메뉴 건너뛰기




Volumn 2, Issue 1, 2001, Pages 20-24

Linkage analysis of the 5q31-33 candidate region for asthma in 240 UK families

Author keywords

Asthma; Atopy; Chromosome 5q; IgE; Linkage

Indexed keywords

ARTICLE; ASTHMA; CHROMOSOME 5; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETICS; HUMAN; PHENOTYPE; UNITED KINGDOM;

EID: 0035259186     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6363723     Document Type: Article
Times cited : (21)

References (36)
  • 2
    • 14444281570 scopus 로고    scopus 로고
    • Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region
    • Frazer KA, Ueda Y, Zhu Y et al. Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region. Genome Res 1997; 7: 495-512.
    • (1997) Genome Res , vol.7 , pp. 495-512
    • Frazer, K.A.1    Ueda, Y.2    Zhu, Y.3
  • 4
    • 0032589460 scopus 로고    scopus 로고
    • Beta2-adrenergic receptor polymorphisms affect airway responsiveness to salbutamol in asthmatics
    • Kotani Y, Nishimura Y, Maeda H, Yokoyama M. Beta2-adrenergic receptor polymorphisms affect airway responsiveness to salbutamol in asthmatics. J Asthma 1999; 36: 583-590.
    • (1999) J Asthma , vol.36 , pp. 583-590
    • Kotani, Y.1    Nishimura, Y.2    Maeda, H.3    Yokoyama, M.4
  • 5
    • 0032909902 scopus 로고    scopus 로고
    • Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients
    • Lipworth BJ, Hall IP, Tan S, Aziz I, Coutie W. Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients. Chest 1999; 115: 324-328.
    • (1999) Chest , vol.115 , pp. 324-328
    • Lipworth, B.J.1    Hall, I.P.2    Tan, S.3    Aziz, I.4    Coutie, W.5
  • 7
    • 0028472787 scopus 로고
    • Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma
    • Lane SJ, Arm JP, Staynov DZ, Lee TH. Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma. Am J Respir Cell Mol Biol 1994; 11: 42-18.
    • (1994) Am J Respir Cell Mol Biol , vol.11 , pp. 42-118
    • Lane, S.J.1    Arm, J.P.2    Staynov, D.Z.3    Lee, T.H.4
  • 8
    • 0031590522 scopus 로고    scopus 로고
    • Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma
    • Sanak M, Simon HU, Szczeklik A. Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma. Lancet 1997; 350: 1599-1600.
    • (1997) Lancet , vol.350 , pp. 1599-1600
    • Sanak, M.1    Simon, H.U.2    Szczeklik, A.3
  • 9
    • 0028230946 scopus 로고
    • Linkage analysis of IL4 and other chromosome 5q31.1 total serum immunoglobulin E concentrations
    • Marsh DG, Neely JD, Breazeale DR et al. Linkage analysis of IL4 and other chromosome 5q31.1 total serum immunoglobulin E concentrations. Science 1994; 264: 1152-1156.
    • (1994) Science , vol.264 , pp. 1152-1156
    • Marsh, D.G.1    Neely, J.D.2    Breazeale, D.R.3
  • 12
    • 9844247994 scopus 로고    scopus 로고
    • Genetic control of serum IgE levels and asthma: Linkage and linkage disequilibrium studies in an isolated population
    • Laitinen T, Kauppi P, Ignatius J et al. Genetic control of serum IgE levels and asthma: linkage and linkage disequilibrium studies in an isolated population. Hum Molec Genet 1997; 6: 2069-2076.
    • (1997) Hum Molec Genet , vol.6 , pp. 2069-2076
    • Laitinen, T.1    Kauppi, P.2    Ignatius, J.3
  • 13
    • 0029152197 scopus 로고
    • Genetic susceptibility to asthma - Bronchial, hyperresponsiveness coinherited with a major gene for atopy
    • Postma DS, Bleecker ER, Amelung PJ et al. Genetic susceptibility to asthma - bronchial, hyperresponsiveness coinherited with a major gene for atopy. N Engl J Med 1995; 333: 894-900.
    • (1995) N Engl J Med , vol.333 , pp. 894-900
    • Postma, D.S.1    Bleecker, E.R.2    Amelung, P.J.3
  • 14
    • 0032417095 scopus 로고    scopus 로고
    • Linkage of chromosome 5q and 11q gene markers to asthma-associated quantitative traits in Australian children
    • Palmer LJ, Daniels SE, Rye PJ et al. Linkage of chromosome 5q and 11q gene markers to asthma-associated quantitative traits in Australian children. Am J Respir Crit Care Med 1998; 158: 1825-1830.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 1825-1830
    • Palmer, L.J.1    Daniels, S.E.2    Rye, P.J.3
  • 15
    • 0030610185 scopus 로고    scopus 로고
