Adaptation of lung antioxidants to cigarette smoking in humans

Chest

Volumn 110, Issue 4, 1996, Pages 916-920

  Hilbert, Janet ^a   Mohsenin, Vahid ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHN B PIERCE LABORATORY   (United States)

Author keywords

catalase; glutathione; lung antioxidants; peroxidase; superoxide dismutase; vitamin C; vitamin E; carotene

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; CATALASE; GLUTATHIONE PEROXIDASE; PLACEBO; SCAVENGER; SUPEROXIDE DISMUTASE; VITAMIN;

ADAPTATION; ADULT; ARTICLE; CIGARETTE SMOKING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG CAPSULE; ENZYME ACTIVITY; HOST RESISTANCE; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; LUNG INJURY; LUNG LAVAGE; PRIORITY JOURNAL; SINGLE BLIND PROCEDURE; VITAMIN BLOOD LEVEL;

EID: 0029962621     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.110.4.916     Document Type: Article

References (34)

1. Janoff A. Elastases and emphysema: current assessment of the protease-antiprotease hypothesis. Am Rev Respir Dis 1985; 132:417-33
2. Cantin AM, Crystal RG. Oxidants, antioxidants and the pathogenesis of emphysema. Eur J Respir Dis 1985; 66(suppl 139):7-17
3. Hoidal JR, Niewoehner DE. Lung phagocyte recruitment and metabolic alterations induced by cigarette smoke in humans and hamsters. Am Rev Respir Dis 1982; 126:548-52
4. Hunningshake GW, Crystal RG. Cigarette smoking and lung destruction: accumulation of neutrophils in the lungs of cigarette smokers. Am Rev Respir Dis 1983; 128:833-39
5. Hoidal JR, Fox RB, LeMarbe PA, et al. Altered oxidative metabolic responses in vitro of alveolar macrophages from asymptomatic cigarette smokers. Am Rev Respir Dis 1981; 123:85-9
6. Drath DB, Karnovsky ML, Huber GL. The effects of experimental exposure to tobacco smoke on the oxidative metabolism of alveolar macrophages. J Reticuloendothelial Soc 1970; 25:597-604
7. Church DF, Pryor WA. Free-radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect 1985; 64:111-26
8. Pryor WA, Prier DO, Church DF. Electron-spin resonance study of mainstream and sidestream cigarette smoke: nature of the free radicals in gas-phase smoke and cigarette tar. Environ Health Perspect 1983; 47:345-55
9. Pryor WA, Dooley MD, Church DF. The mechanisms of inacrivation of human alpha-1-proteinase inhibitor by gas phase cigarette smoke. Adv Free Radical Biol Med 1986; 2:161-88
10. Hubbard RC, Ogustin F, Fells GA, et al. Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha-1 -antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase. J Clin Invest 1987; 80: 1289-95
11. Schwalb G, Anderson R. Increased frequency of oxidant-mediated DNA strand breaks in mononuclear leucocytes exposed to activated neutrophils from cigarette smokers. Mutat Res 1989; 225:95-9
12. Niewoehner DE, Kleinerman J, Rice DB. Pathologic changes in the peripheral airways of young cigarette smokers. N Engl J Med 1974; 291:755-58
13. Petruzzelli S, Hietanen E, Bartsch H, et al. Pulmonary lipid peroxidation in cigarette smokers and lung cancer patients. Chest 1990; 98:930-35
14. Shariff R, Hoshino E, Allard J, et al. Vitamin E supplementation in smokers [abstract]. Am J Clin Nutr 1988; 47:758
15. McCusker K, Hoidal J. Selective increase of antioxidant enzyme activity in alveolar macrophages from cigarette smokers and smoke-exposed hamsters. Am Rev Hespir Dis 1990; 141:678-82
16. Cantin AM, North SL, Hubbard RC, et al. Normal alveolar epithelial lining fluid contains high levels ot glutathione. J Appl Physiol 1987; 63:152-57
17. Toth KM, Berger EM, Beehler CJ, et al. Erythrocytes from cigarette smokers contain more glutathione and catalose and protect endothelial cells trom hydrogen peroxide better than do erythrocytes from nonsmokers. Am Rev Respir Dis 1986; 134:281-84
18. Mohsenin V, Gee JBL. Acute effect of nitrogen dioxide exposure on the functional activity of alpha-1-protease inhibitor in bronchoalveolar lavage fluid of normal subjects. Am Rev Respir Dis 1987; 136:646-50
19. Elstner EF, Youngman RJ, Obwald W. Superoxide dismutase. In: Moss DW, ed. Methods of enzymatic analysis: enzyme 1: oxidoreductases, transferases. Deerfield Beach, Fla: VCH Publishers, 1983; 293-302
20. Beers RF, Sizer IW. A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem 1952; 195:133-40
21. Paglia DE, Valentine WN, Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967; 70:158-69
22. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 1976; 72:248-54
23. Omaye ST, Turnbull JD, Sauberlich HE. Selected methods for determination of ascorbic acid in animal cells, tissues, and fluids. Methods Enzymol 1979; 62:3-11
24. Craft NE, Brown ED, Smith JC. Effects of storage and handling conditions on concentrations of individual carotenoids, retinol and α-tocopherol in plasma. Clin Chem 1988; 34:44-8
25. Chow CK, Thacker RR, Changchit C, et al. Lower levels of vitamin C and carotenes of plasma of cigarette smokers. J Am Coll Nutr 1986; 5:305-12
26. Comstock GW, Menkes MS, Schober SE, et al. Serum levels of retinol, β-carotene, and alpha-tocopherol in older adults. Am J Epidemiol 1988; 127:114-23
27. Nishild K, Jamieson D, Oshino N, et al. Oxygen toxicity in the perfused rat liver and lung under hyperbaric conditions. Biochem J 1976; 160:343-55
28. Pacht ER, Kaseki H, Mohammed JR, et al. Deficiency of vitamin E in the alveolar fluid of cigarette smokers: influence on alveolar macrophage cytotoxicity. J Clin Invest 1986; 77:789-96
29. Elsayed NM. Mobilization of vitamin E to the lung under oxidative stress. Ann NY Acad Sci 1989; 570:439-40
30. Airriess GR, Chagchitt C, Chen L-C, et al. Increased vitamin E levels in the lungs of guinea pigs exposed to mainstream smoke. Nutr Res 1988;8:653-61
31. McGowan SE, Parenti CM, Hoidal JR, et al. Ascorbic acid accumulation by alveolar macrophages from cigarette smokers and nonsmokers. J Lab Clin Med 1984; 104:127-34
32. Jornot L, Junod AF. Response of human endothelial cell antioxidant enzymes to hyperoxia. Am J Respir Cell Mol Biol 1992; 6:107-15
33. Rushmore TH, Morton MR, Pickett CB. The antioxidant responsive element: activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem 1991; 266:11632-39
34. Duthie GG, Arthur JR, James WPI, et al. Antioxidant status of smokers and nonsmokers: effect of vitamin E supplementation. Ann NY Acad Sci 1989; 570:435-38