Progesterone-mediated stimulation of osteoprogenitor proliferation and differentiation in cell populations derived from adult or fetal rat bone tissue depends on the serum component of the culture media

Osteoporosis International

Volumn 7, Issue 4, 1997, Pages 323-330

  Ishida, Y ^a   Bellows, C G ^a   Tertinegg, I ^a   Heersche, J N M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Aging; Dexamethasone; Osteoblasts; Osteoprogenitors; Progesterone; Serum dependent effect

Indexed keywords

DEXAMETHASONE; PROGESTERONE;

ANIMAL CELL; ARTICLE; CALVARIA; CELL CULTURE; CELL DIFFERENTIATION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; DOSE RESPONSE; FETUS; FETUS CELL; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; RAT; STEM CELL; VERTEBRA;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; CULTURE MEDIA; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; FETUS; LUMBAR VERTEBRAE; OSTEOBLASTS; PROGESTERONE; RATS; RATS, WISTAR; SERUM ALBUMIN, BOVINE; SKULL;

EID: 0030795880     PISSN: 0937941X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01623772     Document Type: Article

References (38)

1. Albright F, Smith PH, Richardson AM. Post-menopausal osteoporosis: its clinical features. JAMA 1941;116:2465-74.
2. Slemenda S. Hui SL, Longcope C, Johnston CC. Sex steroids and bone mass: a study of changes about the time of menopause. J Clin Invest 1987,80:1261-9.
3. Riggs BL, Jowesy J, Goldsmith RS, Kelly PJ, Hoffman DL, Arnauld CD. Short and long term effects of estrogen and synthetic anabolic hormones in postmenopausal osteoporosis. J Clin Invest 1972;52:1659-63.
4. Lindsay R, Aitken JM, Anderson JB, Hart DM, MacDonald ER, Clark AC. Longterm prevention of postmenopausal osteoporosis by estrogen: evidence for an increased bone mass after delayed onset of estrogen treatment. Lancet 1976;1:1038-410.
5. Gallagher JC, Kable WT, Goldgar D. Effect of progestin therapy on cortical and trabecular bone: comparison with estrogen. Am J Med 1991;90:171-8.
6. Prior JC, Vigna YM, Scheschter MT, Burgess AE. Spinal bone loss and ovulatory disturbances. N Engl J Med 1990;323:1221-7.
7. Scheven BAA, Daman CA, Hamilton NJ, Verhaar HJJ, Duursma SA. Stimulatory effects of estrogen and progesterone on proliferation and differentiation of normal human osteoblastlike cells in vitro. Biochem Biophys Res Commun 1992:186:54-60.
8. Tremollieres FA, Strong DD, Baylink DJ, Mohan S. Progesterone and promegesterone stimulate human bone cell proliferation and insulin-like growth factor-2 production. Acta Endocrinol (Copenh) 1992;126:329-37.
9. Wei LL, Leach MW, Miner RS, Demers LM. Evidence for progesterone receptors in human osteoblast-like cells. Biochem Biophys Res Commun 1993;195:525-32.
10. Grigoriadis AE, Heersche JNM, Aubin JE. Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone derived clonal cell population. J Cell Biol 1988;106:2139-51.
11. Maenpaa P, Mahonen A, Pirskanen A. Hormonal regulation of vitamin D receptor levels and osteocalcin synthesis in human osteosarcoma cells. Calcif Tissue Int 1991;49(Suppl):S85-6.
12. Canalis E, Ratsz LG. Effect of sex steroids on bone collagen synthesis in vitro. Calcif Tissue Int 1978:25-105-10.
13. Orwoll ES, Stribrska L, Ramsey EE, Keenan EJ. Androgen receptors in osteoblast-like cell lines. Calcif Tissue Int 1991;49:183-7.
14. Schwartz Z, Soskolne WA, Neubauer T, Goldstein M, Adi S, Omoy A. Direct and sex-specific enhancement of bone formation and calcification by sex steroids in fetal mice long bone in vitro: biochemical and morphometric study. Endocrinology 1991;129:1167-74.
15. Heersche JNM, Reimers S, Denkovski P, Bellows CG. Aubin JE. Heterogeneity of osteoblasts in vivo and in vitro. In: Chnstiansen C, Riis B, editors. Fourth international symposium on osteoporosis. Rodovre, Denmark: Osteopress, 1993:225-7.
16. Clover J, Gowen. Are MG-63 and HOS TE85 human osteosarcoma cell lines representative models of osteoblastic phenotype? Bone 1994;15:585-91.
