메뉴 건너뛰기




Volumn 42, Issue , 2001, Pages 439-457

26 Optimum study designs

Author keywords

[No Author keywords available]

Indexed keywords

CASE CONTROL STUDY; CHROMOSOME MAP; COST BENEFIT ANALYSIS; DEMOGRAPHY; ECONOMICS; GENETIC LINKAGE; GENOTYPE; HUMAN; META ANALYSIS; METHODOLOGY; PHENOTYPE; REVIEW; SAMPLE SIZE;

EID: 0035234160     PISSN: 00652660     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0065-2660(01)42035-9     Document Type: Review
Times cited : (14)

References (46)
  • 1
    • 0028058128 scopus 로고
    • Robust variance-components approach for assessing genetic linkage in pedigrees
    • C.I. Amos Robust variance-components approach for assessing genetic linkage in pedigrees Am. J. Hum. Genet. 54 1994 535 543
    • (1994) Am. J. Hum. Genet. , vol.54 , pp. 535-543
    • Amos, C.I.1
  • 2
    • 0003958977 scopus 로고    scopus 로고
    • SOLAR: Sequential oligogenic linkage analysis routines
    • J. Blangero L. Almasy SOLAR: Sequential oligogenic linkage analysis routines Technical notes 1996 Southwest Foundation for Biomedical Research, Population Genetics Laboratory San Antonio, TX
    • (1996)
    • Blangero, J.1    Almasy, L.2
  • 3
    • 0030881661 scopus 로고    scopus 로고
    • Accurate inference of relationships in sib-pair linkage studies
    • M. Boehnke N.J. Cox Accurate inference of relationships in sib-pair linkage studies Am. J. Hum. Genet. 61 2 1996 423 429
    • (1996) Am. J. Hum. Genet. , vol.61 , Issue.2 , pp. 423-429
    • Boehnke, M.1    Cox, N.J.2
  • 4
    • 0033592988 scopus 로고    scopus 로고
    • Genetic epidemiology of single-nucleotide polymorphisms
    • A. Collins C. Lonjou N.E. Morton Genetic epidemiology of single-nucleotide polymorphisms Proc. Natl. Acad. Sci. USA 96 1999 15173 15177 (26)
    • (1999) , pp. 15173-15177
    • Collins, A.1    Lonjou, C.2    Morton, N.E.3
  • 5
    • 0030480587 scopus 로고    scopus 로고
    • Two-stage global search designs for linkage analysis using pairs of affected relatives
    • R.C. Elston X. Guo L.V. Williams Two-stage global search designs for linkage analysis using pairs of affected relatives Genet. Epidemiol. 13 6 1996 535 558
    • (1996) Genet. Epidemiol. , vol.13 , Issue.6 , pp. 535-558
    • Elston, R.C.1    Guo, X.2    Williams, L.V.3
  • 6
    • 0029075560 scopus 로고
    • The transmission/disequilibrium test: History, subdivision, and admixture
    • W.J. Ewens R.S. Spielman The transmission/disequilibrium test: History, subdivision, and admixture Am. J. Hum. Genet. 57 2 1995 455 464
    • (1995) Am. J. Hum. Genet. , vol.57 , Issue.2 , pp. 455-464
    • Ewens, W.J.1    Spielman, R.S.2
  • 7
    • 0023235253 scopus 로고
    • Haplotype relative risks: An easy reliable way to construct a proper control sample for risk calculations
    • C.T. Falk P. Rubinstein Haplotype relative risks: An easy reliable way to construct a proper control sample for risk calculations Ann. Hum. Genet. 51 1987 227 233
    • (1987) Ann. Hum. Genet. , vol.51 , pp. 227-233
    • Falk, C.T.1    Rubinstein, P.2
  • 8
    • 0033366671 scopus 로고    scopus 로고
    • Combined linkage and association sib-pair analysis for quantitative traits
    • D.W. Fulker S.S. Cherny P.C. Sham J.K. Hewitt Combined linkage and association sib-pair analysis for quantitative traits Am. J. Hum. Genet. 64 1999 259 267
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 259-267
