Activation of multiple sites by adenosine analogues in the rat isolated aorta

British Journal of Pharmacology

Volumn 118, Issue 6, 1996, Pages 1509-1517

  Prentice, D J ^a   Hourani, S M O ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Adenosine; Endothelium; Nitric oxide; Purinoceptors; Rat aorta; Xanthines

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2 RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE DERIVATIVE; N [2 (DIMETHYLAMINO)ETHYL] N METHYL 4 (1,3 DIPROPYLXANTHIN 8 YL)BENZENESULFONAMIDE; N(G) NITROARGININE METHYL ESTER; PARTIAL AGONIST; PHENYLISOPROPYLADENOSINE; THEOPHYLLINE DERIVATIVE; XANTHENE DERIVATIVE;

ANIMAL TISSUE; AORTA; ARTERY DILATATION; ARTICLE; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR BLOCKING; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

EID: 0029889768     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15567.x     Document Type: Article

References (22)

1. BAILEY, S.J. & HOURANI, S.M.O. (1992). Effects of purines on the longitudinal muscle of the rat colon. Br. J. Pharmacol., 105, 885-892.
2. BLACK, J.W. & SHANKLEY, N.P. (1985). The isolated stomach preparation of the mouse: a physiological unit for pharmacological analysis. Br. J. Pharmacol., 86, 571-579.
3. BRACKETT, L.E. & DALY, J.W. (1991). Relaxant effects of adenosine analogues on guinea pig trachea in vitro: Xanthine sensitive and xanthine-insensitive mechanisms. J. Pharmacol. Exp. Ther., 257, 205-213.
4. 2badenosine receptor in NIH 3T3 fibroblasts. Biochem. Pharmacol., 47, 801-814.
5. 2 receptors. Naunyn Schmied. Arch. Pharmacol., 335, 64-69.
6. 2 receptor and an intracellular site. Eur. J. Pharmacol., 96, 61-69.
7. CRISTALLI G, VITTORI, S., THOMPSON, R.D., PADGETT, W.L., SHI, D., DALY, J.W. & OLSSON, R.A. (1994). Inhibition of platelet aggregation by adenosine receptor agonists. Naunyn Schmied. Arch. Pharmacol., 349, 644-650.
8. DALY, J.W., BUTTS-LAMB, P. & PADGETT, W. (1983). Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines. Cellular Molecular Neurobiology, 3, 69-80.
9. 2) receptors. In Comprehensive Medicinal Chemistry. Membranes and Receptors. ed. Emmett, J.C. Oxford: Pergamon Press.
10. 3-adenosine receptors: design of selective ligands and therapeutic prospects. Drugs of the Future, 20, 689-699.
11. LEWIS, C.D., HOURANI, S.M.O., LONG, C.J. & COLLIS, M.G. (1994). Characterisation of adenosine receptors in the rat isolated aorta. Gen. Pharmacol., 25, 1381-1387.
12. LINDEN, J., TUCKER, T.L., ROBEVA, A.S., GRABER, S.G. & MUNISHI, T. (1993). Properties of recombinant adenosine receptors. Drug. Devel. Res., 28, 232-236.
13. LONDOS, C., COOPER, D.M.F. & WOLFF, J. (1980). Subclasses of external adenosine receptors. Proc. Natl. Acad. Sci. U.S.A., 77, 2551-2554.
14. 2B receptors in the guinea-pig aorta. Eur. J. Pharmacol., 216, 235-242.
15. MORITOKI, H., MATSUGI, T., TAKASE, H., UEEDA, H. & TANIOKA, A. (1990). Evidence for the involvement of cyclic GMP in adenosine-induced, age-dependent vasodilation. Br. J. Pharmacol., 100, 569-575.
16. 2a selective adenosine receptor antagonist. Br. J. Pharmacol., 115, 1096-1102.
17. PRENTICE, D.J., SHANKLEY, N.P. & BLACK, J.W. (1995). Pharmacological analysis of the interaction between purinoceptor agonists and antagonists in the guinea-pig taenia caecum. Br. J. Pharmacol., 115, 549-556.
18. 2 purinoceptors are involved in endothelium-dependent relaxation of the rat thoracic aorta. Br. J. Pharmacol., 100, 576-580.
19. TUCKER, A.L. & LINDEN, J. (1993). Cloned receptors and cardiovascular responses to adenosine. Cardiovasc. Res., 27, 62-67.
20. VAN CALKER, D., MULLER, M. & HAMPRECHT, B. (1979). Adenosine regulates via two different types of receptors the accumulation of cyclic AMP in cultured brain cells. J. Neurochem., 33, 999-1005.
21. WALLENSTEIN, S., ZUCKER, C.L. & FLEISS, J.L. (1980). Some statistical methods useful in circulation research. Circ. Res., 47, 1-9.
22. 3 adenosine receptor. Proc. Natl. Acad. Sci. U.S.A., 89, 7432-7436.