Distribution of recombinant adenovirus in the cerebrospinal fluid of nonhuman primates

Human Gene Therapy

Volumn 10, Issue 14, 1999, Pages 2347-2354

  Driesse, M J ^a   Kros, J M ^a   Avezaat, C J J ^a   Valerio, D ^b,c   Vecht, C J ^a   Bout, A ^c   Sillevis Smitt, P A E ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c CRUCELL HOLLAND BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIBODY; VIRUS VECTOR;

ADENOVIRUS; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CEREBROSPINAL FLUID; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSDUCTION; IMMUNE RESPONSE; IMMUNOMODULATION; MACACA; NONHUMAN; RAT;

ADENOVIRIDAE; ANIMALS; ANTIBODY FORMATION; BETA-GALACTOSIDASE; GENETIC VECTORS; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENOUS; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SPINAL; MACACA MULATTA; RATS; RATS, INBRED F344;

ADENOVIRIDAE; ANIMALIA; ARACHNOIDEA; MACACA; PRIMATES;

EID: 0033588921     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349950016997     Document Type: Article

References (33)

1. BAJOCCHI, G., FELDMAN, S.H., CRYSTAL, R.G., and MASTRANGELI, A. (1993). Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors. Nature Genet. 3, 229-234.
2. BETZ, A.L., YANG, G.-Y., and DAVIDSON, B.L. (1995). Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain. J. Cereb. Blood Flow Metab. 15, 547-551.
3. BLANEY, S.M., POPLACK, D.G., GODWIN, K., et al. (1995). Effect of body position on ventricular CSF methotrexate concentration following intralumbar administration. J. Clin. Oncol. 13, 177-179.
4. BOUT, A., VALERIO, D., and SCHOLTE, B.J. (1993). In vivo transfer and expression of the lacZ gene in the mouse lung. Exp. Lung Res. 19, 193-202.
5. BOUT, A., IMLER, J.-L., SCHULTZ, H., et al. (1994a). In vivo adenovirus-mediated transfer of human CFTR cDNA to rhesus monkey airway epithelium: Efficacy, toxicity and safety. Gene Ther. 1, 385-394.
6. BOUT, A., PERRICAUDET, M., BASKIN, G., IMLER, J.-L., SCHOLTE, B.J., PAVIRANI, A., and VALERIO, D. (1994). Lung gene therapy: In vivo adenovirus-mediated gene transfer to rhesus monkey airway epithelium. Hum. Gene Ther. 5, 3-10.
7. BRADBURY, M.W.B. (1990). Overview of passage routes of interstitial fluid to the lymphatics: History and current concepts. In Pathophysiology of the Blood-Brain Barrier. (Elsevier, Amsterdam-New York-Oxford) pp. 403-412.
8. CSERR, H.F., and KNOPF, P.M. (1992). Cervical lymphatics, the blood-brain barrier and immunoreactivity of the brain: A new view. Immunol. Today 13, 507-512.
9. CSERR, H.F., DEPASQUALE, M., HARLING-BERG, C.J., et al. (1992). Afferent and efferent arms of the humoral immune response to CSF-administered albumins in a rat model with normal blood-brain barrier permeability. J. Neuroimmunol. 41, 195-202.
10. DE JONG, J.C., BIJLSMA, K., WERMENBOL, A.G., et al. (1993). Detection, typing and subtyping of enteric adenoviruses 40 and 41 from fecal samples and observation of changing incidences of infections with these types and subtypes. J. Clin. Microbiol. 31, 1562-1569.
11. ERLICH, S.S., MCCOMB, J.G., et al. (1986). Ultrastructural morphology of the olfactory pathway for cerebrospinal fluid drainage in the rabbit. J. Neurosurg. 64, 466-473.
12. FABRY, Z., RAINE, C.S., and HART, M.N. (1994). Nervous tissue as an immune compartment: The dialect of the immune response in the CNS. Immunol. Today 15, 218-224.
13. FALLAUX, F.J., KRANENBURG, O., CRAMER, S.J., et al. (1996). Characterization of 911: A new helper cell-line for the titration and propagation of early region-1 deleted adenoviral vectors. Hum. Gene Ther. 7, 215-222.