    • Fulker, D.W.1    Cherny, S.S.2    Sham, P.C.3    Hewitt, J.K.4
  • 9
    • 0030927756 scopus 로고    scopus 로고
    • Relationship estimation in affected sib pair analysis of late-onset diseases
    • H.H. Göring J. Ott Relationship estimation in affected sib pair analysis of late-onset diseases Eur. J. Hum. Genet. 5 2 1997 60 77
    • (1997) Eur. J. Hum. Genet. , vol.5 , Issue.2 , pp. 60-77
    • Göring, H.H.1    Ott, J.2
  • 10
    • 0030843362 scopus 로고    scopus 로고
    • A linkage strategy for detection of human quantitative-trait loci. I. Generalized relative risk ratios and power of sibpairs with extreme trait values
    • C. Gu D.C. Rao A linkage strategy for detection of human quantitative-trait loci. I. Generalized relative risk ratios and power of sibpairs with extreme trait values Am. J. Hum. Genet. 61 1997 200 210
    • (1997) Am. J. Hum. Genet. , vol.61 , pp. 200-210
    • Gu, C.1    Rao, D.C.2
  • 11
    • 0030873885 scopus 로고    scopus 로고
    • A linkage strategy for detection of human quantitative-trait loci. II. Optimization of study designs based on extreme sibpairs and generalized relative risk ratios
    • C. Gu D.C. Rao A linkage strategy for detection of human quantitative-trait loci. II. Optimization of study designs based on extreme sibpairs and generalized relative risk ratios Am. J. Hum. Genet. 61 1997 211 222
    • (1997) Am. J. Hum. Genet. , vol.61 , pp. 211-222
    • Gu, C.1    Rao, D.C.2
  • 12
    • 0029565579 scopus 로고
    • A chromosome-based method to infer IBD scores for missing and ambiguous markers
    • C. Gu B.K. Suarez T. Reich A.A. Todorov A chromosome-based method to infer IBD scores for missing and ambiguous markers Genet. Epidemiol. 12 1995 871 876
    • (1995) Genet. Epidemiol. , vol.12 , pp. 871-876
    • Gu, C.1    Suarez, B.K.2    Reich, T.3    Todorov, A.A.4
  • 13
    • 0030471517 scopus 로고    scopus 로고
    • Combining extremely concordant sibpairs with extremely discordant sibpairs provides a cost effective way to linkage analysis of QTL
    • C. Gu A.A. Todorov D.C. Rao Combining extremely concordant sibpairs with extremely discordant sibpairs provides a cost effective way to linkage analysis of QTL Genet. Epidemiol. 13 1996 513 533
    • (1996) Genet. Epidemiol. , vol.13 , pp. 513-533
    • Gu, C.1    Todorov, A.A.2    Rao, D.C.3
  • 14
    • 85120112863 scopus 로고    scopus 로고
    • The affected-pedigree-member method revisited under population stratification
    • C. Gu M.A. Miller T. Reich D.C. Rao The affected-pedigree-member method revisited under population stratification Statistical Methods in Genetics: The IMA Volumes in Mathematics and Its Applications Vol. 112 1998 Springer-Verlag New York 165 180
    • (1998) , pp. 165-180
    • Gu, C.1    Miller, M.A.2    Reich, T.3    Rao, D.C.4
  • 15
    • 0031738023 scopus 로고    scopus 로고
    • Meta-analysis methodology for combining non-parametric sibpair linkage results: Genetic homogeneity and identical markers
    • C. Gu M. Province A. Todorov D.C. Rao Meta-analysis methodology for combining non-parametric sibpair linkage results: Genetic homogeneity and identical markers Genet. Epidemiol. 15 1998 609 626
    • (1998) Genet. Epidemiol. , vol.15 , pp. 609-626
    • Gu, C.1    Province, M.2    Todorov, A.3    Rao, D.C.4
  • 16
    • 0032980338 scopus 로고    scopus 로고
    • An Icelandic saga on a centralized healthcare database and democratic decision making
