Pharmacology of adenosine receptors in the vasculature

Pharmacology and Therapeutics

Volumn 91, Issue 2, 2001, Pages 133-147

  Tabrizchi, Reza ^a   Bedi, Sonia ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Adenosine; Blood vessels; Circulation; Pharmacology; Receptor subtypes

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE; ADENOSINE DEAMINASE; ADENOSINE KINASE; ADENOSINE RECEPTOR; ADENOSYLHOMOCYSTEINASE; NUCLEOSIDE; OXYGEN; RECEPTOR SUBTYPE;

ARTICLE; BLOOD FLOW; BLOOD VESSEL FUNCTION; BLOOD VESSEL TONE; CARDIOVASCULAR SYSTEM; CELL MEMBRANE TRANSPORT; CELL SECRETION; CONCENTRATION (PARAMETERS); HEART; HEART FUNCTION; HYPOXIA; MAMMAL; METABOLIC RATE; MICROCIRCULATION; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; VASCULAR TISSUE; VASCULARIZATION;

ADENOSINE; ANIMALS; ARTERIES; BLOOD VESSELS; CARDIOVASCULAR PHYSIOLOGY; HUMANS; MAMMALS; MICROCIRCULATION; RECEPTORS, PURINERGIC P1; REGIONAL BLOOD FLOW; SIGNAL TRANSDUCTION;

EID: 0035206081     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(01)00152-8     Document Type: Review

References (153)

