Fyn membrane localization is necessary to induce the constitutive tyrosine phosphorylation of Sam68 in the nucleus of T lymphocytes

Journal of Immunology

Volumn 162, Issue 12, 1999, Pages 7224-7232

  Lang, Valérie ^a   Semichon, Monique ^b   Michel, Frédérique ^c   Brossard, Cédric ^a   Gary Gouy, Hélène ^a   Bismuth, Georges ^a,d  

^a CNRS   (France)

^b BICHAT HOSPITAL   (France)

^c INSTITUT PASTEUR   (France)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PROLINE; PROTEIN TYROSINE KINASE; RNA BINDING PROTEIN; TYROSINE;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYBRIDOMA; LEUKEMIA CELL LINE; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; CELL MEMBRANE; CELL NUCLEUS; DNA-BINDING PROTEINS; HUMANS; HYBRIDOMAS; INTRACELLULAR FLUID; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MICE; NUCLEAR LOCALIZATION SIGNALS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FYN; RNA-BINDING PROTEINS; SRC-FAMILY KINASES; T-LYMPHOCYTES; TYROSINE;

EID: 0033564327     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Wong, G., O. Müller, R. Clark, L. Conroy, M. F. Moran, P. Polakis, and F. McCormick. 1992. Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62. Cell 69:551.
2. McBride, A. E., A. Schlegel, and K. Kirkegaard. 1996. Human protein Sam68 relocalization and interaction with poliovirus RNA polymerase in infected cells. Proc. Natl. Acad. Sci. USA 93:2296.
3. Ishidate, T., S. Yoshihara, Y. Kawasaki, B. C. Roy, K. Toyoshima, and T. Akiyama. 1997. Identification of a novel nuclear localization signal in Sam68. FEBS Lett. 409:237.
4. McBride, A. E., S. J. Taylor, D. Shalloway, and K. Kirkegaard. 1998. KH domain integrity is required for wild-type localization of Sam68. Exp. Cell Res. 241:84.
5. Siomi, H., M. J. Matunis, W. M. Michael, and G. Dreyfuss. 1993. The pre-mRNA binding K protein contains a novel evolutionarily conserved motif. Nucleic Acids Res. 21:1193.
6. Chen, T., B. B. Damaj, C. Herrera, P. Lasko, and S. Richard. 1997. Self-association of the single-KH-domain family members Sam68, GRP33, GLD-1, and Qk1: role of the KH domain. Mol. Cell. Biol. 17:5707.
7. Taylor, S. J., and D. Shalloway. 1994. An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis. Nature 368:867.
8. Lin, Q., S. J. Taylor, and D. Shalloway. 1997. Specificity and determinants of sam68 RNA binding: implications for the biological function of k homology domains. J. Biol. Chem. 272:27274.
9. Barlat, I., F. Maurier, M. Duchesne, E. Guitard, B. Tocque, and F. Schweighoffer. 1997. A role for Sam68 in cell cycle progression antagonized by a spliced variant within the KH domain. J. Biol. Chem. 272:3129.
10. Fumagalli, S., N. F. Totty, J. J. Hsuan, and S. A. Courtneidge. 1994. A target for Src in mitosis. Nature 368:871.
11. Richard, S., D. Yu, K. J. Blumer, D. Hausladen, M. W. Olszowy, P. A. Connelly, and A. S. Shaw. 1995. Association of p62, a multifunctional SH2- and SH3-domain binding protein, with src family tyrosine kinases, Grb2, and phospholipase Cγ-1. Mol. Cell. Biol. 15:186.
12. Finan, P. M., A. Hall, and S. Kellie. 1996. Sam68 from an immortalized B-cell line associates with a subset of SH3 domains. FEBS Lett. 389:141.
13. Bunnell, S. C., P. A. Henry, R. Kolluri, T. Kirchhausen, R. J. Rickles, and L. J. Berg. 1996. Identification of Itk/Tsk Src homology 3 domain ligands. J. Biol. Chem. 271:25646.
14. Trüb, T., J. D. Frantz, M. Miyazaki, H. Band, and S. E. Shoelson. 1997. The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signaling. J. Biol. Chem. 272:894.
15. Jabado, N., A. Pallier, F. Le Deist, F. Bernard, A. Fischer, and C. Hivroz. 1997. CD4 ligands inhibit the formation of multifunctional transduction complexes involved in T cell activation. J. Immunol. 158:94.
16. Fusaki, N., A. Iwamatsu, M. Iwashima, and J. Fujisawa. 1997. Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling. J. Biol. Chem. 272:6214.
17. Lawe, D. C., C. Hahn, and A. J. Wong. 1997. The Nck SH2/SH3 adaptor protein is present in the nucleus and associates with the nuclear protein SAM68. Oncogene 14:223.
18. Guinamard, R., M. Fougereau, and P. Seckinger. 1997. The SH3 domain of Bruton's tyrosine kinase interacts with Vav, Sam68 and EWS. Scand. J. Immunol. 45:587.
19. Guitard, E., I. Barlat, F. Maurier, F. Schweighoffer, and B. Tocque. 1998. Sam68 is a Ras-GAP-associated protein in mitosis. Biochem. Biophys. Res. Commun. 245:562.
20. + T cells is dependent on CD4 molecule expression. J. Immunol. 161:2798.
21. Wang, L. L., S. Richard, and A. S. Shaw. 1995. p62 association with RNA is regulated by tyrosine phosphorylation. J. Biol. Chem. 270:2010.
