Differential activation of MAP kinase signaling pathways and nuclear factor-κB in bronchoalveolar cells of smokers and nonsmokers

Molecular Medicine

Volumn 7, Issue 3, 2001, Pages 177-185

  Mochida Nishimura, Keiko ^a,c   Surewicz, Krystyna ^a   Cross, Janet V ^b   Hejal, Rana ^a   Templeton, Dennis ^b   Rich, Elizabeth A ^a   Toossi, Zahra ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA;

ADULT; ARTICLE; BRONCHUS; CASE CONTROL STUDY; CYTOLOGY; DNA PROBE; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; HUMAN; LUNG ALVEOLUS; METABOLISM; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION; SMOKING;

ADULT; BASE SEQUENCE; BRONCHI; CASE-CONTROL STUDIES; DNA PROBES; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HUMANS; I-KAPPA B PROTEINS; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PULMONARY ALVEOLI; SMOKING;

EID: 0035294522     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03401951     Document Type: Article

References (54)

1. Drath DB, Davies P, Karnovsky ML, Huber GL. (1979) Tobacco smoke and the pulmonary alveolar macrophages. Adv Exp Med Biol. 121: 555-568.
2. Nieman RB, Fleming J, Coker RJ, Harris JRW, Mitchell DM. (1993) The effect of cigarette smoking on the development of AIDS in HIV-1 seropositive individuals. AIDS 1: 705-710.
3. Hunter T, Karin M. (1992) The regulation of transcription by phosphorylation. Cell 70: 375-387.
4. Davis RJ. (1993) The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem 268: 14553-14556.
5. Hill CS, Treisman R. (1995) Transcriptional regulation by extracellular signal: mechanisms and specificity. Cell 80: 199-211.
6. Suzuki YJ, Mizuno M, Packer L. (1994) Signal transduction for nuclear factor-κB activation. J. Immunol 153: 5008-5015.
7. Karin M. (1999) The beginning of the end: IκB kinase (IKK) and NF-κB activation. J. Biol. Chem. 274: 27339-27342.
8. Siebenlist U, Franzoso G, Brown K. (1994) Structure, regulation and function of NF-κB. Annu. Rev. Cell Biol. 10: 405-455.
9. Lee FS, Peters RT, Dang LC, Maniatis T. (1998) MEKK1 activates both IκB kinase a and IκB kinase b. Proc. Natl. Acad Sci USA 95: 9319-9324.
10. Meyer CF, Wang X, Chang C, Templeton D, Tan TH. (1996) Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating κB enhancer activation. J Biol. Chem. 271: 8971-8976.
11. Baughman RP, Corser BC, Strohofer S, Hendricks D. (1986) Spontaneous hydrogen peroxide release from alveolar macrophages of some cigarette smokers. J. Lab Clin Med. 107: 233-237.
12. Ogura M, Kitamura M. (1998) Oxidant stress incites spreading of macrophages via extracellular signal-regulated kinase and p38 mitogen-activated protein kinase. J Immunol 161: 3569-3574.
13. Heusch WL, Maneckjee R. (1998) Signalling pathways involved in nicotine regulation of apoptosis of human lung cancer cells. Carcinogenesis 19: 551-556.
14. Geng Y, Savage SM, Razanai-Boroujerdi S, Sopori ML. (1996) Effect of nicotine on the immune response. II. Chronic nicotine treatment induces T cell anergy. J. Immunol. 156: 2384-2390.
15. Almirall J, Bolibar I, Balanzo X, Gonzalez CA. (1999) Risk factors for community-acquired pneumonia in adults: a population-based case-control study. Eur. Respir. J. 13: 349-55.
16. Abbud R, Finegan CK, Guay LA, Rich EA. (1995) Enhanced production of human immunodeficiency virus type 1 by in vitro-infected alveolar macrophages from otherwise healthy cigarette smokers. J Infect Dis. 172: 859-63.
