Recirculating and marginal zone B cell populations can be established and maintained independently of primary and secondary follicles

Immunology and Cell Biology

Volumn 79, Issue 1, 2001, Pages 54-61

  Körner, Heinrich ^a   Winkler, Thomas H ^a   Sedgwick, Jonathon D ^b   Röllinghoff, Martin ^a   Basten, Antony ^c   Cook, Matthew C ^d  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b MERCK RESEARCH LABORATORIES   (United States)

^c CENTENARY INSTITUTE   (Australia)

^d UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

Author keywords

B cells; B 1 cells; Lymphotoxin ; Marginal zone; Spleen; TNF

Indexed keywords

BROXURIDINE; LYMPHOTOXIN; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; GERMINAL CENTER; HOMEOSTASIS; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PHENOTYPE; SPLEEN CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; B-LYMPHOCYTE SUBSETS; BONE MARROW CELLS; BROMODEOXYURIDINE; CELL LINEAGE; CELL SEPARATION; FLOW CYTOMETRY; IMMUNOGLOBULIN D; IMMUNOGLOBULIN M; LYMPHOTOXIN-ALPHA; MICE; MICE, INBRED C57BL; PHENOTYPE; SPLEEN; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0035134802     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1711.2001.00984.x     Document Type: Article

References (48)

1. Newly produced virgin B cells migrate to secondary lymphoid organs but their capacity to enter follicles is restricted
2. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell independent antigens
3. The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and the availability of T cell help
4. Outer PALS arrest and subsequent differentiation of both naive and tolerant Ig transgenic B cells is determined by B cell receptor occupancy
5. B-cell receptor regulation of peripheral B cells
6. Transfer of small resting B cells into immunodeficient hosts results in the selection of a self-renewing activated B cell population
7. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin
8. Lymphotoxin-α deficient mice: Effects on secondary lymphoid organ development and humoral immune responsiveness
9. Immune and inflammatory responses in TNFα-deficient mice: A critical requirement for TNFα in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centres, and in the maturation of the humoral immune response
10. Distinct roles for lymphotoxin-α and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue
11. Distinct roles in lymphoid organogensis for lymphotoxins α and β revealed in lymphotoxin β-deficient mice
12. Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice
13. Role of lymphotoxin and the type I TNF receptor in the formation of germinal centres
14. Lymphotoxin-α-deficient and TNF receptor-I deficient mice define developmental and functional characteristics of germinal centres
15. Crucial role of tumor necrosis factor receptor 1 expression on nonhematopoietic cells for B cell localization within the splenic white pulp
16. Lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin alpha-dependent fashion
17. Generation of splenic follicular structure and B cell movement in tumor necrosis factor-deficient mice
18. Lymphotoxin αβ and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen
19. Gene targeting in C57BL/6 ES cells. Successful germline transmission using recipient BALB/c blastocysts developmentally matured in vitro
20. Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development
21. Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity
22. FACS Analysis of B lymphopoiesis in mouse and human bone marrow
23. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals
24. Cell subpopulations identified by two-colour fluorescence analysis
25. Marginal zone B cells express CR1 and CR2 receptors
26. Memory B cells in T-dependent antibody responses colonise the splenic marginal zones
27. Peripheral B cell maturation. II. Heat-stable antigen (hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells
28. The Ly-1 B cell lineage
29. Mutant mice without B lymphocyte follicles
30. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
31. B-cell homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1
32. Lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement
33. Competition for follicular niches excludes self-reactive cells from the recirculating repertoire
34. Resource competition as a mechanism for B cell homeostatsis
35. Are murine marginal-zone macrophages the splenic white pulp analog of high endothelial venules?
36. CD22 regulates thymus-independent responses and the lifespan of B cells
37. Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice
38. Cells in the marginal zone of the spleen
39. Marginal zones: The major B cell compartment of rat spleens
40. Lymphocytes of splenic marginal zones: A distinct B cell lineage
41. Migrant μ+δ+ and static μ+δ- B lymphocyte subsets
42. Affinity maturation without germinal centres in lymphotoxin-α-deficient mice
43. Transfer of primitive stem/progenitor bone marrow cells from LI alpha-/- donors to wild-type hosts: Implications for the generation of architectural events in lymphoid B cell domains
44. Different macrophage populations distinguished by means of fluorescent polysaccharides. Recognition and properties of marginal zone macrophages
45. Immunomodulation with liposomes: The immune response elicited by liposomes with entrapped dichloromethylene-diphosphonate and surface-associated antigen or hapten
46. Lymphocyte migration in the spleen: The effect of macrophage elimination
47. Influence of lymphocytes on the presence and organization of dendritic cell subsets in the spleen
48. Production of immunoglobulin isotypes by Ly-1+ B cells in viable motheaten and normal mice