Expression of the developmental markers STRO-1 and alkaline phosphatase in cultures of human marrow stromal cells: Regulation by fibroblast growth factor (FGF)-2 and relationship to the expression of FGF receptors 1-4

Bone

Volumn 27, Issue 2, 2000, Pages 185-195

  Walsh, S ^a   Jefferiss, C ^a   Stewart, K ^a   Jordan, G R ^b   Screen, J ^c   Beresford, J N ^a  

^a UNIVERSITY OF BATH   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

^c HOLLAND LABORATORY   (United States)

Author keywords

Alkaline phosphatase; Dexamethasone (Dx); Fibroblast growth factor 2 (FGF 2); Human; Osteoblasts; STRO 1

Indexed keywords

ALKALINE PHOSPHATASE; ASCORBIC ACID; DEXAMETHASONE; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN M; RECOMBINANT FIBROBLAST GROWTH FACTOR;

ARTICLE; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; CULTURE MEDIUM; DOSE RESPONSE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NORMAL HUMAN; PROTEIN EXPRESSION; STROMA CELL;

ADULT; AGED; ALKALINE PHOSPHATASE; ANTIBODIES, MONOCLONAL; BIOLOGICAL MARKERS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; DEXAMETHASONE; FEMALE; FIBROBLAST GROWTH FACTOR 2; FLOW CYTOMETRY; GLUCOCORTICOIDS; HUMANS; HYBRIDOMAS; MALE; MIDDLE AGED; OSTEOBLASTS; PROTEIN-TYROSINE KINASES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 4; RECEPTORS, FIBROBLAST GROWTH FACTOR; STROMAL CELLS;

EID: 0033941226     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(00)00319-7     Document Type: Article

References (49)