    • 2-adrenoceptor polymorphism is associated with elevated IgE levels in asthmatic families
    • 2-adrenoceptor polymorphism is associated with elevated IgE levels in asthmatic families. J. Allergy Clin Immunol 1997; 100: 261-265.
    • (1997) J. Allergy Clin Immunol , vol.100 , pp. 261-265
    • Dewar, J.C.1    Wilkinson, J.2    Wheatley, A.3
  • 16
    • 0029968806 scopus 로고    scopus 로고
    • Allelic association of gene markers on chromosomes 5q and 11q with atopy and bronchial hyperresponsiveness
    • Doull IJM, Lawrence S, Watson M et al. Allelic association of gene markers on chromosomes 5q and 11q with atopy and bronchial hyperresponsiveness. Am J Resp Crit Care Med 1996; 153: 1280-1284.
    • (1996) Am J Resp Crit Care Med , vol.153 , pp. 1280-1284
    • Doull, I.J.M.1    Lawrence, S.2    Watson, M.3
  • 17
    • 0029056632 scopus 로고
    • Evidence for two unlinked loci regulating total serum IgE levels
    • Xu J, Levitt RC, Panhuysen C et al. Evidence for two unlinked loci regulating total serum IgE levels. Am J Hum Genet 1995; 57: 425-430.
    • (1995) Am J Hum Genet , vol.57 , pp. 425-430
    • Xu, J.1    Levitt, R.C.2    Panhuysen, C.3
  • 18
    • 0030656507 scopus 로고    scopus 로고
    • Evidence for linkage between asthma/atopy in childhood and chromosome 5q31-q33 in a Japanese population
    • Noguchi E, Shibasaki M, Arinami T et al. Evidence for linkage between asthma/atopy in childhood and chromosome 5q31-q33 in a Japanese population. Am J Resp Crit Care Med 1997; 156: 1390-1393.
    • (1997) Am J Resp Crit Care Med , vol.156 , pp. 1390-1393
    • Noguchi, E.1    Shibasaki, M.2    Arinami, T.3
  • 19
    • 0030903861 scopus 로고    scopus 로고
    • A genome-wide search for asthma susceptibility loci in ethnically diverse populations
    • Marsh DG, Ma'estri NE, Freidhoff LR et al. A genome-wide search for asthma susceptibility loci in ethnically diverse populations. Nat Genet 1997; 15: 389-392.
    • (1997) Nat Genet , vol.15 , pp. 389-392
    • Marsh, D.G.1    Ma'estri, N.E.2    Freidhoff, L.R.3
  • 20
    • 0031690669 scopus 로고    scopus 로고
    • Genetic regulation of Dermatophagoides pteronyssinus-specific IgE responsiveness: A genome-wide multipoint linkage analysis in families recruited through 2 asthmatic sibs
    • Hizawa N, Freidhoff LR, Chiu YF et al. Genetic regulation of Dermatophagoides pteronyssinus-specific IgE responsiveness: a genome-wide multipoint linkage analysis in families recruited through 2 asthmatic sibs. J Allergy Clin Immunol 1998; 102: 436-442.
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 436-442
    • Hizawa, N.1    Freidhoff, L.R.2    Chiu, Y.F.3
  • 21
    • 16044372682 scopus 로고    scopus 로고
    • A genome-wide search for quantitative trait loci underlying asthma
    • Daniels SE, Bhattacharrya S, James A et al. A genome-wide search for quantitative trait loci underlying asthma. Nature 1996; 383: 247-250.
    • (1996) Nature , vol.383 , pp. 247-250
    • Daniels, S.E.1    Bhattacharrya, S.2    James, A.3
  • 22
    • 0033563231 scopus 로고    scopus 로고
    • A genome-wide search for linkage to asthma
    • German Asthma Genetics Group
    • Wjst M, Fischer G, Immervoll T et al. A genome-wide search for linkage to asthma. German Asthma Genetics Group. Genomics 1999; 58: 1-8.
    • (1999) Genomics , vol.58 , pp. 1-8
    • Wjst, M.1    Fischer, G.2    Immervoll, T.3
  • 23
    • 0029766848 scopus 로고    scopus 로고
    • Absence of linkage between 5q markers and serum IgE levels in four large atopic families
    • Blumenthal MN, Wang Z, Weber JL, Rich SS. Absence of linkage between 5q markers and serum IgE levels in four large atopic families. Clin Exp Allergy 1996; 26: 892-896.
    • (1996) Clin Exp Allergy , vol.26 , pp. 892-896
    • Blumenthal, M.N.1    Wang, Z.2    Weber, J.L.3    Rich, S.S.4
  • 24
    • 0030804127 scopus 로고    scopus 로고
    • Absence of genetic linkage of chromosome 5q31 with asthma and atopy in the general population
    • Kamitani A, Wong ZYH, Dickson P et al. Absence of genetic linkage of chromosome 5q31 with asthma and atopy in the general population. Thorax 1997; 52: 816-817.
    • (1997) Thorax , vol.52 , pp. 816-817
    • Kamitani, A.1    Wong, Z.Y.H.2    Dickson, P.3
