L-arginine for the prevention and treatment of coronary artery disease

Coronary Artery Disease

Volumn 12, Issue 7, 2001, Pages 535-539

  Blum, Arnon ^a   Cannon III, Richard O ^b  

^a Poriya Hospital   (Israel)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Atherosclerosis; Endothelium; L arginine; Nitric oxide

Indexed keywords

ARGININE; CALCIUM; CELL ADHESION MOLECULE; CYCLIC GMP DEPENDENT PROTEIN KINASE; NITRIC OXIDE;

CLINICAL TRIAL; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; DRUG EFFECT; DRUG EFFICACY; HOMEOSTASIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; REVIEW; VASODILATATION;

ARGININE; CORONARY DISEASE; HUMANS; NITRIC OXIDE;

EID: 0035192517     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019501-200111000-00002     Document Type: Review

References (56)

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2. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
3. Vascular endothelial cells synthesize nitric oxide from L-arginine
4. Endothelium-derived relaxing factor from pulmonary artery and vein posses pharmacologic and chemical properties identical to those of nitric oxide radical
5. A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation
6. Nitric oxide synthesized from L-arginine regulates vascular tone in the coronary circulation of the rabbit
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8. Nitric oxide activity in the human coronary circulation. Impact of risk factors for atherosclerosis
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13. Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta
14. Expression of inducible nitric oxide synthase in T lymphocytes and macrophages of cholesterol-fed rabbits
15. Histochemical evidence for inducible nitric oxide synthase in advanced but non-ruptured human atherosclerotic carotid arteries
16. Analysis of lysophosphatidylcholine-induced endothelial dysfunction
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19. Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion
20. Tetrahydrobiopterin regulates superoxide and nitric oxide generation by recombinant endothelial nitric oxide synthesis
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22. Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans
23. Effect of the Glu298asp mutation of the endothelial nitric oxide synthase gene on human coronary microvascular function
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28. Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease
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32. L-Arginine attenuates platelet reactivity in hypercholesterolemic rabbits
33. Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine
34. Supplementation of hypercholesterolemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production
35. Control of accelerated vein graft atheroma with the nitric oxide precursor: L-arginine
36. L-Arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice
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39. Does acute improvement of endothelial dysfunction in coronary artery disease improve myocardial ischemia? A double-blind comparison of parenteral D- and L-arginine
40. Effects of infusion of L-arginine into the left anterior descending coronary artery on acetylcholine-induced vasoocnstriction of human atheromatous coronary arteries
41. Effect of L-arginine on human coronary endothelium-dependent and physiologic vasodilation
42. Coronary stenosis dilation induced by L-arginine
43. Effects of infusion of L-arginine on exercise-induced myocardial ischemic ST-segment changes and capacity to exercise of patients with stable angina pectoris
44. Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults
45. Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans
46. L-Arginine reduces human monocyte adhesion to vascular endothelium and endothelial expression of cell adhesion molecules
47. Oral L-arginine improves endothelium-dependent dilation and reduces monocyte adhesion to endothelial cells in young men with coronary artery disease
48. Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans
49. Effect of supplemental oral L-arginine on exercise capacity in patients with stable angina pectoris
50. Clinical and inflammatory effects of dietary L-arginine in patients with intractable angina pectoris
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52. L-Arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans
53. Early endothelial dysfunction in adults at risk from atherosclerosis: Different responses to L-arginine
54. Cigarette smoking is associated with increased human monocyte adhesion to endothelial cells: Reversibility with oral L L-arginine but not vitamin C
55. Effects of oral L-arginine on endothelium-dependent vasodilation and markers of inflammation in healthy postmenopausal women
56. Atorvastatin but not L-arginine improves endothelial function in type I diabetes mellitus: A double-blind study