17. Ishida Y, Tertinegg I, Heersche JNM. Progresterone and dexamethasone stimulate proliferation and differentiation of osteoprogenitors and progenitors for adipocytes and macrophages in cell populations derived from adult rat vertebrae. J Bone Miner Res 1996;11:921-30.
18. Gray TK, Flynn TC, Gray KM, Nabell LM. 17β-Estradiol acts directh on the clonal osteoblastic cell line UMR 106. Proc Natl Acad Sci USA 1987;84:6267-71.
19. Bellows CG, Aubin JE, Heersche JNM, Antosz ME. Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations. Calcif Tissue Int 1986;38:143-54.
20. Bellows CG, Aubin JE, Heersche JNM. Physiological concentrations of glucocorticoids stimulate formation of bone nodules from isolated rat calvaria cells in vitro. Endicronology 1987;121:1985-92.
21. Bellows CG, Aubin JE, Heersche JNM. Initiation and progression of mineralization of bone nodules formed in vitro: the role of alkaline phosphatase and organic phosphate. Bone Miner 1991;14:27-40.
22. 1-response in a selected population of bone cells after repeated subculture and storage at -80 °C. Endocrinology 1977;100:1233-41.
23. Eriksen EF, Colvard DS, Berg NL, et al. Evidence of estrogenreceptors in normal human osteoblast-like cells. Science 1988;241:81-4.
24. Komm BS, Terpening CM, Benz DJ, et al. Estrogen binding receptor mRNA. and biological response in osteoblast-like osteosarcoma cells. Science 1988;241:81-4.
25. Colvard DS, Eriksen EF, Keeting PE, et al. Identification of androgen receptors in normal human osteoblast like cells. Proc Natl Acad Sci USA 1989;86:854-7.
26. Miles B, Fuchs-Young R. Development of a non-radioactive quantitative PCR technique used to detect progesterone receptor levels in bone [abstract]. J Bone Min Res 1995;10:S333.
27. Ishida Y, Heersche JNM. Estrogen enhances progesteroneinduced proliferation and differentiation of osteoprogenitors in bone cell populations derived from lumbar vertebrae of female adult rats [abstract]. J Bone Miner Res 1996;11:8431.
28. Samuels H, Stanley H, Cassanova J. Depletion of L-3,5-triiodotbyronine and L-thyroxine in euthyroid calf serum for use in cell culture studies of action of thyroid hormone. Endocrinology 1979;105:80-5.
29. 3) and dexamethasone interact to modulate osteoprogenitor cell differentiation in fetal rat calvaria cell cultures. Bone 1995;16:545-9.
30. Ohishi K, Nishikawa S, Nagata T, et al. Physiological concentrations of retinoic acid suppress the osteoblastic differentiation of fetal rat calvaria cells in vitro. Eur J Endocrinol 1995;133:335-41.
31. Corvol M-T, Carrascosa A, Tsagris L, Blanchard O, Rappaport R. Evidence for a direct in vitro action of sex steroids on rabbit cartilage cells during skeletal growth: influence of age and sex. Endocrinology 1989;120:1422-9.
32. Phillips LS, Herington AC, Daughaday W. Steroid hormone effects on somatomedin. I. Somatomedin action in vitro. Endocrinology 1975;75:780-6.
33. Roholl PJM, Blauw E, Zurcher C, Dormans JAMA, Theuns HM. Evidence for diminished maturation of preosteoblasts into osteoblasts during aging in rats: an ultrastructural analysis. J Bone Miner Res 1994; J Bone Miner Res 1994;9:355-66.
34. Roholl PJM, Blauw E, Zurcher C, Dormans JAMA, Theuns HM. Evidence for diminished maturation of preosteoblasts into osteoblasts during aging in rats: an ultrastructural analysis. J Bone Miner Res 1994; J Bone Miner Res 1994;9:355-66.
35. Pfeilschifter J, Diel I, Pilz U, et al. Mitogenic responsiveness of human bone cells in vitro to hormones and growth factors decreases with age. J Bone Miner Res 1993;8:707-17.
36. Ishida Y, Heersche JNM. Progesterone stimulates proliferation and differentiation of osteoprogenitor cells in bone cell populations derived from adult female but not from adult male rats. Bone 1997;20:17-25.
37. Maniatopoulos C, Sodek J, Melcher AH. Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell Tissue Res 1988;254:317-30.
38. Turksen K, Aubin JE. Positive and negative immunoselection for enrichment of two classes of osteoprogenitor cells. J Cell Biol 1991:114:373-84.