    • J. Gulcher K. Stefansson An Icelandic saga on a centralized healthcare database and democratic decision making Nat. Biotechnol. 17 7 1999 620
    • (1999) Nat. Biotechnol. , vol.17 , Issue.7 , pp. 620
    • Gulcher, J.1    Stefansson, K.2
  • 18
    • 0344500841 scopus 로고    scopus 로고
    • A scan for linkage disequilibrium across the human genome
    • G.A. Huttley M.W. Smith M. Carrington S.J. O'Brien A scan for linkage disequilibrium across the human genome Genetics 152 1999 1711 1722
    • (1999) Genetics , vol.152 , pp. 1711-1722
    • Huttley, G.A.1    Smith, M.W.2    Carrington, M.3    O'Brien, S.J.4
  • 19
    • 0015091972 scopus 로고
    • Frequency in relatives for an all-or-not trait
    • J.W. James Frequency in relatives for an all-or-not trait Ann. Hum. Genet. 35 1971 47 49
    • (1971) Ann. Hum. Genet. , vol.35 , pp. 47-49
    • James, J.W.1
  • 20
    • 0028894185 scopus 로고
    • Linkage disequilibrium as a gene-mapping tool
    • L.B. Jorde Linkage disequilibrium as a gene-mapping tool Am. J. Hum. Genet. 56 1995 11 14
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 11-14
    • Jorde, L.B.1
  • 21
    • 0033039497 scopus 로고    scopus 로고
    • Prospects for whole-genome linkage disequilibrium mapping of common disease genes
    • L. Kruglyak Prospects for whole-genome linkage disequilibrium mapping of common disease genes Nat. Genet. 22 2 1999 139 144
    • (1999) Nat. Genet. , vol.22 , Issue.2 , pp. 139-144
    • Kruglyak, L.1
  • 22
    • 0029046177 scopus 로고
    • Complete multipoint sib-pair analysis of qualitative and quantitative traits
    • L. Kruglyak E. Lander Complete multipoint sib-pair analysis of qualitative and quantitative traits Am. J. Hum. Genet. 57 1995 439 454
    • (1995) Am. J. Hum. Genet. , vol.57 , pp. 439-454
    • Kruglyak, L.1    Lander, E.2
  • 23
    • 0000803318 scopus 로고
    • Construction of multilocus genetic linkage maps in humans
    • E. Lander P. Green Construction of multilocus genetic linkage maps in humans Proc. Natl. Acad. Sci. USA 84 1987 2363 2367
    • (1987) , pp. 2363-2367
    • Lander, E.1    Green, P.2
  • 24
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • E. Lander L. Kruglyak Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results Nat. Genet. 11 1995 241 247
    • (1995) Nat. Genet. , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 25
    • 0032231748 scopus 로고    scopus 로고
    • Mapping genes that underlie ethnic differences in disease risk: Methods for detecting linkage in admixed populations, by conditioning on parental admixture
    • P.M. McKeigue Mapping genes that underlie ethnic differences in disease risk: Methods for detecting linkage in admixed populations, by conditioning on parental admixture Am. J. Hum. Genet. 63 1998 241 251
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 241-251
    • McKeigue, P.M.1
  • 26
    • 0032530165 scopus 로고    scopus 로고
    • Tests and estimates of allelic association in complex inheritance
    • N.E. Morton A. Collins Tests and estimates of allelic association in complex inheritance Proc. Natl. Acad. Sci. USA 95 1998 11389 11393 (19)
    • (1998) , pp. 11389-11393
    • Morton, N.E.1    Collins, A.2
  • 27
    • 0024536523 scopus 로고
    • Statistical properties of the haplotype relative risk
    • J. Ott Statistical properties of the haplotype relative risk Genet. Epidemiol. 6 1989 127 130
