Role of growth hormone (GH)-releasing hormone and somatostatin on leptin-induced GH secretion

Neuroendocrinology

Volumn 69, Issue 1, 1999, Pages 3-10

  Cairo, E ^d   Senaris R M ^d   Seoane, L M ^d   Frohman, L A ^a   Arimura, A ^b   Casanueva, F F ^d   Dieguez C ^c  

^a UNIVERSITY OF ILLINOIS   (United States)

^b TULANE UNIVERSITY   (United States)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^d NONE

Author keywords

Arcuate nucleus; Growth hormone; Growth hormone releasing hormone; Leptin; Somatostatin

Indexed keywords

GROWTH HORMONE RELEASING FACTOR; LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; SOMATOSTATIN;

ADIPOCYTE; ANIMAL EXPERIMENT; ARCUATE NUCLEUS; ARTICLE; BODY WEIGHT; CACHEXIA; CONTROLLED STUDY; DRUG EFFECT; ENERGY EXPENDITURE; FOOD INTAKE; GROWTH HORMONE RELEASE; HYPOTHALAMUS; INTRACARDIAC DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT;

ANIMALS; ARCUATE NUCLEUS; FASTING; FOOD DEPRIVATION; GROWTH HORMONE; GROWTH HORMONE-RELEASING HORMONE; HYPOPHYSECTOMY; HYPOTHALAMUS; IMMUNE SERA; LEPTIN; MALE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SOMATOSTATIN;

EID: 0004564368     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054397     Document Type: Article

References (35)

1. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P: Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks. Science 1995;269: 546-549.
2. Considine RV, Considine EL, Williams CJ, Nyce MR, Magosin SA, Baner JL, Rosato EL, Colberg J, Caro JF: Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity. J Clin Invest 1995;95:2986-2988.
3. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM: Weight-reducing effects of the plasma proteins encoded by the obese gene. Science 1995;269:543-546.
4. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F: Effects of the obese gene product on body weight regulation in ob/ob mice. Science 1995;269: 540-543.
5. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-432 (Erratum: Nature 1995;374:479).
6. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-432 (Erratum: Nature 1995;374:479).
7. Carro E, Señarís R, Considine RV, Casanueva FF, Diéguez C: Regulation of in vivo growth hormone secretion by leptin. Endocrinology 1997;138:2203-2206.
8. Hamilton BS, Paglia D, Kwan AYM, Deitel M: Increased obese mRNA expression in omental fat cells from massively obese humans. Nat Med 1995;1:953-956.
9. Lonnqvist F, Arner P, Nordfors L, Schalling M: Overexpression of the obese (ob) gene in adipose tissue of human obese subjects. Nat Med 1995;1:950-953.
10. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF: Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 1996;334:292-295.
11. Diéguez C, Casanueva FF. Influence of metabolic substrates and obesity on GH secretion. Trends Endocrinol Metab 1995;6:55-59.
12. Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Trayhurn P: Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization. FEBS Lett 1996;387:113-116.
13. Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Morgan PJ, Trayhurn P: Coexpression of leptin receptor and preproneuropeptide Y mRNA in the arcuate nucleus of mouse hypothalamus. J Neuroendocrinol 1996;8:733-735.
14. Schwartz MW, Seeley RJ, Campfield A, Burn P, Baskin DG: Identification of targets of leptin action in rat hypothalamus. J Clin Invest 1996; 98:1101-1106.
15. Kiyama H, Emson PC: Distribution of somatostatin mRNA in the rat nervous system as visualized by a novel non-radioactive in situ hybridization histochemistry procedure. Neuroscience 1990;38:223-244.
16. Meister B, Hokfelt T, Johansson O, Hulling A-L: Distribution of growth hormone-releasing factor, somatostatin and coexisting messengers in the brain; in Isaksson O, Binder C, Hall K, Hokfelt T (eds): Growth Hormone: Basic and Clinical Aspects. Amsterdam, Excerpta Medica, 1987, pp 29-52.
17. Merchenthaler I, Setalo G, Csontos C, Petrusz P, Flerko B, Negro-Vilar A: Combined retrograde tracing and immunocytochemical identification of luteinizing hormone-releasing hormone and somatostatin-containing neurones projecting to the median eminence in the rat. Endocrinology 1989;125:2812-2821.
18. Chomczynski P, Downs TR, Frohman LA: Feedback regulation of growth hormone (GH)-releasing hormone gene expression by GH in rat hypothalamus. Mol Endocrinol 1988;2: 236-241.
19. Rogers KV, Vician L, Steiner RA, Clifton DK: The effect of hypophysectomy and growth hormone administration on preprosomatostatin messenger ribonucleic acid in the periventricular nucleus of the rat hypothalamus. Endocrinology 1988;122:586-591.
20. Wood TL, Berelowitz M, Gelato MC, Roberts CT Jr, LeRoith D, Millard WJ, McKelvy JF: Hormonal regulation of rat hypothalamic neuropeptide mRNAs: Effect of hypophysectomy and hormone replacement on growth hormone-releasing factor, somatostatin and the insulin-like growth factors. Neuroendocrinology 1991; 53:298-305.
21. Frohman MA, Downs TR, Chomczynski P, Frohman LA: Cloning and characterization of mouse growth hormone-releasing hormone (GRH) complementary DNA. Increased GRH messenger RNA levels in growth hormone-deficient lit/lit mouse. Mol Endocrinol 1989;3: 1529-1536.
22. Burton KA, Kabigting EB, Clifton DK, Steiner RA: Growth hormone receptor messenger ribonucleic acid distribution in the adult male rat brain, and its colocalization in hypothalamic somatostatin neurons. Endocrinology 1992; 131:958-963.
23. Burton KA, Steiner RA, Clifton DK: Double-label in situ hybridization confirms that the GRF gene and the GH receptor gene are coexpressed in a subset of neurons in the arcuate nucleus. 74th Annual Meeting of the Endocrine Society, San Antonio 1992, abstr 1370.
24. Mallo F, Lamas JA, Casanueva FF. Diéguez C: Effect of retinoic acid deficiency on in vivo and in vitro GH response to GHRH in male rats. Neuroendocrinology 1992;55:642-647.
25. Vuyyuru L, Harrington L, Arimura A, Schubert ML: Reciprocal inhibitory paracrine pathways link histamine and somatostatin secretion in the fundus of the stomach. Am J Physiol 1997;273:G106-G111.
26. Katakami H, Downs TR, Frohman LA: Decreased hypothalamic growth hormone-releasing hormone content and pituitary responsiveness in hypothyroidism. J Clin Invest 1986;77: 1704-1711.
27. Señarís RM, Lago F, Coya R, Pineda J, Diéguez C: Regulation of hypothalamic somatostatin, growth hormone-releasing hormone, and growth hormone receptor messenger ribonucleic acid by glucocorticoids. Endocrinology 1996;137:5236-5241.
28. Paxinos G, Watson C: The Rat Brain in Stereotaxic Coordinates, ed 2. Sydney, Academic Press, 1986.
29. Tannenbaum GS, Rorstad O, Brazeau P: Effects of prolonged food deprivation on the ultradian growth hormone rhythm and immunoreactive somatostatin tissue levels in the rat. Endocrinology 1979;104:1733-1738.
30. Tannenbaum GS, Epelbaum J, Colle E, Brazeau P, Martin JB: Antiserum to somatostatin reverses starvation-induced inhibition of growth hormone but not insulin secretion. Endocrinology 1978;102:1909-1914.
31. Hugues JN, Enjalbert A, Moyse E, Shu C, Voirol MJ, Sebaoun J, Epelbaum J: Differential effects of passive immunization with somatostatin antiserum on adenohypophysial hormone secretions in starved rats. Endocrinol 1986;109:169-174.
32. Bruno JF, Olchovsky D, White JD, Leidy JW, Song J, Berelowitz M: Influence of food deprivation in the rat on hypothalamic expression of growth hormone-releasing factor and somatostatin. Endocrinology 1990;127:2111-2116.
33. Ahima RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E, Flier JS: Role of leptin in the neuroendocrine response to fasting. Nature 1996;382:250-255.
34. Robbins RJ, Leidy JW, Landon RM: The effects of growth hormone, prolactin, corticotropin, and thyrotropin on the production and secretion of somatostatin by hypothalamic cells in vitro. Endocrinology 1985;117:538-543.
35. Quintela M, Señarís RM, Heiman ML, Casanueva FF, Diéguez C: Leptin inhibits in vitro hypothalamic somatostatin secretion and somatostatin mRNA levels. Endocrinology 1997; 138:5641-5644.