17. Swingler S, Morria A, Easton A. (1994) Tumour necrosis factor alpha and interleukin-1 beta induce specific subunits of NF-κB to bind the HIV-1 enhancer: characterisation of transcription factors controlling human immunodeficiency virus type 1 gene expression in neural cell. Biochem. Biophys Res Commun. 203: 623-30.
18. Hirsch CJ, Ellner JJ, Rusell DG, Rich EA. (1994) Complement receptor mediated uptake and tumor necrosis-a mediated growth inhibition of Mycobacterium tuberculosis by human alveolar macrophages. J Immunol 152: 743-753.
19. Li CY, Lam KW, Yam LT. (1973) Esterases in human leukocytes. J. Histochem Cytochem 21: 1-4.
20. Schreiber E, Matthias P, Muller MM, Schaffner W. (1989) Rapid detection of octamer binding protein with 'mini-extracts' prepared from a small number of cells. Nucleic Acid Res. 17: 6419.
21. Berkhout B, Kuan-Ten J. (1992) Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat. J. Virol 66: 139-149.
22. Cross JV, Deak JC, Rich EA, Mochida K, Templeton DJ. (1999) Quinone reductase inhibitors block SAPK/JNK and NF-κB pathways and potentiate apoptosis. J. Biol. Chem 44: 31150-31154.
23. Xu YL, Adya N, Siores E, Gao Q, Giam CZ. (1990) Cellular factors involved in transcription and Tax-mediated transactivation directed by the TGACGT motifs in human T-cell leukemia virus type 1 promoter. J Biol. Chem 33: 20285-20292.
24. Laemmli UK. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-686.
25. Towbin H, Staehelin T, Gordon J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad Sci USA 76: 4350-4353.
26. Deak JC, Cross JV, Lewis M, Qian Y, Distelhorst CW, Templeton DJ. (1998) FAS-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1. Proc. Natl. Acad. Sci. USA 95: 5595-5600.
27. Schreck R, Rieber P, Baeuerle PA. (1991) Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. EMBO J. 10: 2247-2258.
28. Krejsa CM, Nadler SG, Esselstyn JM, Kavanagh TJ, Ledbetter JA, Schieven GL. (1997) Role of oxidative stress in the action of vanadium phosphotyrosine phosphatase inhibitors. J Biol. Chem 272: 11541-11549.
29. Hoidal JR, Niewoehner DE. (1982) Lung phagocytes recruitment and metabolic alterations induced by cigarette smoking in human and hamsters. Am Rev Respir Dis 126: 548-552.
30. Martin RR. (1973) Altered morphology and increased acid hydrolase content of pulmonary macrophages from cigarette smokers. Am. Rev. Respir. Dis. 107: 596-601.
31. Hubbard RC. (1987) Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase. J Clin. Invest. 80: 1289-1295.
32. Kondo T, Tagami S, Yoshioka A, Nishimura M, Kawakami Y. (1994) Current smoking of elderly men reduces antioxidants in alveolar macrophages. Am J. Resptr. Crit Care Med. 149: 178-182.
33. Skold CM, Lundahl J, Hallden G, Hallgren M, Eklund A. (1996) Chronic smoke exposure alters the phenotype pattern and the metabolic response in human alveolar macrophages. Clin. Exp Immunol 106: 108-113.
34. Thomassen MJ, Barna BP, Wiedemann HP, Farmer M, Ahmad M. (1988) Human alveolar macrophages function: differences between smokers and nonsmokers. J Leukec Biol 44: 313-318.
35. Teramoto S, Uejima Y, Teramoto K, Ouchi Y, Fukuchi Y. (1996) Effect of age on alteration of glutathione metabolism following chronic cigarette smoke inhalation In mice. Lung 174: 119-126.
36. DiSilvestro RA, Pacht E, Davis B, Jarjour N, Joung H, Trela-Fulop K. (1998) BAL fluid contains detectable Superoxide dismutase 1 activity. Chest 113: 401-404.
37. Hilbert J, Mohsenin V. (1996) Adaptation of lung antioxidants to cigarette smoking in humans. Chest 110: 916-920.