1. 3 receptors in rat brain
2. 1 adenosine receptor-mediated Ins(1, 4, 5)P3 generation in allergic rabbit airway smooth muscle
3. Adenosine receptor-mediated relaxation of porcine coronary artery in presence and absence of endothelium
4. 2 receptor agonist, in the isolated rat femoral artery and vein
5. A comparison of A2 adenosine receptor-induced cyclic AMP generation in cerebral cortex and relaxation of pre-contracted aorta
6. 1 receptor
7. 3 receptor (ADORA3) gene
8. Measurement of adenosine metabolism and uptake in smooth muscle and effects of adenosine transport inhibitors
9. Venous adenosine content and vascular responses in dog hind-limb skeletal muscles during twitch contraction
10. Modeling of transendothelial transport
11. 3H]SCH58261 to coronary artery membranes
12. 2A adenosine receptor mediated coronary vasodilatation
13. Glibenclamide attenuates adenosine-induced bradycardia and coronary vasodilatation
14. The role of adenosine in prolong vasodilatation following flow-restricted exercise of canine skeletal muscle
15. Sodium-adenosine cotransport in brush-border membranes from rabbit ileum
16. 2/prostaglandin endoperoxide-receptor activation
17. 1-purinoceptor-mediated vasodilatation and vasoconstriction in hypoxia
18. Rat heart mitochondria release adenosine
19. A basis for distinguishing two types of purinergic receptor
20. Telemetry monitoring of hemodynamic effects of induced over time by adenosine agonists in spontaneously hypertensive rats
21. Is adenosine deaminase involved in adenosine transport?
22. Localization and identity of adenosine deaminase-positive cells in tissues of the young rat and calf
23. 2 receptors mediate tone-dependent responses in feline pulmonary vascular bed
24. 2 adenosine receptor agonists on cardiovascular tissues
25. [3H]2-phenylaminoadenosine ([3H]CV 1808) labels a novel adenosine receptor in rat brain
26. Acute hemodynamic effects of endogenous adenosine in patients with chronic heart failure
27. Effects of adenosine and its analogues on the perfused hind limb artery and vein of anaesthetized dogs
28. 1- agonist in the dog
29. + channels
30. Endogenous adenosine modulates alpha 2- but not alpha 1-adrenergic constriction of coronary arterioles
31. Tissue distribution of adenosine receptor mRNA in the rat
32. Nucleoside-induced arteriolar constriction: A mast cell-dependent response
33. Theophyline increases coronary vascular tone in humans: Evidence for a role of endogenous adenosine in flow regulation
34. Characterization of adenosine receptors in isolated cerebral arteries of cat
35. Effect of adenosine on pulmonary circulation of rabbits
36. Cyclic AMP efflux is regulated by occupancy of adenosine receptor in pig aortic smooth muscle cells
37. Nomenclature and classification of purinoceptors
38. Structure and function of adenosine receptors and their genes
39. α-3
40. Studies of 5′-nucleotidase in the perfused rat heart. Including measurement of the enzyme in perfused skeletal muscle and liver
41. Vectorial production of adenosine by 5′-nucleotidase in the perfused rat heart
42. Age-related changes in adenosine and β-adrenoceptor responsiveness of vascular smooth muscle in man
43. 3 receptors mediate hypotension in the angiotensin II-supported circulation of the pithed rat
44. 2 receptor agonists in the pithed rat: No role for glibenclamide-sensitive potassium channels
45. Microcirculatory responses to adenosine in the newborn pig retina
46. Adenosine increases total venous capacitance in awake instrumented rats
47. 1-purinoceptors
48. Functional characterization of three adenosine receptor types
49. Exogenous adenosine induces flowmotion in skeletal muscle microcirculation of the anesthetized rat
50. Dilation of coronary microvessels by adenosine induced hypotension in dogs
51. Heterogeneous microvascular coronary vasodilation by adenosine and nitroglycerin in dogs
52. Adenine compounds: Cerebrovascular effects in vitro with reference to their possible involvement in migraine
53. A method to evaluate the response of the coronary circulation of perfused rat heart to adenosine
54. Adenosine-induced vasodilation: Receptor characterization in pulmonary circulation
55. 2A receptors mediate coronary microvascular dilation to adenosine: Role of nitric oxide and ATP-sensitive potassium channels
56. S-adenosylhomocysteine hydrolase is an adenosine-binding protein: A target for adenosine
57. Effects of pH on responses to adenosine, CGS 21680, carbachol and nitroprusside in the isolated perfused superior mesenteric arterial bed on the rat
58. Vasodilation produced by forskolin compared with that produced by adenosine in rabbit coronary artery
59. Renovascular effects of adenosine agonists
60. 125I-azidoAPE
61. 2 receptor agonist, in Dahl salt-sensitive rats
62. Adenosine receptors and nucleoside transporter in human brain vasculature
63. 1 receptors
64. 2B receptors
65. Characterization of the adenosine receptor in porcine coronary arteries
66. Elevation of plasma adenosine levels may attenuate the severity of chronic heart failure
67. Transendothelial transport and metabolism of adenosine and inosine in the intact rat aorta
68. Effect of adenosine and glucagon on hepatic blood volume responses to sympathetic nerves
69. Intrarenal actions of the new adenosine agonist CGS 21680A, selective for the A2 receptor
70. Examination of adenosine receptor-mediated relaxation of the pig coronary artery
71. Characterization of adenosine receptors in the rat isolated aorta
72. 2a receptors
73. ATP channel
74. 3 receptors: Pharmacological properties, species differences and receptor functions
75. Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices
76. Adenosine metabolism in the guinea pig heart: The role of cytosolic S-adenosyl-L-homocysteine hydrolase, 5′-nucleotidase and adenosine kinase
77. 2a receptors
78. 2-adrenoceptor. Evidence that adenylate cyclase is the limiting component for receptor-mediated stimulation of adenylate cyclase activity
