Targeting of a tail-anchored protein to endoplasmic reticulum and outer membrane by independent but competing pathways

Molecular Biology of the Cell

Volumn 12, Issue 8, 2001, Pages 2482-2496

  Borgese, N ^a   Gazzoni, I ^a   Barberi, M ^a   Colombo, S ^a   Pedrazzini, E ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME B5; GREEN FLUORESCENT PROTEIN; OUTER MEMBRANE PROTEIN; THREONINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FRACTIONATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HELA CELL; HUMAN; HUMAN CELL; MAMMAL; MICROSOME; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; PROTEIN TARGETING; TRANSLATION REGULATION;

EID: 0035159675     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.12.8.2482     Document Type: Article

References (41)

1. Genetic control of antibody response to bovine rhodopsin in mice: Epitope mapping of rhodopsin structure
2. Multiple subcellular localization of bcl-2: Detection in nuclear outer membrane, endoplasmic reticulum, and mitochondrial membrane
3. A guide to the use of pore-forming toxins for controlled permeabilization of cell membranes
4. 5 reductase requires myristic acid for association with outer mitochondrial but not endoplasmic reticulum membranes
5. 5 - The problem of postranslational targeting to the endoplasmic reticulum
6. 5 reductase in rat liver cells, studied with a quantitative radioimmunoblotting assay
7. A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin
8. Expression of the wild-type and mutated vacuolar storage protein phaseolin in Xenopus oocytes reveals relationships between assembly and intracellular transport
9. Identification of a glycoprotein from rat liver mitochondrial inner membrane and demonstration of its origin in the endoplasmic reticulum
10. 5 suggests novel targeting pathways
11. 5 is contained within the carboxyl-terminal region
12. 5 to phospholipid vesicles and biological membranes. Effect of orientation on intermembrane transfer and digestion by carboxypeptidase Y
13. Import of protein into mitochondria and chloroplasts
14. Retention of cytochrome b(5) in the endoplasmic reticulum is transmembrane and luminal domain-dependent
15. A splce-isoform of vesicle-associated membrane protein-1 (VAMP-1) contains a mitochondrial targeting
16. Assembly of Bcl-2 into microsomal and outer mitochondrial membranes
17. Characterization of the signal that directs Tom20 to the mitochondrial outer membrane
18. Biogenesis of porin of the outer mitochondrial membrane involves an import pathway via receptors and the general import pore of the TOM complex
19. Charged aminoacids at the carboxyl-terminal portions determine the intracellular location of two isoforms of cytochrome b(5)
20. In situ topology of cytochrome b(5) in the endoplasmic reticulum membrane
21. Transport route for synaptobrevin via a novel pathway of insertion into the endoplasmic reticulum membrane
22. A class of membrane proteins with C-terminal anchor
23. Targeting and insertion of C-terminally anchored proteins to the mitochondrial outer membrane is specific and saturable but does not strictly require ATP or molecular chaperones
24. 5 in a single cell
25. Membrane topology and retention of microsomal aldehyde dehydrogenase in the endoplasmic reticulum
26. Signal anchor sequence insertion into the outer mitochondrial membrane. Comparison with porin and the matrix protein targeting pathway
27. 5 are necessary for its targeting to the endoplasmic reticulum
28. Recruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein
29. Protein import into mitochondria
30. Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence
31. Mechanism of residence of cytochrome b(5), a tail-anchored protein, in the endoplasmic reticulum
32. Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses
33. Common principles of protein translocation across membranes
34. Direct membrane insertion of voltage-dependent anion-selective channel protein catalyzed by mitochondrial Tom20
35. A mitochondrial membrane protein is required for translocation of phosphatidylserine from mitochondria-associated membranes to mitochondria
36. Enzymatic deglycosylation of asparagine-linked glycans: Purification, properties, and specificities of oligosaccharide-cleaving enzymes from Flavobacterium menigosepticum
37. Abnormalities in mitochondria-associated membranes and phospholipid biosynthetic enzymes in the mnd/mnd mouse model of neuronal ceroid lipofuscinosis
38. The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol
39. Reconstitution of translocation-competent membrane vesicles from detergent-solubilized dog pancreas rough microsomes