Cardiac endothelial transport and metabolism of adenosine and inosine

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 277, Issue 3 46-3, 1999, Pages

  Schwartz, Lisa M ^a,b   Bukowski, Thomas R ^a,c   Revkin, James H ^a,d   Bassingthwaighte, James B ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^c ZYMOGENETICS INC   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Biological transport; Blood tissue exchange; Capillary endothelial permeability; Guinea pig; Isolated heart; Multiple indicator dilution technique; Nucleoside transport; Rabbit; Species specificity

Indexed keywords

ADENOSINE DERIVATIVE; ALBUMIN; HYPOXANTHINE; INOSINE; IODINE 131; PURINE NUCLEOSIDE; URIC ACID; XANTHINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CORONARY ARTERY BLOOD FLOW; ENDOTHELIUM CELL; GUINEA PIG; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN TRANSPORT; RABBIT; SPECIES DIFFERENCE; TRANSPORT AT THE CELLULAR LEVEL;

EID: 0032887856     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.277.3.h1241     Document Type: Article

References (53)

1. Bardenheuer, H., B. Whelton, and H. V. Sparks, Jr. Adenosine release by the isolated guinea pig heart in response to isoproterenol, acetylcholine, and acidosis: the minimal role of vascular endothelium. Circ. Res. 61: 594-600, 1987.
2. Bassingthwaighte, J. B., I. S. Chan, and C. Y. Wang. Computationally efficient algorithms for capillary convection-permeation-diffusion models for blood-tissue exchange. Ann. Biomed. Eng. 20: 687-725, 1992.
3. Bassingthwaighte, J. B., and C. A. Goresky. Modeling in the analysis of solute and water exchange in the microvasculature. In: Handbook of Physiology. The Cardiovascular System. The Microcirculation. Bethesda, MD: Am. Physiol. Soc., 1984, sect. 2, vol. IV, pt. 1, chapt. 13, p. 549-626.
4. Bassingthwaighte, J. B., M. A. Malone, T. C. Moffett, R. B. King, S. E. Little, J. M. Link, and K. A. Krohn. Validity of microsphere depositions for regional myocardial flows. Am. J. Physiol. 253 (Heart Circ. Physiol. 22): H184-H193, 1987.
5. Bassingthwaighte, J. B., and H. V. Sparks. Indicator dilution estimation of capillary endothelial transport. Annu. Rev. Physiol. 48: 321-334, 1986.
6. Bassingthwaighte, J. B., C. Y. Wang, and I. S. Chan. Blood-tissue exchange via transport and transformation by endothelial cells. Circ. Res. 65: 997-1020, 1989.
7. Bassingthwaighte, J. B., T. Yipintsoi, and R. B. Harvey. Microvasculature of the dog left ventricular myocardium. Microvasc. Res. 7: 229-249, 1974.
8. Becker, B. F., and E. Gerlach. Uric acid, the major catabolite of cardiac adenine nucleotides and adenosine, originates in the coronary endothelium. In: Topics and Perspectives in Adenosine Research, edited by E. Gerlach and B. F. Becker. Berlin: Springer, 1987, p. 209-222.
9. Berne, R. M., R. M. Knabb, S. W. Ely, and R. Rubio. Adenosine in the local regulation of blood flow: a brief overview. Federation Proc. 42: 3136-3142, 1983.
10. Borgers, M., and F. Thone. Species differences in adenosine metabolic sites in the heart. Histochem. J. 24: 445-452, 1992.
11. Bukowski, T., T. C. Moffett, J. H. Revkin, J. D. Ploger, and J. B. Bassingthwaighte. Triple-label β liquid scintillation counting. Anal. Biochem. 204: 171-180, 1992.
12. Caldwell, J. H., G. V. Martin, G. M. Raymond, and J. B. Bassingthwaighte. Regional myocardial flow and capillary permeability-surface area products are nearly proportional. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H654-H666, 1994.
13. Cass, C. E., and A. R. P. Paterson. Inhibition by nitrobenzylthioinosine of uptake of adenosine, 2′-deoxyadenosine and 9-β-D-arabinofuranosyladenine by human and mouse erythrocytes. Biochem. Pharmacol. 24: 1989-1993, 1975.