1. Anderson J., Burns H.D., Enriquez Harris P., Wilkie A.O.M., Heath J.K. Apert syndrome mutations in fibroblast growth factor receptor-2 exhibit increased affinity for FGF ligand. Hum Mol Genet. 7:1998;1475-1483.
2. Aubin J.E., Turksen K. Monoclonal antibodies as tools for studying the osteoblast lineage. Microsc Res Technol. 33:1996;128-140.
3. Baron J., Klein O.K., Yanovski J.A., Novosad J.A., Bacher J.D., Bolander M.E., Cutler G.B. Induction of growth plate ossification by basic fibroblast growth factor. Endocrinology. 135:1994;2790-2793.
4. 3 on osteogenic differentiation of human marrow stromal cells in vitro. Arch Oral Biol. 39:1994;941-947.
5. Berrada S., Lefebvre F., Harmand M.F. The effect of recombinant human basic fibroblast growth-factor (rhFGF-2) on human osteoblast in growth and phenotype expression. In Vitro Cell Dev Biol. 31:1995;698-702.
6. Boden S.D. Bioactive factors for bone tissue engineering. Clin Orthop Rel Res. 367:(Suppl.):1999;S84-S94.
7. Bruder S.P., Fink D.J., Caplan A.I. Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy. J Cell Biochem. 56:1994;283-294.
8. Canalis E., Centrella M., McCarthy T. Effects of basic fibroblast growth factor on bone formation in vitro. J Clin Invest. 81:1988;1572-1577.
9. Cheng S.-L., Yang J.W., Rifas L., Zhang S.-F., Avioli L.V. Differentiation of human bone marrow osteogenic stromal cells in vitro Induction of the osteoblast phenotype by dexamethasone . Endocrinology. 134:1994;277-286.
10. Coffin J.D., Florkiewicz R.Z., Nenmann J., Mort-Hopkins T., Dorn G.W., Lightfoot P., German R., Howles P.N., Kier A., O'Toole B.A. Abnormal bone growth and selective translational regulation in basic fibroblast growth factor (FGF-2) in transgenic mice. Mol Biol Cell. 6:1995;1861-1873.
11. Debiais F., Hott M., Graulet A.M., Marie P.J. The effects of fibroblast growth factor-2 on human neonatal calvaria osteoblastic cells are differentiation stage specific. J Bone Miner Res. 13:1998;645-653.
12. Gallagher J.A., Gundle R., Beresford J.N. Isolation and culture of bone-forming cells (osteoblasts) from human bone. Jones G.E. Methods in Molecular Medicine Human Cell Culture Protocols . 1996;233-262 Humana, Totowa, NJ.
13. Gibbons A.J., Walsh S., Beresford J.N. PDGF influences colony forming efficiency and proliferation, but not the expression of alkaline phosphatase in cultures of human marrow stromal cells. Bone. 17:1995;557-596. [abstract].
14. Globus R.K., Ploulet J., Gospodarowicz D. Cultured bovine bone cells synthesise basic fibroblast growth factor and store it in their extra-cellular matrix. Endocrinology. 124:1989;1539-1547.
15. Green P.J., Walsh F.S., Doherty P. Promiscuity of fibroblast growth factor receptors. Bioessays. 18:1997;639-646.
16. + fraction of adult human bone marrow contains the osteogenic precursors. Blood. 84:1994;4164-4173.
17. Gronthos S., Simmons P.J. The growth factor requirements of STRO-1 positive human bone marrow stromal precursors under serum-deprived conditions in vitro. Blood. 85:1995;929-940.
18. Gronthos S., Zannettino A.C.W., Graves S.E., Ohta S., Hay S.J., Simmons P.J. Differential cell surface expression of the STRO-1 and alkaline phosphatase antigens on discrete developmental stages in primary cultures of human bone cells. J Bone Miner Res. 14:1999;47-56.
19. Gundle R., Beresford J.N. The isolation and culture of cells from explants of human trabecular bone. Calcif Tissue Int. 56:(Suppl. 1):1995;S8-S10.
20. Gundle R., Joyner C.J., Triffit J.T. Human bone tissue formation in diffusion chamber culture in vivo by bone-derived cells and marrow stromal cells. Bone. 16:1997;597-601.
21. Horwitz E.M., Prockup D.J., Fitzpatrick L.A., Koo W.W.K., Gordon P.L., Neel M., Sussman M., Orchard P., Marx J.C., Pyeritz R.E., Brenner M.K. Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nature Med. 5:1999;309-313.
22. Iseki S., Wilkie A.O.M., Heath J.K., Ishimaru T., Eto K., Morriss-Kay G.M. FGFR 2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2. Development. 124:1997;3375-3384.
23. Ishida Y., Heersche J.N.M. Glucocorticoid-induced osteoporosis Both in vivo and in vitro concentrations of glucocorticoids higher than physiological levels attenuate osteoblast differentiation . J Bone Miner Res. 13:1998;1822-1826.
24. Johnstone B., Yoo J.U. Autologous mesenchymal progenitor cells in articular cartilage repair. Clin Orthop Related Res. 367:(Suppl.):1999;S156-S162.
25. Kato T., Kawaguchi H., Hanada K., Aoyama I., Hiyama Y., Nakamura T., Kuzutani K., Tamura M., Kurokawa T., Nakamura K. Single local injection of recombinant fibroblast growth factor-2 stimulates healing of segmental bone defects in rabbits. J Orthop Res. 16:1998;654-659.