22. Lang, V., D. Mege, M. Semichon, H. Gary-Gouy, and G. Bismuth. 1997. A dual participation of ZAP-70 and scr protein tyrosine kinases is required for TCR-induced tyrosine phosphorylation of Sam68 in Jurkat T cells. Eur. J. Immunol. 27:3360.
23. lck is an early event in interleukin-2-induced onset of cell cycle progression in T-lymphocytes. J. Biol. Chem. 270:2506.
24. Blank, U., B. Boitel, D. Mege, M. Ermonval, and O. Acuto. 1993. Analysis of tetanus toxin peptide/DR recognition by human T cell receptors reconstituted into a murine T cell hybridoma. Eur. J. Immunol. 23:3057.
25. Clipstone, N. A., and G. R. Crabtree. 1992. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature 357:695.
26. Takebe, Y., M. Seiki, J. Fujisawa, P. Hoy, K. Yokota, K. Arai, M. Yoshida, and N. Arai. 1988. SR α promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Mol. Cell. Biol. 8:466.
27. fyn-mediated signal transduction on T cell activation. Int. Immunol. 6:1245.
28. fyn mediates interaction with glycosyl-phosphatidylinositol-anchored proteins. Mol. Cell. Biol. 13:6385.
29. fyn affects subcellular localization. J. Biol. Chem. 269:16701.
30. Shenoy-Scaria, A. M., D. J. Dietzen, J. Kwong, D. C. Link, and D. M. Lublin. 1994. Cysteine 3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae. J. Cell Biol. 126:353.
31. fyn is reversible and sufficient for plasma membrane association. Mol. Cell. Biol. 8:1159.
32. fyn src homology 4 domain define a motif for immune-receptor tyrosine-based activation motif (ITAM) binding and for plasma membrane localization. J. Cell Biol. 133:1007.
33. Pillay, I., H. Nakano, and S. V. Sharma. 1996. Radicicol inhibits tyrosine phosphorylation of the mitotic Src substrate Sam68 and retards subsequent exit from mitosis of Src-transformed cells. Cell Growth Differ. 7:1487.
34. Laird, A. D., and D. Shalloway. 1997. Oncoprotein signalling and mitosis. Cell. Signal. 9:249.
35. Weng, Z., S. M. Thomas, R. J. Rickles, J. A. Taylor, A. W. Brauer, C. Seidel-Dugan, W. M. Michael, G. Dreyfuss, and J. S. Brugge. 1994. Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains. Mol. Cell. Biol. 14:4509.
36. Ley, S. C., M. Marsh, C. R. Bebbington, K. Proudfoot, and P. Jordan. 1994. Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes. J. Cell Biol. 125:639.
37. Xavier, R., T. Brennan, Q. Li, C. McCormack, and B. Seed. 1998. Membrane compartmentation is required for efficient T cell activation. Immunity 8:723.
38. Stefanova, I., V. Horejsi, I. J. Ansotegui, W. Knapp, and H. Stockinger. 1991. GPI-anchored cell-surface molecules complexed to protein tyrosine kinases. Science 254:1016.
39. fyn protein tyrosine kinase in T cells. J. Biol. Chem. 267:12317.
40. Hiroaki, H., W. Klaus, and H. Senn. 1996. Determination of the solution structure of the SH3 domain of human p56 Lck tyrosine kinase. J. Biomol. NMR 8:105.
41. Qian, D., S. Lev, N. S. van Oers, I. Dikic, J. Schlessinger, and A. Weiss. 1997. Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling. J. Exp. Med. 185:1253.
42. fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif. Mol. Cell. Biol. 14:3729.
43. fyn tyrosine kinase associates with multiple T-cell receptor subunits through its unique amino-terminal domain. Mol. Cell. Biol. 12:5438.
44. fyn and ZAP-70, in T cell signaling. J. Immunol. 156:1369.
45. Vernet, C., and K. Artzt. 1997. STAR, a gene family involved in signal transduction and activation of RNA. Trends Genet. 13:479.
46. Arning, S., P. Gruter, G. Bilbe, and A. Kramer. 1996. Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA. RNA 2:794.
47. Ebersole, T. A., Q. Chen, M. J. Justice, and K. Artzt. 1996. The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins. Nat. Genet. 12:260.
48. Jones, A. R., and T. Schedl. 1995. Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affect a conserved domain also found in Src-associated protein Sam68. Genes Dev. 9:1491.
49. Zorn, A M., and P. A. Krieg. 1997. The KH domain protein encoded by quaking functions as a dimer and is essential for notochord development in Xenopus embryos. Genes Dev. 11:2176.
50. Sidman, R. L., M. M. Dickie, and S. H. Appel. 1964. Mutant mice (quaking and jimpy) with deficient myelination in the central nervous system. Science 144:309.
51. Resh, M. D. 1994. Myristylation and palmitylation of Src family members: the fats of the matter. Cell 76:411.
52. Jans, D. A., and S. Hubner. 1996. Regulation of protein transport to the nucleus: central role of phosphorylation. Physiol. Rev. 76:651.