    • (1989) Genet. Epidemiol. , vol.6 , pp. 127-130
    • Ott, J.1
  • 28
    • 0033992497 scopus 로고    scopus 로고
    • Positional cloning of disease genes: Advantages of genetic isolates
    • L. Peltonen Positional cloning of disease genes: Advantages of genetic isolates Hum. Hered. 50 1 1999 66 75
    • (1999) Hum. Hered. , vol.50 , Issue.1 , pp. 66-75
    • Peltonen, L.1
  • 29
    • 0033358548 scopus 로고    scopus 로고
    • Use of unlinked genetic markers to detect population stratification in association studies
    • J.K. Pritchard N.A. Rosenberg Use of unlinked genetic markers to detect population stratification in association studies Am. J. Hum. Genet. 65 1999 220 228
    • (1999) Am. J. Hum. Genet. , vol.65 , pp. 220-228
    • Pritchard, J.K.1    Rosenberg, N.A.2
  • 30
    • 85007201620 scopus 로고    scopus 로고
    • A multivariate and multilocus variance components approach using structural relationships to assess quantitative trait linkage via SEGPATH
    • M.A. Province T. Rice I.B. Borecki C. Gu D.C. Rao A multivariate and multilocus variance components approach using structural relationships to assess quantitative trait linkage via SEGPATH Genet. Epidemiol. 2000 (in press)
    • (2000) Genet. Epidemiol.
    • Province, M.A.1    Rice, T.2    Borecki, I.B.3    Gu, C.4    Rao, D.C.5
  • 31
    • 0031907395 scopus 로고    scopus 로고
    • CAT scans, PET scans, and genomic scans
    • D.C. Rao CAT scans, PET scans, and genomic scans Genet. Epidemiol. 15 1998 1 18
    • (1998) Genet. Epidemiol. , vol.15 , pp. 1-18
    • Rao, D.C.1
  • 32
    • 85120124902 scopus 로고    scopus 로고
    • Principles and methods in the study of complex phenotypes
    • D.C. Rao C. Gu Principles and methods in the study of complex phenotypes J. Benjamin R. Ebstein R.H. Belmaker Molecular Genetics and Human Personality 2000 American Psychiatric Press Washington, DC
    • (2000)
    • Rao, D.C.1    Gu, C.2
  • 33
    • 0025019555 scopus 로고
    • Linkage strategies for genetically complex traits. I. Multilocus models
    • N. Risch Linkage strategies for genetically complex traits. I. Multilocus models Am. J. Hum. Genet. 46 1990 222 228
    • (1990) Am. J. Hum. Genet. , vol.46 , pp. 222-228
    • Risch, N.1
  • 34
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • N. Risch K. Merikangas The future of genetic studies of complex human diseases Science 273 1996 1516 1517
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 35
    • 0032427048 scopus 로고    scopus 로고
    • The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human disease I. DNA pooling
    • N. Risch J. Teng The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human disease I. DNA pooling Genome Res. 8 12 1998 1273 1288
    • (1998) Genome Res. , vol.8 , Issue.12 , pp. 1273-1288
    • Risch, N.1    Teng, J.2
  • 36
    • 0029001682 scopus 로고
    • Extreme discordant sib pairs for mapping quantitative trait loci in humans
    • N. Risch H. Zhang Extreme discordant sib pairs for mapping quantitative trait loci in humans Science 268 1995 1584 1589
    • (1995) Science , vol.268 , pp. 1584-1589
    • Risch, N.1    Zhang, H.2
  • 37
    • 0027377799 scopus 로고
    • Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM
    • R.S. Spielman R.E. McGinnis W.J. Ewens Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM Am. J. Hum. Genet. 52 1993 506 516