  • 25
    • 0032873530 scopus 로고    scopus 로고
    • Dense mapping of chromosome 12q13.12-q23.3 and linkage to asthma and atopy
    • Barnes KC, Freidhoff LR, Nickel R et al. Dense mapping of chromosome 12q13.12-q23.3 and linkage to asthma and atopy. J Allergy Clin Immunol 1999; 104: 485-491.
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 485-491
    • Barnes, K.C.1    Freidhoff, L.R.2    Nickel, R.3
  • 26
    • 0030272144 scopus 로고    scopus 로고
    • Linkage of asthma and total serum IgE concentration to markers on chromosome 12q -evidence from Afro-Caribbean and Caucasian populations
    • Barnes KC, Neely JD, Duffy DL et al. Linkage of asthma and total serum IgE concentration to markers on chromosome 12q -evidence from Afro-Caribbean and Caucasian populations. Genomics 1996; 37: 41-50.
    • (1996) Genomics , vol.37 , pp. 41-50
    • Barnes, K.C.1    Neely, J.D.2    Duffy, D.L.3
  • 27
    • 0032213693 scopus 로고    scopus 로고
    • Linkage of asthma to markers on chromosome 12 in a sample of 240 families using quantitative phenotype scores
    • Wilkinson J., Grimley S, Collins A, Thomas NS, Holgate ST, Morton N. Linkage of asthma to markers on chromosome 12 in a sample of 240 families using quantitative phenotype scores. Genomics 1998; 53: 251-259.
    • (1998) Genomics , vol.53 , pp. 251-259
    • Wilkinson, J.1    Grimley, S.2    Collins, A.3    Thomas, N.S.4    Holgate, S.T.5    Morton, N.6
  • 29
    • 12944286556 scopus 로고    scopus 로고
    • A first trial of retrospective collaboration for positional cloning in complex inheritance: Assay of the cytokine region on chromosome 5 by the Consortium on Asthma Genetics (COAG)
    • Lonjou C, Barnes K, Chen H et al. A first trial of retrospective collaboration for positional cloning in complex inheritance: assay of the cytokine region on chromosome 5 by the Consortium on Asthma Genetics (COAG). Proc Natl Acad Sci USA 2000; 97: 10942-10947.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10942-10947
    • Lonjou, C.1    Barnes, K.2    Chen, H.3
  • 30
    • 0028072730 scopus 로고
    • Genetic analysis of atopy and asthma as quantitative traits and ordered polychotomies
    • Lawrence S, Beasley R, Doull I et al. Genetic analysis of atopy and asthma as quantitative traits and ordered polychotomies. Annals Hum Genet 1994; 58: 359-368.
    • (1994) Annals Hum Genet , vol.58 , pp. 359-368
    • Lawrence, S.1    Beasley, R.2    Doull, I.3
  • 31
    • 0024853139 scopus 로고
    • Validity and repeat-ability of the IUATLD (1984) Bronchial Symptoms Questionnaire: An international comparison
    • Burney PG, Laitinen LA, Perdrizet S et al. Validity and repeat-ability of the IUATLD (1984) Bronchial Symptoms Questionnaire: an international comparison. Eur Resp J 1989; 2: 940-945.
    • (1989) Eur Resp J , vol.2 , pp. 940-945
    • Burney, P.G.1    Laitinen, L.A.2    Perdrizet, S.3
  • 32
    • 0027138282 scopus 로고
    • Self-reported prevalence of asthma symptoms in children in Australia, England, Germany and New Zealand: An international comparison using the ISAAC protocol
    • Pearce N, Weiland S, Keil U et al. Self-reported prevalence of asthma symptoms in children in Australia, England, Germany and New Zealand: an international comparison using the ISAAC protocol. Eur Resp J 1993; 6: 1455-1461.
    • (1993) Eur Resp J , vol.6 , pp. 1455-1461
    • Pearce, N.1    Weiland, S.2    Keil, U.3
  • 33
    • 0020604491 scopus 로고
    • Rapid method for measurement of bronchial responsiveness
    • Yan K, Salome C, Woolcock AJ. Rapid method for measurement of bronchial responsiveness. Thorax 1983; 38: 760-765.
    • (1983) Thorax , vol.38 , pp. 760-765
    • Yan, K.1    Salome, C.2    Woolcock, A.J.3
  • 34
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16: 1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 36
    • 0029866674 scopus 로고    scopus 로고
    • Logarithm of odds (lods) for linkage in complex inheritance
    • Morton NE. Logarithm of odds (lods) for linkage in complex inheritance. Proc Natl Acad Sci USA 1996; 93: 3471-3476.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3471-3476
    • Morton, N.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.