26. Martin G.R. The roles of FGFs in the early development of vertebrate limbs. Genes Devel. 12:1998;1571-1586.
27. Martin I., Muraglia A., Campanile G., Cancedda R., Quarto R. Fibroblast growth factor-2 supports ex vivo expansion and maintenance of osteogenic precursors from human bone marrow. Endocrinology. 138:1997;4456-4462.
28. Molteni A., Modrowski D., Hott M., Marie P.J. Differential expression of fibroblast growth factor receptor-1, -2, and -3 and syndecan-1, -2, and -4 in neonatal rat mandibular condyle and calvaria during osteogenic differentiation in vitro. Bone. 24:1999;337-347.
29. Molteni A., Modrowski D., Hott M., Marie P.J. Alterations of matrix- and cell-associated proteoglycans inhibit osteogenesis and growth response to fibroblast growth factor-2 in cultured rat mandibular condyle and calvaria. Cell Tissue Res. 285:1999;523-536.
30. Muraglia A., Martin I., Cancedda R., Quarto R. A nude mouse model for human bone formation in unloaded conditions. Bone. 22:(Suppl.):1998;131S-134S.
31. Nagai H., Tsukuda R., Mayahara H. Effects of basic fibroblast growth factor (bFGF) on bone formation in growing rats. Bone. 16:1995;367-373.
32. Nakamura T., Hara Y., Tagawa M., Tamura M., Yuge T., Fukada H., Nigi H. Recombinant human basic fibroblast growth factor accelerates fracture healing by enhancing callus remodelling in experimental dog tibial fracture. J Bone Miner Res. 13:1998;942-949.
33. Nevo Z., Robinson Z., Horowitz S., Hasharoni A., Yayon A. The manipulated mesenchymal stem cells in regenerated skeletal tissues. Cell Transplant. 7:1998;63-70.
34. Oliver L.J., Rifkin D.B., Gabrilove J., Hanncocks M.-J., Wilson E.L. Long-term culture of human bone marrow stromal cells in the presence of basic fibroblast growth factor. Growth Factors. 3:1990;231-236.
35. Onyia J.E., Clapp D.W., Long H., Hock J.M. Osteoprogenitor cells as targets for ex vivo gene transfer. J Bone Miner Res. 13:1998;20-30.
36. Owen M.E., Friedenstein A.J. Stromal stem cells Marrow-derived osteogenic precursors . Cell and Molecular Biology of Vertebrate Hard Tissues. Ciba Foundation Symposium 136. 1988;42-60 Wiley, Chichester, UK.
37. Phinney D.G., Kopen G., Isaacson R.L., Prockup D.J. Plastic adherent stromal cells from bone marrow of commonly used strains of inbred mice Variations in yield, growth, and differentiation . J Cell Biochem. 72:1999;570-585.
38. Pitaru S., Kotev-Emeth S., Noff D., Kaffular S., Savion N. Effect of basic fibroblast growth factor on the growth and differentiation of adult stromal bone marrow cells Enhanced development of mineralised bone-like tissue in culture . J Bone Miner Res. 8:1993;919-929.
39. Pri-Chen S., Pitaru S., Lokiec F., Savion N. Basic fibroblast growth factor enhances the growth and expression of the osteogenic phenotype of dexamethasone-treated human bone marrow-derived bone-like cells in culture. Bone. 23:1998;111-117.
40. Rifas, L., McDermott, M. J., Zhang, S.-F., Oliver, C., Avioli, L. V., and Cheng, S.-L. Basic fibroblast growth factor inhibits growth and differentiation of human bone marrow osteoprogenitor cells [abstract]. J Bone Miner Res 10(Suppl. 1):S411; 1995.
41. Scutt A., Bertram P. Basic fibroblast growth factor in the presence of dexamethasone stimulates colony formation, expansion, and osteoblastic differentiation by rat bone marrow stromal cells. Calcif Tissue Int. 64:1999;69-77.
42. Simmons P.J., Torok-Storb B. Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood. 78:1991;55-62.
43. Stewart K., Walsh S., Screen J., Jefferiss C.M., Chainey J., Jordan G.R., Beresford J.N. Further characterisation of cells expressing STRO-1 in cultures of adult human bone marrow stromal cells. J Bone Miner Res. 14:1999;1345-1356.
44. Wang J.-K., Gao G., Goldfarb M. Fibroblast growth factor receptors have different signalling and mitogenic potentials. Mol Cell Biol. 14:1994;181-188.
45. Webster M.K., Donoghue D.J. FGFR activation in skeletal disorders Too much of a good thing . Trends Genet. 13:1997;178-182.
46. Weksler N.B., Lunstrum G.P., Reid E.S., Horton W.A. Differential effects of fibroblast growth factor (FGF)-9 and FGF-2 on proliferation, differentiation and terminal differentiation of chondrocytic cells in vitro. Biochem J. 342:1999;677-682.
47. Wilkie A.O.M., Morriss-Kay G.M., Jones E.Y., Heath J.K. Functions of fibroblast growth factors and their receptors. Curr Biol. 5:1995;500-507.
48. Wiltfang J., Merten H.A. Ectopic bone formation with the help of growth factor bFGF. Journal Cranio-Maxillofac Surg. 24:1996;300-304.
49. Zhao W.G., Neufeld D.A. Bone regeneration after amputation stimulated by basic fibroblast growth factor in-vitro. In Vitro Cell Dev Biol. 32:1996;63-65.