79. 2 receptor in coronary artery
80. Purine salvage pathways in myocardium
81. 2-adenosine receptor to stimulatory guanine nucleotide-binding-protein in bovine brain striatum
82. 2A receptors in human and porcine cardiovascular tissue
83. 2B receptors in the guinea pig aorta
84. 6-cyclopentyladenosine
85. Characterization of adenosine receptors in human pulmonary arteries
86. 1-selective adenosine agonist, RG14202
87. The role of adenosine in dilator responses induced in arterioles and venules of rat skeletal muscle by systemic hypoxia
88. Adenosine metabolism in microvessels from heart and brain
89. Evidence for the involvement of cyclic GMP in adenosine-induced, age-dependent vasodilatation
90. o
91. Reactivity of isolated canine cerebral arteries to adenine nucleotide and adenosine
92. Effects of adenosine and its analogues on isolated intracerebral arterioles. Extraluminal and intraluminal application
93. 5′-Nucleotidase from rat heart
94. Pharmacological probes for A1 and A2 adenosine receptors in vivo in feline pulmonary vascular bed
95. 2A receptor agonist, CGS 21680, on blood pressure, cardiac index and arterial conductance in anaesthetized rats
96. 2A receptor agonist, on cardiac output and vascular resistance in acute heart failure in anaesthetized rats
97. 2A receptor agonist, CGS 21680, in chronic heart failure in anaesthetized rats
98. Adenosine formation. Evidence for a direct biochemical link with energy metabolism
99. Glibenclamide reduces the coronary vasoactivity of adenosine receptor agonists
100. 1 receptors
101. Adenosine receptor subtypes: Characterization and therapeutic regulation
102. 2B receptors in cultured human and porcine coronary artery endothelial cells
103. Ligand binding to the adenosine analogue binding protein on the rabbit erythrocyte
104. Compartmentalization of the adenosine pool of dog and rat heart
105. 3 adenosine receptor
106. Distinct cardioprotective effects of adenosine mediated by differential coupling of receptor subtypes to phospholipases C and D
107. 3 receptor
108. Adenosine and tubercidin binding and transport in Chinese hamster ovary and Novikoff rat hepatoma cells
109. Activation of multiple sites by adenosine analogues in the rat isolated aorta
110. Characterisation of adenosine receptors mediating relaxation in hamster isolated aorta
111. Activation of two sites by adenosine receptor agonist to cause relaxation in rat isolated mesenteric artery
112. Adenosine and free-flow functional hyperemia in striated muscle
113. Adenosine receptors, cyclic AMP accumulation, and DNA-synthesis in aortic smooth muscle cell cultures of adult and neonatal rats
114. Action of adenosine and characterization of adenosine receptors in human placental vasculature
115. Myocardial nucleotide transport
116. 2-purinoceptors to the control of vascular tone in the rat isolated mesenteric arterial bed
117. G protein subserve relaxations mediated by adenosine receptors in human coronary artery
118. cDNA cloning and sequence analysis of the human A3 adenosine receptor
119. Compartmentation of cardiac adenine nucleotides and formation of adenosine
120. Role of S-adenosylhomocysteine hydrolase in adenosine metabolism in mammalian heart
121. Localization of adenosine deaminase and adenosine deaminase complexing protein in rabbit heart. Implications for adenosine metabolism
122. Different sites of adenosine formation in the heart
123. Cardiac endothelial transport and metabolism of adenosine and inosine
124. Endothelial adenosine transporter characterization in perfused guinea-pig hearts
125. 3 adenosine receptor
126. The effect of ATP and related compounds on spontaneous mechanical activity in the rat portal vein
127. Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans
128. Role of adenosine in adipose tissue circulation
129. The antilipolytic effect of endogenous and exogenous adenosine in canine adipose tissue in situ
130. Regulation of adenosine formation by the heart
131. Capillary transport of adenosine
132. 2 receptors
133. 2 receptors in guinea-pig aorta
134. 2 adenosine receptors in the skin microcirculation
135. Adenosine receptors mediate both contractile and relaxant effects of adenosine in main pulmonary artery of guinea-pig
136. Effects of adenosine and adenosine analogues on mean circulatory filling pressure and cardiac output in anesthetized rats
137. The influence of tumour necrosis factor-α on the cardiovascular system of anaesthetized rats
138. Vasodilatation produced by adenosine in isolated rat perfused mesenteric artery: A role for endothelium
139. Effect of adenosine on adrenergic neurotransmission and modulation by endothelium in canine pulmonary artery
140. ATP in in vitro perfused hydronephrotic rat kidney
141. Responses to adenine nucleotides and related compounds of isolated dog cerebral, coronary and mesenteric arteries
142. Cloned receptors and cardiovascular responses to adenosine
143. 2 adenosine receptor
144. Binding of adenosine to intracellular S-adenosylhomocysteine hydrolase in isolated rat hepatocytes
145. Action of adenosine and adenine nucleotides on dogs' isolated veins
146. Hypoxic vasodilatation in isolated, perfused guinea-pig heart: An analysis of the underlying mechanisms
147. Relaxant effects of ATP and adenosine on canine large and small coronary arteries in vitro
148. 2 receptors and alpha1-adrenoceptors in the rabbit isolated aorta
149. The mechanism of adenosine production in rat polymorphonuclear leucocytes
150. Regulation of soluble 5′-nucleotidase I from rabbit heart
151. Effect of adenosine on isolated afferent arterioles
152. 3-subtype adenosine receptor is highly expressed in rat vascular smooth muscle cells: Its role in attenuating adenosine-induced increase in cAMP
153. 3 adenosine receptor in determining tissue levels of cAMP and blood pressure: Studies in knock-out mice