Binding of the novel nonxanthine A(2A) adenosine receptor antagonist [3H]SCH58261 to coronary artery membranes

Circulation Research

Volumn 79, Issue 6, 1996, Pages 1153-1160

  Belardinelli, Luiz ^a   Shryock, John C ^a   Ruble, Jackie ^a   Monopoli, Angela ^b   Dionisotti, Silvio ^b   Ongini, Ennio ^b   Dennis, Donn M ^a   Baker, Stephen P ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b San Raffaele Science Park   (Italy)

Author keywords

A(2A) adenosine receptor; A(2A) receptor antagonist; coronary artery; radioligand; SCH58261

Indexed keywords

5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE A2 RECEPTOR; ADENOSINE A2 RECEPTOR ANTAGONIST; RECEPTOR SUBTYPE;

ANIMAL CELL; ARTICLE; BINDING SITE; CONCENTRATION RESPONSE; CORONARY ARTERY; DISSOCIATION CONSTANT; LIGAND BINDING; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY;

EID: 0029806824     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.79.6.1153     Document Type: Article

References (24)

1. Berne RM. Metabolic regulation of blood flow. Circ Res. 1964;14-15(suppl 1):261-268.
2. Mustafa SJ, Marala R, Abebe W, Jeansonne N, Olanrewaju H, Hussain T. Coronary adenosine receptors: subtypes, localization, and function. In: Belardinelli L, Pelleg A, eds. Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology. Boston, Mass: Kluwer Academic Publishers; 1995:229-239.
3. Olsson RA, Pearson JD. Cardiovascular purinoceptors. Physiol Rev. 1990;70:761-845.
4. Dutta P, Mustafa SJ. Binding of adenosine to the crude plasma membrane fraction isolated from dog coronary and carotid arteries. J Pharmacol Exp Ther. 1980;214:496-502.
5. 1. J Pharmacol Exp Ther. 1996;276:284-288.
6. 2 receptor antagonist, to rat brain membranes. Mol Pharmacol. 1994;46:817-822.
7. 2A adenosine receptor. Mol Pharmacol. 1995;48:970-974.
8. 2A adenosine receptor antagonist, to rat striatal membranes. Br J Pharmacol. 1996;117:1381-1386.
9. 2A adenosine receptor antagonists. Bioorg Med Chem Lett. 1994;4:2539-2544.
10. Harper JF, Brooker G. Femtomole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2′0 acetylation by acetic anhydride in aqueous solution. J Cyclic Nucleotide Res. 1975;1:207-218.
11. 50) of an enzymatic reaction. Biochem Pharmacol. 1973;22:3099-3108.
12. 1-adenosine receptors in guinea pig atrioventricular node. Am J Physiol. 1992;262:H661-H671.
13. 3H]SCH58261. J Pharmacol Exp Ther. 1996;278:1209-1214.
14. 2A adenosine receptor antagonist. J Pharmacol Exp Ther. 1996;276:398-404.
15. 2A receptor antagonists. In: Belardinelli L, Pelleg A, eds. Adenosine and Adenine Nucleotides: from Molecular Biology to Integrative Physiology. Boston, Mass: Kluwer Academic Publishers; 1995:241-248.
16. Abebe W, Hussain T, Olanrewaju H, Mustafa SJ. Role of nitric oxide in adenosine receptor-mediated relaxation of porcine coronary artery. Am J Physiol. 1995;269:H1672-H1678.
17. 3H]NECA in rat striatal membranes. Mol Pharmacol. 1986;29:331-346.
18. 2 receptors in rat brain. J Pharmacol Exp Ther. 1989;251:888-893.
19. Williams M, Abreu M, Jarvis F, Noronha-Blob L. Characterization of adenosine receptors in the PC12 pheochromocytoma cell line using radioligand binding: evidence for A-2 selectivity. J Neurochem. 1987;48:498-502.
20. 2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: characterization with radioligand binding and by activation of adenylate cyclase. Mol Pharmacol. 1992;41:352-359.
21. 2-adenosine receptors using radioligand binding and photoaffinity labeling. J Recept Res. 1992;12:149-169.
22. 2 adenosine receptors of human platelets. FEBS Lett. 1986;199:269-274.
23. 2 receptor antagonist. Eur J Pharmacol. 1994;267:335-341.
24. 125I]iodophenyl)ethylamino]-adenosine. Mol Pharmacol. 1995;47:307-313.