Src family kinases are required for prolactin induction of cell proliferation

Molecular Biology of the Cell

Volumn 12, Issue 7, 2001, Pages 2171-2183

  Fresno Vara, J A ^a   Dominguez Caceres M A ^a   Silva, A ^a   Martin Perez J ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

HERBIMYCIN A; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROLACTIN; PROTEIN; PROTEIN SAM68; PROTEIN SERINE KINASE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; PROTEIN TYROSINE PHOSPHATASE; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; GENE INDUCTION; HORMONE ACTION; MOUSE; NONHUMAN; ONCOGENE C JUN; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALIA; JANUS;

EID: 0035172222     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.12.7.2171     Document Type: Article

References (72)

1. Reactive oxygen species activate p90 ribosomal S6 kinase via fyn and Ras
2. Prolactin induced tyrosine phosphorylation of p59fyn may mediate phosphatidylinositol 3-kinase activation in Nb2 cells
3. PTP1D is a positive regulator of the prolactin signal leading to beta- casein promoter activation
4. A role for Sam68 in cell cycle progression antagonized by a spliced variant within the KH domain
5. Myc but not Fos rescue of PDGF signaling block caused by kinase- inactive Src
6. Structural design and molecular evolution of a cytokine receptor superfamily
7. The ornithine decarboxylase gene is a transcriptional target of c-Myc
8. Prolactin receptor is associated with c-src kinase in rat liver
9. Prolactin activates tyrosyl phosphorylation of insulin receptor substrate 1 and phosphatidylinositol-3-OH kinase
10. Prolactin (PRL) and its receptor: Actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice
11. IL-2 signaling in human monocytes involves the phosphorylation and activation of p59hck
12. p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes
13. Signaling via Src family kinases is required for normal internalization of the receptor c-Kit
14. Regulation, substrates and functions of src
15. The protein tyrosine kinase P59fyn is associated with prolactin (PRL) receptor and is activated by PRL stimulation of T-lymphocytes
16. Platelet-derived-growth-factor stimulation of the p42/p44 mitogen- activated protein kinase pathway in airway smooth muscle: Role of pertussis-toxin-sensitive G-proteins, c-Src tyrosine kinases and phosphoinositide 3-kinase
17. Src-related protein tyrosine kinases in hematopoiesis
18. Interleukin-3 induces association of the protein-tyrosine phosphatase SHP2 and phosphatidylinositol 3-kinase with a 100-kDa tyrosine-phosphorylated protein in hemopoietic cells
19. Growth signaling and JAK2 association mediated by membrane-proximal cytoplasmic regions of prolactin receptors
20. Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580
21. Regulation of gene expression by prolactin
22. Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E- binding protein 1 phosphorylation
23. Identification of JAK protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin- erythropoietin receptor chimera expressed in lymphoid cells
24. SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases
25. Stimulation of c-Src by prolactin is independent of Jak2
26. A target for Src in mitosis
27. Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling
28. Involvement of SHP-2 in multiple aspects of IL-2 signaling: Evidence for a positive regulatory role
29. Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription
30. Prolactin signal transduction to milk protein genes: Carboxy-terminal part of the prolactin receptor and its tyrosine phosphorylation are not obligatory for JAK2 and STAT5 activation
31. New role for shc in activation of the phosphatidylinositol 3-kinase/Akt pathway
32. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor: Study of Lck- and FynT-dependent T cell activation
33. Transcriptional regulation by the helix bundle peptide hormones: Growth hormone, prolactin, and hematopoietic cytokines
34. c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism
35. AP-1 function and regulation
36. Fyn membrane localization is necessary to induce the constitutive tyrosine phosphorylation of Sam68 in the nucleus of T lymphocytes
37. Identification of Grb10 as a direct substrate for members of the Src tyrosine kinase family
38. Prolactin-induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase JAK2
39. Proline-rich sequence-mediated Jak2 association to the prolactin receptor is required but not sufficient for signal transduction
40. Signaling through phosphoinositide 3-kinases: The lipids take center stage
41. A new function for a phosphotyrosine phosphatase: Linking GRB2-Sos to a receptor tyrosine kinase
42. Interleukin-3 induces the association of the inositol 5-phosphatase SHIP with SHP2
43. Structural basis for selective inhibition of Src family kinases by PP1
44. The human p62 cDNA encodes Sam68 and not the RasGAP-associated p62 protein
45. Knockouts of Src-family kinases: Stiff bones, wimpy T cells, and bad memories
46. pEF-BOS, a powerful mammalian expression vector
47. Influence of prolactin on the differentiation of mouse B-lymphoid precursors
48. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
49. Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinase
50. The catalytic activity of the src family kinases is required to disrupt cadherin-dependent cell-cell contacts
51. Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo
52. A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
53. Jak2 is essential for signaling through a variety of cytokine receptors
54. High affinity IgG receptor activation of Src family kinases is required for modulation of the Shc-Grb2-Sos complex and the downstream activation of the nicotinamide adenine dinucleotide phosphate (reduced) oxidase
55. New impressions of Src and Hck
56. Src homology 2 protein tyrosine phosphatase (SHPTP2)/Src homology 2 phosphatase 2 (SHP2) tyrosine phosphatase is a positive regulator of the interleukin 5 receptor signal transduction pathways leading to the prolongation of eosinophil survival
57. The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor
58. Rapid stimulation of mitogen-activated protein kinase of rat liver by prolactin
59. Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit
60. Contribution of both STAT and SRF/TCF to c-fos promoter activation by granulocyte-macrophage colony-stimulating factor
61. DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases
62. Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor
63. Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: Summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events
64. Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice
65. p53 is not required for regulation of apoptosis or radioprotection by interleukin-3
66. Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B
67. Cytokine signaling through nonreceptor protein tyrosine kinases
68. Cellular functions regulated by Src family kinases
69. The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells
70. Cytokine receptor signal transduction and the control of hematopoietic cell development
71. Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3′-kinase
72. JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone