N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) suppresses microglial inducible nitric oxide synthase (iNOS) expression and activity induced by interferon-γ (IFN-γ)

British Journal of Pharmacology

Volumn 134, Issue 6, 2001, Pages 1279-1284

  Platten, M ^a   Wick, W ^a   Wischhusen, J ^a   Weller, M ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Inducible nitric oxide synthase; Inhibitory B; Interferon ; Microglia; Nitric oxide; Nuclear factor B; Tranilast

Indexed keywords

GAMMA INTERFERON; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TRANILAST;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; ENZYME INHIBITION; ENZYME REPRESSION; GENE EXPRESSION REGULATION; MICROGLIA; MONOCYTE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR GENE; WESTERN BLOTTING;

EID: 0035203684     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704373     Document Type: Article

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