    • (1993) Am. J. Hum. Genet. , vol.52 , pp. 506-516
    • Spielman, R.S.1    McGinnis, R.E.2    Ewens, W.J.3
  • 38
    • 0018150112 scopus 로고
    • The generalized sib pair IBD distribution: Its use in the detection of linkage
    • B.K. Suarez J. Rice T Reich The generalized sib pair IBD distribution: Its use in the detection of linkage Ann. Hum. Genet. London 42 1978 87 94
    • (1978) Ann. Hum. Genet. London , vol.42 , pp. 87-94
    • Suarez, B.K.1    Rice, J.2    Reich, T3
  • 39
    • 0030851777 scopus 로고    scopus 로고
    • True and false positive peaks in genomewide scans: Applications of lengthhiased sampling to linkage mapping
    • J.D. Terwilliger True and false positive peaks in genomewide scans: Applications of lengthhiased sampling to linkage mapping Am. J. Hum. Genet. 61 1997 430 438
    • (1997) Am. J. Hum. Genet. , vol.61 , pp. 430-438
    • Terwilliger, J.D.1
  • 40
    • 0026494911 scopus 로고
    • A haplotype-teased “haplotype relative” risk approach to detect allelic associations
    • J.D. Terwilliger J. Ott A haplotype-teased “haplotype relative” risk approach to detect allelic associations Hum. Hered. 42 1992 337 346
    • (1992) Hum. Hered. , vol.42 , pp. 337-346
    • Terwilliger, J.D.1    Ott, J.2
  • 41
    • 0028067197 scopus 로고
    • Identifying complex disease genes: Progress and paradigms
    • G. Thomson Identifying complex disease genes: Progress and paradigms Nat. Genet. 8 1994 108 110
    • (1994) Nat. Genet. , vol.8 , pp. 108-110
    • Thomson, G.1
  • 42
    • 0029064537 scopus 로고
    • Mapping disease genes: Family-based association studies
    • G. Thomson Mapping disease genes: Family-based association studies Am. J. Hum. Genet. 57 1995 487 498
    • (1995) Am. J. Hum. Genet. , vol.57 , pp. 487-498
    • Thomson, G.1
  • 43
    • 0030666551 scopus 로고    scopus 로고
    • Trade-off between false positives and false negatives in the linkage analysis of complex traits
    • A. Todorov D.C. Rao Trade-off between false positives and false negatives in the linkage analysis of complex traits Genet. Epidemiol. 14 1997 453 464
    • (1997) Genet. Epidemiol. , vol.14 , pp. 453-464
    • Todorov, A.1    Rao, D.C.2
  • 44
    • 0032708761 scopus 로고    scopus 로고
    • Context-dependent associations of the ACEI/D polymorphism with blood pressure
    • S.T. Turner E. Boerwinkle C.E Sing Context-dependent associations of the ACEI/D polymorphism with blood pressure Hypertension 34 1999 773 778 (part 2)
    • (1999) Hypertension , vol.34 , pp. 773-778
    • Turner, S.T.1    Boerwinkle, E.2    Sing, C.E3
  • 45
    • 0031469587 scopus 로고    scopus 로고
    • Genetic analysis of simulated oligogenic traits in nuclear families and extended families
    • E.M. Wijsman C.I. Amos Genetic analysis of simulated oligogenic traits in nuclear families and extended families Genet. Epidemiol. 14 1997 719 735
    • (1997) Genet. Epidemiol. , vol.14 , pp. 719-735
    • Wijsman, E.M.1    Amos, C.I.2
  • 46
    • 0030994211 scopus 로고    scopus 로고
    • Fine-scale genetic mapping based on linkage disequilibrium: Theory and applications
    • M. Xiong S.W. Guo Fine-scale genetic mapping based on linkage disequilibrium: Theory and applications Am. J. Hum. Genet. 60 1997 1513 1531
    • (1997) Am. J. Hum. Genet. , vol.60 , pp. 1513-1531
    • Xiong, M.1    Guo, S.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.