14. Catravas, J. D. Removal of adenosine from the rabbit pulmonary circulation, in vivo and in vitro. Circ. Res. 54: 603-611 1984.
15. Chan, I. S., A. A. Goldstein, and J. B. Bassingthwaighte. SENSOP: a derivative-free solver for non-linear least squares with sensitivity scaling. Ann. Biomed. Eng. 21: 621-631, 1993.
16. Deussen, A., G. Möser, and J. Schrader. Contribution of coronary endothelial cells to cardiac adenosine production. Pflügers Arch. 406: 608-614, 1986.
17. Dieterle, Y., C. Ody, A. Ehrensberger, H. Stalder, and A. F. Junod. Metabolism and uptake of adenosine triphosphate and adenosine by porcine aortic and pulmonary endothelial cells and fibroblasts in culture. Cire. Res. 42: 869-876, 1978.
18. Downey, J. M., D. J. Hearse, and D. M. Yellon. The role of xanthine oxidase during myocardial ischemia in several species including man. J. Mol. Cell. Cardiol. 20: 55-63, 1988.
19. Downey, J. M., T. Miura, L. J. Eddy, D. E. Chambers, T. Mellert, D. J. Hearse, and D. M. Yellon. Xanthine oxidase is not a source of free radicals in the ischemic rabbit heart. J. Mol. Cell. Cardiol. 19: 1053-1060, 1987.
20. Edward, J. T. Molecular volumes and the Stokes-Einstein equation. J. Chem. Ed. 47: 261-270, 1970.
21. Ely, S. W., and R. M. Berne. Protective effects of adenosine in myocardial ischemia. Circulation 85: 893-904, 1992.
22. Feigl, E. O. Coronary physiology. Physiol. Rev. 63: 1-205, 1983.
23. Gao, Z. P., H. F. Downey, W. L. Fan, and R. T. Mallet. Does interstitial adenosine mediate acute hibernation of guinea pig myocardium? Cardiovasc. Res. 29: 796-804, 1995.
24. Gerlach, E., S. Nees, and B. F. Becker. The vascular endothelium: a survey of some newly evolving biochemical and physiological features. Basic Res. Cardiol. 80: 459-474, 1985.
25. Gonzalez, F., and J. B. Bassingthwaighte. Heterogeneities in regional volumes of distribution and flows in the rabbit heart. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H1012-H1024, 1990.
26. Gorman, M. W., J. B. Bassingthwaighte, R. A. Olsson, and H. V. Sparks. Endothelial cell uptake of adenosine in canine skeletal muscle. Am. J. Physiol. 250 (Heart Circ. Physiol. 19): H482-H489, 1986.
27. Grum, C. M., L. H. Ketai, C. L. Myers, and M. Shlafer. Purine efflux after cardiac ischemia: relevance to allopurinol cardioprotection. Am. J. Physiol. 252 (Heart Circ. Physiol. 21): H368-H373, 1987.
28. Harmsen, E., J. W. deJong, and P. W. Seriuys. Hypoxanthine production by ischemic heart demonstrated by pressure liquid chromatography of blood purine nucleosides and oxypurines. Clin. Chim. Acta 115: 73-84, 1981.
29. Hellewell, P. G., and J. D. Pearson. Different uptake profiles for prostaglandin Fd2αu and adenosine in the piglet pulmonary circulation (Abstract). J. Physiol. (Lond.) 334: 102P, 1983.
30. Hopkins, S. V., and R. G. Goldie. A species difference in the uptake of adenosine by heart. Biochem. Pharmacol. 20: 3359-3365, 1971.
31. Jarvis, S. M., J. R. Hammond, A. R. P. Paterson, and A. S. Clanachan. Species differences in nucleoside transport: a study of uridine transport and nitrobenzylthioinosine binding by mammalian erythrocytes. Biochem. J. 208: 83-88, 1982.
32. Jarvis, S. M., and J. D. Young. Nucleoside translocation in sheep reticulocytes and fetal erythrocytes: a proposed model for the nucleoside transporter. J. Physiol. (Lond.) 324: 47-66, 1982.
33. Kroll, K., T. R. Bukowski, L. M. Schwartz, D. Knoepfler, and J. B. Bassingthwaighte. Capillary endothelial transport of uric acid in the guinea pig heart. Am. J. Physiol. 262 (Heart Circ. Physiol. 31): H420-H431, 1992.
