 109, 7550-7551. (b) Schnaith, L.M.T.; Hanson, R.S.; Que, L., Jr. Proc. Natl. Acad. Sci. USA. 1994, 91, 569-573. (c) Dixon, N.E.; Geue, R.J.; Lambert, J.N.; Moghaddas, S.; Pearce, D.A.; Sargeson, A.M. J. Chem. Soc., Chem. Commun. 1996, 1287-1288. (d) Hegg, E.L.; Burstyn, J.N. Inorg. Chem. 1996, 35, 7474-7481. (e) Ihara, T.; Shimura, H.; Ohmori, K.; Tsuji, H.; Takeuchi, J.; Takagi, M. Chem. Lett. 1996, 687-688. (f) Rammo, J.; Hettich, R.; Roigk, A.; Schneider, H.-J. J. Chem. Soc., Chem. Commun. 1996, 105-107. (g) Hashimoto, S.; Nakamura, Y. J. Chem. Soc., Perkin Trans, 1 1996, 2623-2628.
12. Oxidative cleavage of DNA, in which the ribose residue, rather than the phosphodiester linkages as here, is cleaved, has been widely studied: a) ref. 2a. b) Sigman, D.S. Acc. Chem. Res. 1986, 19, 180-186 and references therein.
13. For metal-mediated hydrolysis of various activated phosphoesters, see Kimura, E.; Koike, T. in Advances in Inorganic Chemistry; Sykes, A.G., Ed.; Academic Press: New York, 1997; Vol.44, pp 229-261.
14. (a) Matsumoto, Y.; Komiyama, M. Nucleic Acids, Symp. Ser. 1992, 27, 33-34.
15. (b) Shiiba, T.; Yonezawa, K.; Takeda, N.; Matsumoto, Y.; Yashiro, M.; Komiyama, M. J. Mol. Catal. 1993, 84, L21-L25.
16. (c) Komiyama, M.; Matsumoto, Y.; Shiiba, T.; Hayashi, N.; Watanabe, K. Polym. J. 1993, 25, 1211-1214.
17. Komiyama, M.; Takeda, N.; Takahashi, Y.; Uchida, H.; Shiiba, T.; Kodama, T.; Yashiro, M. J. Chem. Soc., Perkin Trans. 2 1995, 269-274.
18. (b) Komiyama, M.; Shiiba, T.; Kodama, T.; Takeda, N.; Sumaoka, J.; Yashiro M. J. Biochem. 1994, 115, 809-810.
19. Takasaki, B.K.; Chin, J. J. Am. Chem. Soc. 1994, 116, 1121-1222.
20. Shigekawa, H.; Ikawa, H.; Yoshizaki, R.; Iijima, Y.; Sumaoka, J.; Komiyama, M. Appl. Phys. Lett. 1996, 68, 1433-1435.
21. Takeda, N.; Imai, T.; Irisawa, M.; Sumaoka, J.; Yashiro, M.; Komiyama, M. Chem. Lett., 1996, 599-600.
22. Sequence-selective and hydrolytic artificial restriction enzymes were prepared by attaching an iminodiacetate complex of Ce(IV) to DNA oligomers: (a) Komiyama, M.; Shiiba, T.; Takahashi, Y.; Takeda, N.; Matsumura, K.; Kodama T. Supramol. Chem., 1994, 4, 31-34. (b) Komiyama, M.; Takeda, N.; Shiiba, T.; Takahashi, Y.; Matsumoto, Y.; Yashiro, M. Nucleosides and Nucleotides, 1994, 13, 1297-1309.
23. Sequence-selective and hydrolytic artificial restriction enzymes were prepared by attaching an iminodiacetate complex of Ce(IV) to DNA oligomers: (a) Komiyama, M.; Shiiba, T.; Takahashi, Y.; Takeda, N.; Matsumura, K.; Kodama T. Supramol. Chem., 1994, 4, 31-34. (b) Komiyama, M.; Takeda, N.; Shiiba, T.; Takahashi, Y.; Matsumoto, Y.; Yashiro, M. Nucleosides and Nucleotides, 1994, 13, 1297-1309.
24. Bimetallic solutions of La(III)/Fe(III) system are homogeneous and hydrolyze linear DNA: Irisawa, M.; Komiyama, M. J. Biochem., 1995, 117, 465-466. However, the activity is not sufficient to hydrolyze DNA under physiological conditions.
25. Saccharide complexes of lanthanide (III) ions, other than of Ce(IV), were reported: (a) Angyal, S. J. Adv. Carbohydr. Chem. Biochem., 1989, 74, 1-43. (b) Israeli, Y.; Morel, J. P.; Morel-Desrosiers, N., Carbohydr. Res., 1994, 263, 25-33.
26. Saccharide complexes of lanthanide (III) ions, other than of Ce(IV), were reported: (a) Angyal, S. J. Adv. Carbohydr. Chem. Biochem., 1989, 74, 1-43. (b) Israeli, Y.; Morel, J. P.; Morel-Desrosiers, N., Carbohydr. Res., 1994, 263, 25-33.
27. -1, respectively. The hydrolysis of monophosphate are about 100 fold faster than that of TpT.
28. 0 is 1.0, homogeneous solutions are obtained for both the Ce(IV)/dextran and the Ce(IV)/Pr(III)/dextran systems. However, these solutions are rather unstable, and gradually become turbid and heterogeneous as the TpT hydrolysis proceeds. The ratio must be 2 or greater, in order to keep the mixtures homogeneous throughout the reactions.
29. -1, respectively.
30. None of amylose, poly(vinylalcohol), and poly(acrylic acid) provided homogeneous ternary solutions, which is consistent with the results for the binary systems.
31. a of the water bound to lanthanide(III) ions, other than Pr(III), is also between 7 and 9, and thus the corresponding metal-bound hydroxide is sufficiently basic for the catalysis: Burgess, J. Metal Ions in Solution, Horwood, 1978, Chichester).