Role of chemokines in fungal infections

Medical Mycology

Volumn 39, Issue 1, 2001, Pages 41-50

  Traynor, T R ^a   Huffnagle, G B ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Chemokine; Chemotaxis; Fungi; Leukocyte

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR;

ASPERGILLUS; BLASTOMYCES; CANDIDA ALBICANS; CELL POPULATION; CELLULAR IMMUNITY; CHEMOKINESIS; CHEMOTAXIS; COCCIDIOIDES; CRYPTOCOCCUS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EFFECTOR CELL; HISTOPLASMA; HUMAN; HUMAN CELL; IN VIVO STUDY; LEUKOCYTE ACTIVATION; MOLECULAR BIOLOGY; MYCOSIS; NONHUMAN; PARACOCCIDIOIDES; PNEUMOCYSTIS; REVIEW; SIGNAL TRANSDUCTION;

AJELLOMYCES; ASPERGILLUS; BLASTOMYCES; CANDIDA; CANDIDA ALBICANS; COCCIDIOIDES; FUNGI; PARACOCCIDIOIDES; PNEUMOCYSTIS;

EID: 0035126228     PISSN: 13693786     EISSN: None     Source Type: Journal    
DOI: 10.1080/mmy.39.1.41.50     Document Type: Review

References (90)

