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Volumn 56, Issue 1-2, 1998, Pages 169-177

Increased expression of amyloid precursor protein and amyloid precursor-like protein 2 during trophic factor withdrawal-induced death of neuronal PC12 cells

Author keywords

Alzheimer's disease; Amyloid precursor protein; Amyloid precursor like protein 2; Apoptosis; Programmed cell death

Indexed keywords

AMYLOID PRECURSOR LIKE PROTEIN 2; AMYLOID PRECURSOR PROTEIN; BASIC FIBROBLAST GROWTH FACTOR; DNA FRAGMENT; MESSENGER RNA; NERVE GROWTH FACTOR; PROTEIN; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 0032077640     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(98)00050-3     Document Type: Article
Times cited : (26)

References (57)
  • 1
    • 0025845529 scopus 로고
    • Induction of amyloid precursor protein mRNA after heat shock in cultured human lymphoblastoid cells
    • Abe K., St. George-Hyslop P.H., Tanzi R.E., Kogure K. Induction of amyloid precursor protein mRNA after heat shock in cultured human lymphoblastoid cells. Neurosci. Lett. 125:1991;169-171.
    • (1991) Neurosci. Lett. , vol.125 , pp. 169-171
    • Abe, K.1    St. George-Hyslop, P.H.2    Tanzi, R.E.3    Kogure, K.4
  • 2
    • 0025775107 scopus 로고
    • Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex
    • Abe K., Tanzi R.E., Kogure K. Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex. Neurosci. Lett. 125:1991;172-174.
    • (1991) Neurosci. Lett. , vol.125 , pp. 172-174
    • Abe, K.1    Tanzi, R.E.2    Kogure, K.3
  • 3
    • 0025970571 scopus 로고
    • Increased gene expression of Alzheimer disease β-myloid precursor protein in senescent cultured fibroblasts
    • Adler M.J., Coronel C., Shelton E., Seegmiller J.E., Dewji N.N. Increased gene expression of Alzheimer disease β-myloid precursor protein in senescent cultured fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 88:1991;16-20.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 16-20
    • Adler, M.J.1    Coronel, C.2    Shelton, E.3    Seegmiller, J.E.4    Dewji, N.N.5
  • 4
    • 0028210761 scopus 로고
    • Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: Association with pathology
    • Anderson A.J., Cummings B.J., Cotman C.W. Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: association with pathology. Exp. Neurol. 125:1994;286-295.
    • (1994) Exp. Neurol. , vol.125 , pp. 286-295
    • Anderson, A.J.1    Cummings, B.J.2    Cotman, C.W.3
  • 5
    • 0029976253 scopus 로고    scopus 로고
    • DNA damage and apoptosis in Alzheimer's disease: Colocalization with c-jun immunoreactivity, relationship to brain area, and effect of postmortem delay
    • Anderson A.J., Su J.H., Cotman C.W. DNA damage and apoptosis in Alzheimer's disease: colocalization with c-jun immunoreactivity, relationship to brain area, and effect of postmortem delay. J. Neurosci. 16:1996;1710-1719.
    • (1996) J. Neurosci. , vol.16 , pp. 1710-1719
    • Anderson, A.J.1    Su, J.H.2    Cotman, C.W.3
  • 7
    • 0028181164 scopus 로고
    • Demonstration of amyloid β-protein secretion in a mouse neuronal cell line
    • Araki W., Kunishita T., Takahashi K., Ikeda S., Tabira T. Demonstration of amyloid β-protein secretion in a mouse neuronal cell line. Neurosci. Lett. 167:1994;125-127.
    • (1994) Neurosci. Lett. , vol.167 , pp. 125-127
    • Araki, W.1    Kunishita, T.2    Takahashi, K.3    Ikeda, S.4    Tabira, T.5
  • 8
    • 0028176153 scopus 로고
    • Role of the β-amyloid precursor protein in Alzheimer's disease
    • Ashall F., Goate A.M. Role of the β-amyloid precursor protein in Alzheimer's disease. Trends Biochem. Sci. 19:1994;42-46.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 42-46
    • Ashall, F.1    Goate, A.M.2
  • 9
    • 0025965521 scopus 로고
    • Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion
    • Breen K.C., Bruce M., Anderton B.H. Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion. J. Neurosci. Res. 28:1991;90-100.