14. FISHMAN, R.A. (1992). Cerebrospinal Fluid in Diseases of the Nervous System. (W.B. Saunders, Philadelphia).
15. FORTUNATI, E., BOUT, A., ZANTA, M.A., et al. (1996). In vitro and in vivo gene transfer to pulmonary cells mediated by cationic liposomes. Biochim. Biophys. Acta. 1306, 55-62.
16. FURLAN, R., POLIANI, P.L., GALBIATI, F., et al. (1998). Central nervous system delivery of interleukin 4 by a nonreplicative herpes simplex type 1 viral vector ameliorates autoimmune demyelination. Hum. Gene Ther. 9, 2605-2617.
17. GORDON, L.B., KNOPF, P.M., and CSERR, H.F. (1992). Ovalbumin is more immunogenic when introduced into brain or cerebrospinal fluid than into extracerebral sites. J. Neuroimmunol. 40, 81-88.
18. GRAVEL, C., GOETZ, R., et al. (1997). Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons. Nature Med. 3, 765-770.
19. KOCHANEK, S., CLEMENS, P.R., MITANI, K., et al. (1996). A new adenoviral vector: Replacement of all viral coding sequences with 28kb of DNA independently expressing both full-length dystrophin and β-galactosidase. Proc. Natl. Acad. Sci. U.S.A. 93, 5731-5736.
20. LE GAL LA SALLE, G., ROBERT, J.J., BERARD, S., et al. (1993). An adenovirus vector for gene transfer into neurons and glia in the brain. Science 259, 988-990.
21. MCCOMB, J.G., and HYMAN, S. (1990). Lymphatic drainage of cerebrospinal fluid in the primate. In Pathophysiology of the Blood-Brain Barrier. (Elsevier, Amsterdam-New York-Oxford) pp. 421-438.
22. MCCULLY, C.L., BALIS, F.M., BACHER, J., et al. (1990). A rhesus monkey model for continuous infusion of drugs into cerebrospinal fluid. Lab. Anim. Sci. 40, 520-525.
23. MILHORAT, T.H., and CLARK, R.G. (1970). Some observations on the circulation of phenosulfonphthalein in cerebrospinal fluid: Normal flow and the flow in hydrocephalus. J. Neurosurg. 32, 522-228.
24. MORRAL, N., O'NEAL, W., ZHOU, H., et al. (1997). Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: comparison of E2a wild type and E2a deleted vectors. Hum. Gene Ther. 8, 1275-1286.
25. OHASHI, T., KAZUHIKO, W., UEHARA, K., et al. (1996). Adenovirus-mediated gene transfer and expression of human β-glucuronidase gene in the liver, spleen, and central nervous system in mucopolysaccharidosis type VII mice. Proc. Natl. Acad. Sci. U.S.A. 94, 1287-1292.
26. POSNER, J.B. (1995). Leptomeningeal metastases. In Neurologic Complications of Cancer. (F.A. Davis, Philadelphia) pp. 143-171.
27. PRECIOUS, B., and RUSSEL, W. (1985). Growth, purification and titration of adenoviruses. In Virology: A Practical Approach. (Raven Press, New York) pp. 157-167.
28. SHAPIRO, W.R., YOUNG, D.F., and MEHTA, B.M. (1975). Methotrexate: Distribution in cerebrospinal fluid after intravenous, ventricular and lumbar injections. N. Engl. J. Med. 293, 161-166.
29. SMITH, J.G., and ECK, S.L. (1998). Immune response to viral vectors. In Gene Therapy for Neurological Disorders and Brain Tumors. (Humana Press, Totowa, NJ) pp. 147-157.
30. SNIDER, R., and LEE, J. (1961). A Stereotactic Atlas of the Monkey Brain (Macaca mulatta). (University of Chicago Press, Chicago and London).
31. STEVENSON, P.C., HAWKE, S., SLOAN, D.J., and BANGHAM, R.M. (1997). The immunogenicity of intracerebral virus infection depends on anatomical site. J. Virol. 71, 145-151.
32. VINCENT, A.J.P.E., ESANDI, M.C., VAN SOMEREN, G., et al. (1996). Treatment of leptomeningeal metastases in a rat model using a recombinant adenovirus containing the HSV-tk gene. J. Neurosurg. 85, 648-654.
33. VINCENT, A.J.P.E., ESANDI, M.C., AVEZAAT, C.J.J., et al. (1997). Preclinical testing of recombinant adenoviral HSV-tk gene therapy for CNS malignancies. Neurosurgery 41, 442-451.