38. Melloni B, Lefebvre MA, Bonnaud F, Vergnenegre A, Grossin L, Rigaug M, Cantin A. (1996) Antioxidant activity in bronchoalveolar lavage fluid from patients with lung cancer. Am. J Respir. Crit. Care Med 154: 1706-1711.
39. Wurzel H, Yeh CC, Gairola C, Chow CK. (1995) Oxidative damage and antioxidant status in the lungs and bronchoalveolar lavage fluid of rats exposed chronically to cigarette smoke. J. Biochem Toxicol 10: 11-17.
40. Feng GJ, Goodridge HS, Harnett MM, Wei XQ, Nikolaev AV, Higson AP, Liew FY. (1999) Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase. J. Immunol. 163: 6403-6412.
41. Matthews JS, O'Neill LAJ. (1999) Distinct roles for p42/p44 and p38 mitogen-activated protein kinases in the induction of IL-2 by IL-1. Cytokine 9: 643-655.
42. Jun CD, Oh CD, Kwak HJ, et al. (1999) Overexpression of protein kinase C isoforms protects RAW 264.7 macrophages from nitric oxide-induced apoptosis: involvement of c-Jun N-terminal kinase/stress-activated protein kinase, p38 kinase, and CPP-32 protease pathways. J. Immunol. 162: 3395-3401.
43. Shrifin VI, Anderson P. (1999) Trichothecene mycotoxins trigger a ribotoxic stress response that activates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase and induces apoptosis. J Biol. Chem. 274: 13985-13992.
44. Bingisser R, Stey C, Weller M, Groscurth P, Russi E, Frei K. (1996) Apoptosis in human alveolar macrophages is induced by endotoxin and is modulated by cytokines. Am. J. Respir Cell Mol. Biol 1: 64-70.
45. Arbabi S, Garcia I, Bauer GJ, Maier RV. (1999) Alcohol (ethanol), inhibits IL-8 and TNF: role of the p38 pathway. J Immunol. 162: 7441-7445.
46. Kitchens R. (2000) Role of CD14 in cellular recognition of bacterial lipopolysaccharides. Chem. Immunol. 74: 61-82.
47. Procyk KJ, Kovarik P, von Gabain A, Baccarini M. (1998) Salmonella typhimurium and lipopolysaccharide stimulate extracellularly kinase activation in macrophages by a mechanism involving phosphatidylinositol 3-kinase and phospholipase D as novel intermediates. Infect. Immun. 67: 1011-1017.
48. Scherle PA, Jones EA, Favata MF, et al. (1998) Inhibition of MAP kinase kinase prevents cytokine and prostoglandin E2 production in lipopolysaccharide stimulated monocytes. J. Immunol 161: 5681-5686.
49. Monick MM, Carter BA, Gudmundsson G, Geist LJ, Hunninghake GW, (1998) Changes in PKC isoforms in human alveolar macrophages compared with blood monocytes. Am. J. Phystol. 275: L389-397.
50. Toossi Z, Hirsch CS, Hamilton BD, Knuth CK, Friedlander MA, Rich EA. (1996) Decreased production of TGF-beta 1 by human alveolar macrophages compared with blood monocytes. Immunology 156: 3461-3468.
51. Biggs TE, Cooke SJ, Barton CH, Harris MP, Saksela K, Mann DA. (1999) Induction of activator protein 1 (AP-1) in macrophages by human immunodeficiency virus type-1 NEF is a cell-type-specific response that requires both hck and MAPK signaling events. Mol Biol. 290: 21-35.
52. Yan X, Chen Y, Gabuzda D. (1999) ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-kappaB. J. Biol. Chem. 274: 27981-27988.
53. Popik W, Hesselgesser JE, Pitha PM. (1998) Binding of human immunodeficiency virus type1 to CD4 and CXCR4 receptor differentially regulates expression of inflammatory genes and activates the MEK/ERK. signaling pathway. J. Virol. 72: 6406-6413.
54. Sebolt-Leopold JS, Dudley DT, Herrera R, et al. (1999) Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat. Med. 5: 810-816.