    • (1991) J. Neurosci. Res. , vol.28 , pp. 90-100
    • Breen, K.C.1    Bruce, M.2    Anderton, B.H.3
  • 10
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • ChoMcZynski, P.1    Sacchi, N.2
  • 11
    • 0029888642 scopus 로고    scopus 로고
    • Nerve growth factor and Ras regulate β-amyloid precursor protein gene expression in PC12 cells
    • Cosgaya J.M., Latasa M.J., Pascual A. Nerve growth factor and Ras regulate β-amyloid precursor protein gene expression in PC12 cells. J. Neurochem. 67:1996;98-104.
    • (1996) J. Neurochem. , vol.67 , pp. 98-104
    • Cosgaya, J.M.1    Latasa, M.J.2    Pascual, A.3
  • 12
    • 0029245289 scopus 로고
    • A potential role for apoptosis in neurodegeneration and Alzheimer's disease
    • Cotman C.W., Anderson A.J. A potential role for apoptosis in neurodegeneration and Alzheimer's disease. Mol. Neurobiol. 10:1995;19-45.
    • (1995) Mol. Neurobiol. , vol.10 , pp. 19-45
    • Cotman, C.W.1    Anderson, A.J.2
  • 13
    • 0028983336 scopus 로고
    • Amyloid β-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells
    • Davis-Salinas J., Saporito-Irwin S.M., Cotman C.W., Van Nostrand W.E. Amyloid β-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells. J. Neurochem. 65:1995;931-934.
    • (1995) J. Neurochem. , vol.65 , pp. 931-934
    • Davis-Salinas, J.1    Saporito-Irwin, S.M.2    Cotman, C.W.3    Van Nostrand, W.E.4
  • 15
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Green L.A., Tischler A.S. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. U.S.A. 73:1976;2424-2428.
    • (1976) Proc. Natl. Acad. Sci. U.S.A. , vol.73 , pp. 2424-2428
    • Green, L.A.1    Tischler, A.S.2
  • 17
    • 0027443562 scopus 로고
    • + channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid precursor genes and neuronal death in rat hippocampus
    • + channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid precursor genes and neuronal death in rat hippocampus. Proc. Natl. Acad. Sci. U.S.A. 90:1993;9431-9435.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 9431-9435
    • Heurteaux, C.1    Bertaina, V.2    Widmann, C.3    Lazdunski, M.4
  • 18
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson M.D., Weil M., Raff M.C. Programmed cell death in animal development. Cell. 88:1997;347-354.
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 19
    • 0030771534 scopus 로고    scopus 로고
    • Increased apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin-2 mutation (N141I)
    • Janicki S., Monteiro M.J. Increased apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin-2 mutation (N141I). J. Cell Biol. 139:1997;485-495.
    • (1997) J. Cell Biol. , vol.139 , pp. 485-495
    • Janicki, S.1    Monteiro, M.J.2
  • 20
    • 0028136865 scopus 로고
    • Peptides containing the RERMS sequence of amyloid β/A4 protein precursor bind cell surface and promote neurite extension
    • Jin L.-W., Ninomiya H., Roch J.-M., Schubert D., Masliah E., Otero D.A.C., Saitoh T. Peptides containing the RERMS sequence of amyloid β/A4 protein precursor bind cell surface and promote neurite extension. J. Neurosci. 14:1994;5461-5470.
    • (1994) J. Neurosci. , vol.14 , pp. 5461-5470
    • Jin, L.-W.1    Ninomiya, H.2    Roch, J.-M.3    Schubert, D.4    Masliah, E.5    Otero, D.A.C.6    Saitoh, T.7
  • 21
    • 0027202676 scopus 로고
    • Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks β/A4 amyloid immunoreactivity
    • Kametani F., Tanaka K., Ishii T., Ikeda S., Kennedy H.E., Allsop D. Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks β/A4 amyloid immunoreactivity. Biochem. Biophys. Res. Commun. 191:1993;392-398.
    • (1993) Biochem. Biophys. Res. Commun. , vol.191 , pp. 392-398
    • Kametani, F.1    Tanaka, K.2    Ishii, T.3    Ikeda, S.4    Kennedy, H.E.5    Allsop, D.6
  • 23
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implication in tissue kinetics
    • Kerr J.F.R., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implication in tissue kinetics. Br. J. Cancer. 26:1972;239-257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 24
    • 0030868903 scopus 로고    scopus 로고
    • Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease
    • Kim T.-W., Pettingell W.H., Jung Y.-K., Kovacs D.M., Tanzi R.E. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease. Science. 277:1997;373-376.
