Regulated degradation of an endoplasmic reticulum membrane protein in a tubular lysosome in Leishmania mexicana

Molecular Biology of the Cell

Volumn 12, Issue 8, 2001, Pages 2364-2377

  Mullin, K A ^a   Foth, B J ^a   Ilgoutz, S C ^a   Callaghan, J M ^a   Zawadzki, J L ^a   McFadden, G I ^a   McConville, M J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLPHOSPHATIDYLINOSITOL; GREEN FLUORESCENT PROTEIN; MEMBRANE PROTEIN;

ARTICLE; CELL FRACTIONATION; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; LEISHMANIA MEXICANA; LEISHMANIASIS; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 0035168055     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.12.8.2364     Document Type: Article

References (43)

1. Molecular cloning and cellular localization of a BIP homologue in Trypanosoma brucei - Divergent ER retention signals in a lower eukaryote
2. Expression of lipophosphoglycan, high molecular weight phosphoglycan and glycoprotein gp63 in promastigotes and amastigotes of Leishmania mexicana
3. Ubiquitin and control of protein fate in the secretory and endocytic pathways
4. Phase separation of integral membrane proteins in Triton X-114 solution
5. Low temperature reversibly inhibits transport from tubular endosomes to a perinuclear, acidic compartment in African trypanosomes
6. The fine structure of Crithidia fasciculata with special reference to the organelles involved in the ingestion and digestion of protein
7. Processing, and trafficking of cysteine proteases in Leishmania mexicana
8. 2+ storage compartment in trypanosmatids and apicomplexan parasites
9. The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness
10. Membrane transport in the endocytic pathway
11. The cytoskeleton of trypanosomatid parasites
12. Degradation of stearoylcoenzyme A desaturase: Endoproteolytic cleavage by an integral membrane protease
13. The kinetics of mannose 6-phosphate receptor trafficking in the endocytic pathway in Hep-2 cells: The receptor enters and rapidly leaves multivesicular endosomes without accumulating in the prelysosomal compartment
14. Lipophosphoglycan is not required for infection of macrophages or mice by Leishmania mexicana
15. Proteophosphoglycan from Leishmania promastigotes and amastigotes
16. Glycosyl-phosphatidylinositol biosynthetic enzymes are localized to a stable tubular subcompartment of the endoplasmic reticulum in Leishmania mexicana
17. Evidence that free GPI glycolipids are essential for growth of Leishmania mexicana
18. Processing and transport of a lysosomal membrane glycoprotein is developmentally regulated in African trypanosomes
19. A lipid associated with the antiphospholipid syndrome regulates endosome structure and function
20. A conditionally lethal yeast mutant blocked in the first steping lycosyl phosphatidylinositol anchor synthesis
21. Developmental changes in the glycosylated phosphatidylinositols of Leishmania donovani. Characterization of the promastigote and amastigote glycolipids
22. The structure, biosynthesis and function of glycosylated phosphatidylinositol in the parasitic protozoa and higher eukaryotes
23. Recent developments in the cell biology and biochemistry of glycosylphosphatidylinositol lipids
24. Designing glycoconjugate biosynthesis for an insidious intent: Phosphoglycan assembly in Leishmania parasites
25. Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions
26. Characterization of a novel late endosome/lysosomal compartment in Leishmania mexicana
27. Critical roles of glycosyl-phosphatidyl inositol for Trypanosoma brucei
28. Developmental abnormalities of glycosylphos-phatidylinositol-anchor-deficient embryos revealed by Cre/loxP system
29. Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body
30. Endocytosis and secretion in trypanosomatid parasites -tumultuous traffic in a pocket
31. Comparative fine structure and surface glycosonjugate expression of three stages of Leishmania major
32. Delineation of three pathways of glycosylphosphatidyl-inositol biosynthesis in Leishmania mexicana - Precursors from different pathways are assembled on distinct pools of phosphatidylinositol and undergo fatty acid remodeling
33. Proteases of protozoan parasites
34. The role of phosphoglycans in Leishmania-sand fly interactions
35. Expression, and characterization of a recombinant cysteine proteinase of Leishmania mexicana
36. Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major
37. Biosynthesis of glycosylphosphatidylinositols in mammals and unicellular microbes
38. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
39. How glycosylphosphatidylinositol-anchored membrane proteins are made
40. A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast
41. Gene cloning and cellular localization of a membrane-bound acid phosphatase of Leishmania mexicana
42. Distribution of GPI-anchored proteins in the protozoan parasite Leishmania, based on an improved ultrastructural description using high-pressure frozen cells
43. Surface antigens of Leishmania mexicana amastigotes - Characterization of glycoinositol phospholipids and a macrophage-derived glycosphingolipid