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Volumn 122, Issue 29, 2000, Pages 7140-7141

Lead poisoning and the inactivation of 5-aminolevulinate dehydratase as modeled by the tris(2-mercapto-1-phenylimidazolyl)hydroborato lead complex, {[Tm(Ph)]Pb}[ClO4] [14]

Author keywords

[No Author keywords available]

Indexed keywords

BORIC ACID; IMIDAZOLE DERIVATIVE; LEAD; METAL COMPLEX; PORPHOBILINOGEN SYNTHASE;

EID: 0034718069     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja001530y     Document Type: Letter
Times cited : (126)

References (43)
  • 9
    • 0343100581 scopus 로고    scopus 로고
    • note
    • ALAD is also known as porphobilinogen synthase (PBGS).
  • 21
    • 0342666243 scopus 로고    scopus 로고
    • note
    • It should be noted that ALAD enzymes contain more than one type of metal binding site. For further discussion of structures of the various sites, see ref 5.
  • 23
    • 29444451111 scopus 로고    scopus 로고
    • Probing of Proteins by Metal Ions and Their Low-Molecular-Weight Complexes
    • Sigel. A., Sigel, H., Eds.; M. Dekker: New York, in press
    • Parkin, G. Probing of Proteins by Metal Ions and Their Low-Molecular-Weight Complexes. In Metal Ions in Biological Systems; Sigel. A., Sigel, H., Eds.; M. Dekker: New York, 2000; Vol. 38, in press.
    • (2000) Metal Ions in Biological Systems , vol.38
    • Parkin, G.1
  • 25
    • 0343972370 scopus 로고    scopus 로고
    • note
    • 2 in MeCN and has been structurally characterized by X-ray diffraction. See Supporting Information.
  • 26
    • 0343923843 scopus 로고    scopus 로고
    • note
    • Furthermore, the Pb⋯Pb separation of 3.99 Å is significantly greater than twice the covalent radius of lead (3.08 Å).
  • 28
    • 0001580934 scopus 로고    scopus 로고
    • (a) Parr, J. Polyhedron 1997, 16, 551-566.
    • (1997) Polyhedron , vol.16 , pp. 551-566
    • Parr, J.1
  • 34
    • 0343923841 scopus 로고    scopus 로고
    • Cambridge Structural Database (version 5.18)
    • Cambridge Structural Database (version 5.18). 3D Search and Research Using the Cambridge Structural Database: Allen, F. H.; Kennard, O. Chemical Design Automation News 1993, 8 (1), pp 1, 31-37.
    • 3D Search and Research Using the Cambridge Structural Database
  • 35
    • 0002087304 scopus 로고
    • Cambridge Structural Database (version 5.18). 3D Search and Research Using the Cambridge Structural Database: Allen, F. H.; Kennard, O. Chemical Design Automation News 1993, 8 (1), pp 1, 31-37.
    • (1993) Chemical Design Automation News , vol.8 , Issue.1 , pp. 1
    • Allen, F.H.1    Kennard, O.2
  • 36
    • 0343052165 scopus 로고    scopus 로고
    • note
    • Ph]Pb} [2.693(2) Å].
  • 38
    • 0343052167 scopus 로고    scopus 로고
    • note
    • "Hemidirected" geometries are those in which the ligands are distributed over only a portion of the coordination sphere, while "holodirected" geometries are those in which the ligands are distributed more evenly about the whole surface of the coordination sphere. See ref 18.
  • 39
    • 0343487978 scopus 로고    scopus 로고
    • note
    • -1 higher in energy than the tetrahedral structure. See ref 18.
  • 41
    • 0343923839 scopus 로고    scopus 로고
    • note
    • Zn to be determined.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.