    • (1997) Science , vol.277 , pp. 373-376
    • Kim, T.-W.1    Pettingell, W.H.2    Jung, Y.-K.3    Kovacs, D.M.4    Tanzi, R.E.5
  • 25
    • 0023872043 scopus 로고
    • Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity
    • Kitaguchi N., Takahashi Y., Tokushima Y., Shiojiri S., Ito H. Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature. 331:1988;530-532.
    • (1988) Nature , vol.331 , pp. 530-532
    • Kitaguchi, N.1    Takahashi, Y.2    Tokushima, Y.3    Shiojiri, S.4    Ito, H.5
  • 26
    • 0028981717 scopus 로고
    • The Alzheimer's A beta peptide induces neurodegradation and apoptotic cell death in transgenic mice
    • LaFerla F.M., Tinkle B.T., Bieberich C.J., Haudenschild C.C., Jay G. The Alzheimer's A beta peptide induces neurodegradation and apoptotic cell death in transgenic mice. Nat. Genet. 9:1995;21-30.
    • (1995) Nat. Genet. , vol.9 , pp. 21-30
    • Laferla, F.M.1    Tinkle, B.T.2    Bieberich, C.J.3    Haudenschild, C.C.4    Jay, G.5
  • 29
    • 0030924310 scopus 로고    scopus 로고
    • Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation
    • Lee R.K.K., Araki W., Wurtman R.J. Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation. Proc. Natl. Acad. Sci. U.S.A. 94:1997;5422-5426.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 5422-5426
    • Lee, R.K.K.1    Araki, W.2    Wurtman, R.J.3
  • 31
    • 0027478347 scopus 로고
    • Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein
    • Mattson M.P., Cheng B., Culwell A.R., Esch F.S., Lieberburg I., Rydel R.E. Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein. Neuron. 10:1993;243-254.
    • (1993) Neuron , vol.10 , pp. 243-254
    • Mattson, M.P.1    Cheng, B.2    Culwell, A.R.3    Esch, F.S.4    Lieberburg, I.5    Rydel, R.E.6
  • 32
    • 0027071804 scopus 로고
    • Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons
    • Mesner P.W., Winters T.R., Green S.H. Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons. J. Cell Biol. 119:1992;1669-1680.
    • (1992) J. Cell Biol. , vol.119 , pp. 1669-1680
    • Mesner, P.W.1    Winters, T.R.2    Green, S.H.3
  • 33
    • 0028839253 scopus 로고
    • A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells
    • Mesner P.W., Epting C.L., Hegarty J.L., Green S.H. A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells. J. Neurosci. 15:1995;7357-7366.
    • (1995) J. Neurosci. , vol.15 , pp. 7357-7366
    • Mesner, P.W.1    Epting, C.L.2    Hegarty, J.L.3    Green, S.H.4
  • 34
    • 0026663993 scopus 로고
    • The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth
    • Milward E.A., Papadopoulos R., Fuller S.J., Moir R.D., Small D., Beyreuther K., Masters C.L. The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth. Neuron. 9:1992;129-137.
    • (1992) Neuron , vol.9 , pp. 129-137
    • Milward, E.A.1    Papadopoulos, R.2    Fuller, S.J.3    Moir, R.D.4    Small, D.5    Beyreuther, K.6    Masters, C.L.7
  • 35
    • 0025939423 scopus 로고
    • Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms
    • Rukenstein A., Rydel R.E., Greene L.A. Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms. J. Neurosci. 11:1991;2552-2563.
    • (1991) J. Neurosci. , vol.11 , pp. 2552-2563
    • Rukenstein, A.1    Rydel, R.E.2    Greene, L.A.3
  • 37
    • 0028064941 scopus 로고
    • Complete nucleotide and deduced amino acid sequence of rat amyloid protein precursor-like protein 2 (APLP2/APPH): Two amino acids length difference to human and murine homologues
    • Sandbrink R., Masters C.L., Beyreuther K. Complete nucleotide and deduced amino acid sequence of rat amyloid protein precursor-like protein 2 (APLP2/APPH): two amino acids length difference to human and murine homologues. Biochim. Biophys. Acta. 1219:1994;167-170.
    • (1994) Biochim. Biophys. Acta , vol.1219 , pp. 167-170
    • Sandbrink, R.1    Masters, C.L.2    Beyreuther, K.3
  • 38
    • 0024810385 scopus 로고
    • The regulation of amyloid β protein precursor secretion and its modulatory role in cell adhesion
    • Schubert D., Jin L.-W., Saitoh T., Cole G. The regulation of amyloid β protein precursor secretion and its modulatory role in cell adhesion. Neuron. 3:1989;689-694.