34. Kroll, K., R. B. King, J. C. Caldwell, K. A. Krohn, C. A. Rhodes, and J. B. Bassingthwaighte. Distributed non-linear modeling of PET adrenoreceptor ligand. Ann. Biomed. Eng. 23: S-64, 1995.
35. Kroll, K., and D. W. Stepp. Adenosine kinetics in the canine coronary circulation. Am. J. Physiol. 270 (Heart Circ. Physiol. 39): H1469-H1483, 1996.
36. Kuikka, J., M. Levin, and J. B. Bassingthwaighte. Multiple tracer dilution estimates of D- and 2-deoxy-D-glucose uptake by the heart. Am. J. Physiol. 250 (Heart Circ. Physiol. 19): H29-H42, 1986.
37. McConahey, P. J., and F. J. Dixon. A method of trace iodination of proteins for immunologic studies. Int. Arch. Allergy 29: 185-189, 1966.
38. Moffett, T. C., I. S. Chan, and J. B. Bassingthwaighte. Myocardial serotonin exchange: negligible uptake by capillary endothelium. Am. J. Physiol. 254 (Heart Circ. Physiol. 23): H570-H577, 1988.
39. Mohrman, D. E., and L. J. Heller. Transcapillary adenosine transport in isolated guinea pig and rat hearts. Am. J. Physiol. 259 (Heart Circ. Physiol. 28): H772-H783, 1990.
40. Nees, S., V. Herzog, B. F. Becker, M. Böck, C. Des Rosiers, and E. Gerlach. The coronary endothelium: a highly active metabolic barrier for adenosine. Basic Res. Cardiol. 80: 515-529, 1985.
41. Olsson, R. A., E. M. Khouri, J. L. Bedynek, Jr., and J. McLean. Coronary vasoactivity of adenosine by pig aortic endothelial and smooth muscle cells in culture. Circ. Res. 45: 468-478, 1979.
42. Parkinson, F. E., and A. S. Clanachan. Heterogeneity of nucleoside transport inhibitory sites in heart: a quantitative autoradiographical analysis. Br. J. Pharmacol. 97: 361-370, 1989.
43. Pearson, J. D., J. S. Carleton, A. Hutchings, and J. L. Gordon. Uptake and metabolism of adenosine by pig aortic endothelial and smooth-muscle cells in culture. Biochem. J. 170: 265-271, 1978.
44. Plagemann, P. G. W., and R. M. Wohlhueter. Kinetics of nucleoside transport in human erythrocytes alterations during blood preservation. Biochim. Biophys. Acta 778: 176-184, 1984.
45. Plagemann, P. G. W., R. M. Wohlhueter, and J. Erbe. Nucleoside transport in human erythrocytes: a simple carrier with directional symmetry and differential mobility of loaded and empty carrier. J. Biol. Chem. 257: 12069-12074, 1982.
46. Safford, R. E., and J. B. Bassingthwaighte. Calcium diffusion in transient and steady states in muscle. Biophys. J. 20: 113-136, 1977.
47. Schrader, J. Sites of action and production of adenosine in the heart. In: Purinergic Receptors, edited by G. Burnstock. London: Chapman and Hall, 1981, vol. 12, p. 121-162. (Receptors and Recognition, Ser. B)
48. Stepp, D. W., R. van Bibber, K. Kroll, and E. O. Feigl. Quantitative relation between interstitial adenosine concentration and coronary blood flow. Circ. Res. 79: 601-610, 1996.
49. Vargas, F. F., and J. A. Johnson. An estimate of reflection coefficients for rabbit heart capillaries. J. Gen. Physiol. 47: 667-677, 1964.
50. Vargas, F. F., and J. A. Johnson. Permeability of rabbit heart capillaries to non-electrolytes. Am. J. Physiol. 213: 87-93, 1967.
51. Wangler, R. D., M. W. Gorman, C. Y. Wang, D. F. DeWitt, I. S. Chan, J. B. Bassingthwaighte, and H. V. Sparks. Transcapillary adenosine transport and interstitial adenosine concentration in guinea pig hearts. Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H89-H106, 1989.
52. Williams, E. F., P. H. Barker, and A. S. Clanachan. Nucleoside transport in heart: species differences in nitrobenzylthioinosine binding, adenosine accumulation, and drug-induced potentiation of adenosine action. Can. J. Physiol. Pharmacol. 62: 31-37, 1984.
53. Winkler, B., R. Seiler, and W. Schaper. Single passage of adenosine in the rabbit heart at low and high adenosine concentrations (Abstract). FASEB J. 2: A1883, 1988.