Quinolinic acid lesion of the nigrostriatal pathway: Effect on turning behaviour and protection by elevation of endogenous kynurenic acid in rattus norvegicus

Neuroscience Letters

Volumn 262, Issue 2, 1999, Pages 81-84

  Miranda, A F ^a   Sutton, M A ^a   Beninger, R J ^a   Jhamandas, K ^a   Boegman, R J ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Excitotoxicity; Kynurenic acid; Parkinson's disease; Quinolinic acid; Substantia nigra; Turning behaviour

Indexed keywords

DOPAMINE; EXCITATORY AMINO ACID; EXCITOTOXIN; KYNURENIC ACID; KYNURENINASE; KYNURENINE; KYNURENINE 3 MONOOXYGENASE; PROBENECID; QUINOLINIC ACID;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOPAMINERGIC NERVE CELL; MALE; NERVE CELL DEGENERATION; NEUROPROTECTION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

ALANINE; ANIMALS; CORPUS STRIATUM; EXCITATORY AMINO ACID ANTAGONISTS; HYDROLASES; KYNURENIC ACID; KYNURENINE; KYNURENINE 3-MONOOXYGENASE; MALE; MIXED FUNCTION OXYGENASES; MOTOR ACTIVITY; NEURONS; NEUROPROTECTIVE AGENTS; NIACIN; PARKINSON DISEASE, SECONDARY; PROBENECID; QUINOLINIC ACID; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE; UP-REGULATION;

EID: 0033525791     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00036-1     Document Type: Article

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