    • (1989) Neuron , vol.3 , pp. 689-694
    • Schubert, D.1    Jin, L.-W.2    Saitoh, T.3    Cole, G.4
  • 39
    • 0029784838 scopus 로고    scopus 로고
    • Amyloid β-protein and the genetics of Alzheimer's disease
    • Selkoe D.J. Amyloid β-protein and the genetics of Alzheimer's disease. J. Biol. Chem. 271:1996;18295-18298.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18295-18298
    • Selkoe, D.J.1
  • 40
    • 0024005801 scopus 로고
    • Alzheimer's disease amyloidogenic glycoprotein: Expression pattern in rat brain suggests a role in cell contact
    • Shivers B.D., Hilbich C., Multhaup G., Salbaum M., Beyreuther K., Seeburg P.H. Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact. EMBO J. 7:1988;1365-1370.
    • (1988) EMBO J. , vol.7 , pp. 1365-1370
    • Shivers, B.D.1    Hilbich, C.2    Multhaup, G.3    Salbaum, M.4    Beyreuther, K.5    Seeburg, P.H.6
  • 41
    • 0027474159 scopus 로고
    • NGF deprivation and neuronal degeneration trigger altered β-amyloid precursor protein gene expression in the rat superior cervical ganglia in vivo and in vitro
    • Smith C.J., Johnson E.M. Jr., Osborne P., Freeman R.S., Neveu I., Brachet P. NGF deprivation and neuronal degeneration trigger altered β-amyloid precursor protein gene expression in the rat superior cervical ganglia in vivo and in vitro. Mol. Brain Res. 17:1993;328-334.
    • (1993) Mol. Brain Res. , vol.17 , pp. 328-334
    • Smith, C.J.1    Johnson E.M., Jr.2    Osborne, P.3    Freeman, R.S.4    Neveu, I.5    Brachet, P.6
  • 42
    • 0027393439 scopus 로고
    • Increased levels of the Kunitz protease inhibitor-containing βAPP mRNAs in rat brain following neurotoxic damage
    • Sola C., Garcia-Ladona F.J., Mengod G., Probst A., Frey P., Palacios J.M. Increased levels of the Kunitz protease inhibitor-containing βAPP mRNAs in rat brain following neurotoxic damage. Mol. Brain Res. 17:1993;41-52.
    • (1993) Mol. Brain Res. , vol.17 , pp. 41-52
    • Sola, C.1    Garcia-Ladona, F.J.2    Mengod, G.3    Probst, A.4    Frey, P.5    Palacios, J.M.6
  • 43
    • 0027198831 scopus 로고
    • Molecular cloning of the cDNA for a human amyloid precursor protein homolog: Evidence for a multigene family
    • Sprecher C.A., Grant F.J., Grimm G., O'Hara P.J., Norris F., Norris K., Foster D.C. Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family. Biochemistry. 32:1993;4481-4486.
    • (1993) Biochemistry , vol.32 , pp. 4481-4486
    • Sprecher, C.A.1    Grant, F.J.2    Grimm, G.3    O'Hara, P.J.4    Norris, F.5    Norris, K.6    Foster, D.C.7
  • 44
    • 0028577208 scopus 로고
    • Immunohistochemical evidence for apoptosis in Alzheimer's disease
    • Su J.H., Anderson A.J., Cummings B.J., Cotman C.W. Immunohistochemical evidence for apoptosis in Alzheimer's disease. NeuroReport. 5:1994;2529-2533.
    • (1994) NeuroReport , vol.5 , pp. 2529-2533
    • Su, J.H.1    Anderson, A.J.2    Cummings, B.J.3    Cotman, C.W.4
  • 45
    • 0029983170 scopus 로고    scopus 로고
    • Up-regulation of Bcl-2 is associated with neuronal DNA damage in Alzheimer's disease
    • Su J.H., Satou T., Anderson A.J., Cotman C.W. Up-regulation of Bcl-2 is associated with neuronal DNA damage in Alzheimer's disease. NeuroReport. 7:1996;437-440.
    • (1996) NeuroReport , vol.7 , pp. 437-440
    • Su, J.H.1    Satou, T.2    Anderson, A.J.3    Cotman, C.W.4
  • 46
    • 0030638139 scopus 로고    scopus 로고
    • Bax protein expression is increased in Alzheimer's brain: Correlations with DNA damage, Bcl-2 expression, and brain pathology
    • Su J.H., Deng G., Cotman C.W. Bax protein expression is increased in Alzheimer's brain: correlations with DNA damage, Bcl-2 expression, and brain pathology. J. Neuropathol. Exp. Neurol. 56:1997;86-93.
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 86-93
    • Su, J.H.1    Deng, G.2    Cotman, C.W.3
  • 47
    • 0030001220 scopus 로고    scopus 로고
    • Serum deprivation alters the expression and the splicing at exons 7, 8 and 15 of the β-amyloid precursor protein in the C6 glioma cell line
    • Sudoh S., Kawakami H., Nakamura S. Serum deprivation alters the expression and the splicing at exons 7, 8 and 15 of the β-amyloid precursor protein in the C6 glioma cell line. Mol. Brain Res. 39:1996;12-22.
    • (1996) Mol. Brain Res. , vol.39 , pp. 12-22
    • Sudoh, S.1    Kawakami, H.2    Nakamura, S.3
  • 48
    • 0028892186 scopus 로고
    • Amyloid β peptide induces cytoplasmic accumulation of amyloid protein precursor via tau protein kinase I/glycogen synthase kinase-3β in rat hippocampal neurons
    • Takashima A., Yamaguchi H., Noguchi K., Michel G., Ishiguro K., Sato K., Hoshino M., Hoshi M., Imahori K. Amyloid β peptide induces cytoplasmic accumulation of amyloid protein precursor via tau protein kinase I/glycogen synthase kinase-3β in rat hippocampal neurons. Neurosci. Lett. 198:1995;83-86.
    • (1995) Neurosci. Lett. , vol.198 , pp. 83-86
    • Takashima, A.1    Yamaguchi, H.2    Noguchi, K.3    Michel, G.4    Ishiguro, K.5    Sato, K.6    Hoshino, M.7    Hoshi, M.8    Imahori, K.9
  • 49
    • 0029060676 scopus 로고
    • Novel regulation of chondroitin sulfate glycosaminoglycan modification of amyloid precursor protein and its homologue APLP2
    • Thinakaran G., Slunt H.H., Sisodia S.S. Novel regulation of chondroitin sulfate glycosaminoglycan modification of amyloid precursor protein and its homologue APLP2. J. Biol. Chem. 270:1995;16522-16525.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16522-16525
    • Thinakaran, G.1    Slunt, H.H.2    Sisodia, S.S.3
  • 51
    • 0027985460 scopus 로고
    • A human amyloid precursor-like protein is highly homologous to a mouse sequence-specific DNA-binding protein
    • von der Kammer H., Hanes J., Klaidiny J., Heinzscheit K. A human amyloid precursor-like protein is highly homologous to a mouse sequence-specific DNA-binding protein. DNA Cell Biol. 13:1994;1137-1143.
    • (1994) DNA Cell Biol. , vol.13 , pp. 1137-1143
    • Von Der Kammer, H.1    Hanes, J.2    Klaidiny, J.3    Heinzscheit, K.4
  • 53
    • 0026442891 scopus 로고
    • Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid β protein precursor
    • Wasco W., Bupp K., Magendantz M., Gusella J.F., Tanzi R.E., Solomon F. Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid β protein precursor. Proc. Natl. Acad. Sci. U.S.A. 89:1992;10758-10762.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 10758-10762
    • Wasco, W.1    Bupp, K.2    Magendantz, M.3    Gusella, J.F.4    Tanzi, R.E.5    Solomon, F.6
  • 56
    • 0030042249 scopus 로고    scopus 로고
    • Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype
    • Yamatsuji T., Okamoto T., Takeda S., Murayama Y., Tanaka N., Nishimoto I. Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype. EMBO J. 15:1996;498-509.
    • (1996) EMBO J. , vol.15 , pp. 498-509
    • Yamatsuji, T.1    Okamoto, T.2    Takeda, S.3    Murayama, Y.4    Tanaka, N.5    Nishimoto, I.6
  • 57
    • 0025219026 scopus 로고
    • Genomic organization of the human amyloid beta-protein precursor gene
    • Yoshikai S., Sasaki H., Doh-ura K., Furuya H., Sakaki Y. Genomic organization of the human amyloid beta-protein precursor gene. Gene. 87:1990;257-263.
    • (1990) Gene , vol.87 , pp. 257-263
    • Yoshikai, S.1    Sasaki, H.2    Doh-Ura, K.3    Furuya, H.4    Sakaki, Y.5


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