1. Rossi D. Zlolnik A. The biology of chemokines and (heir receptors. Anna Rev Immunol 2000; 18: 217-242.
2. Zlotnik A, Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 2000; 12: 121-127.
3. O'Garra A, McEvoy LM. Zlotnik A. T-cell subsets: chemokine receptors guide the way. Curr Biol 1998; 8: R646-649.
4. Murphy PM Baggiolini M, Charo IF. et al. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev 2000; 52: 145-176.
5. Casadevall A, Perfect JR. Ecology of Cryptococcus neoformans. In: Cryptococcus neoformans. Washington, DC: ASM Press. 1998: 41-70.
6. Casadevall A, Perfect JR. Epidemiology. In: Cryptococcus neoformans. Washington, DC: ASM Press, 1998: 351-380.
7. Diamond RD. Cryptococcus neoformans. In: GL Mandell, JE Bennett, R Dolin, eds. Principles and Practice of Infectious Diseases. New York: Churchill Livingston, 1995: 2331-2340.
8. Huffnagle GB, McNeil LK. Dissemination of Cryptococcus neoformans to the central nervous system: role of chemokines, Thl immunity and leukocyte recruitment. J Neitrovirol 1999; 5: 76-81.
9. Huffnagle GB, Yates JL, Lipscomb MF. Immunity to a pulmonary Cryptococcus neoformans infection requires both CD4+ and CD8+ T cells. J Exp Med 1991; 173: 793-800.
10. Huffnagle GB, Lipscomb MF, Lovchik JA, et al. The role of CD4+ and CD8+ T cells in the protective inflammatory response to a pulmonary cryptococcal infection. J Leukoc Biol 1994:55:35-42.
11. Salkowski CA, Balish E. Inflammatory responses to cryptococcosis in congenially athymic mice. J Leukoc Biol 1991: 49: 533-541.
12. Traynor TR. Kuziel WA, Toews GB, et al. CCR2 expression determines Tl versus T2 polarization during pulmonary Cryptococcus neoformans infection. J Immunol 2000; 164: 2021-2027.
13. Casadevall A, Perfect JR. Physical defenses and nonspecific immunity. In: Cryptococcus neoformans. Washington, DC: ASM Press, 1998: 177-222.
14. Huffnagle GB, Toews G. Mechanism of macrophage recruitment into infected lungs. In: Lipscomb MF, Russell SW, eds. Lung Macrophages and Dendritic Cells in Health and Disease. New York: Marcel Dekker, 1997: 373-407.
15. Huffnagle GB, Lipscomb MF. Cells and cytokines in pulmonary cryptococcosis. Res Immunol 1998; 149: 387-396.
16. Huang C, Levitz SM. Stimulation of macrophage inflammatory protein-1 alpha, macrophage inflammatory protein-lbeta, and RANTES by Candida albicans and Cryptococcus neoformans in peripheral blood mononuclear cells from persons with and without human immunodeficiency virus infection. J Infect Dis 2000; 181: 791-794.
17. Levitz SM, North EA. Jiang Y, et al. Variables affecting production of monocyte chemotactic factor 1 from human leukocytes stimulated with Cryptococcus neoformans. Infect Immun 1997: 65: 903-908.
18. Retini C, Vecchiarelli A, Monari C, et al. Capsular polysaccharide of Cryptococcus neoformans induces proinflammatory cytokine release by human neutrophils. Infect Immun 1996; 64: 2897-2903.
19. Vecchiarelli A, Retini C, Casadevall A, et al. Involvement of C3a and C5a in interleukin-8 secretion by human polymorphonuclear cells in response to capsular material of Cryptococcus neoformans. Infect Immun 1998; 66:4324-4330.
20. Lipovsky MM. Gekker G, Hu S, et al. Cryptococcal glucuronoxylomannan induces interleukin (IL)-8 production by human microglia but inhibits neutrophil migration toward IL-8. J Infect Dis 1998; 177: 260-263.
21. Chaka W. Heyderman R, Gangaidzo I, et al. Cytokine profiles in cerebrospinal fluid of human immunodeficiency virus-infected patients with cryptococcal meningitis: no leukocytosis despite high interleukin-8 levels. University of Zimbabwe Meningitis Group.J Infect Dis 1997; 176: 1633-1636.
22. Huffnagle GB. Stricter RM. Standiford TJ, et al. The role of monocyte chemotactic protein-1 (MCP-1) in the recruitment of monocytes and CD4+ T cells during a pulmonary Cryptococcus neoformans infection.J Immunol 1995: 155: 4790-4797.
23. Huffnagle GB. Role of cytokincs in T cell immunity to a pulmonary Crvptococcus neoformans infection. Biol Signals 1996: 5: 215-222.
24. Huffnagle GB. Stricter RM, McNeil LK, et at. Macrophage inflammatory protein-(alpha (MIP-1 alpha) is required for the efferent phase of pulmonary cell-mediated immunity to a Crvptococcus neoformans infection. J Immunol 1997: 159: 318-327.
25. Boring L. Gosling J. Monteclaro FS, et al Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1 ) and murine macrophage inflammatory protein 1 alpha receptors: evidence for two closely linked C-C chemokine receptors on chromosome 9. J Biol Chem 1996; 271: 7551-7558.
26. Hoag KA. Lipscomb MF. Izzo AA, et al. IL-12 and IFN-gamma are required for initiating the protective Thl response to pulmonary cryptococcosis in resistant C.B-17 mice. Am J Respir Cell Moi Biol 1997; 17: 733-739.
27. Kawakami K. Qureshi MH, Zhang T, et al. Interferon-gamma (IFN-gamma)-dependent protection and synthesis of chemoattractants for mononuclear leucocytes caused by IL-12 in the lungs of mice infected with Cryptococcus neoformans. Clin Exp Immunol 1999; 117: 113-122.
28. Kawakami K, Tohyama M. Xie Q. et al. IL-12 protects mice against pulmonary and disseminated infection caused by Crvptococcus neoformans. Clin Exp Immunol 1996; 104: 208-214.
29. Mantovani A. The chemokine system: redundancy for robust outputs. Immunol Today 1999; 20: 254-257.
30. Schweickart VL, Epp A, Raport CI, et al. CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines.J Biol Chem 2000; 275: 9550-9556.
31. Hogaboam CM, Lukacs NW, Chensue SW, et al. Monocyte chemoattractant protein-1 synthesis by murine lung fibroblasts modulates CD4+ T cell activation. J Immunol 1998; 160: 4606-4614.
32. Karpus WJ. Lukacs NW, Kennedy KJ, et al. Differential CC chemokine-induced enhancement of T helper cell cytokine production. J Immunol 1997; 158: 4129-4136.
33. Gu L, Tseng S, Horner RM. et al. Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1. Nature 2000; 404:407-411.
34. Doyle HA, Murphy JW. Role of the C-C chemokine, TCA3, in the protective anticryptococcal cell-mediated immune response. J Immunol 1999; 162: 4824-4833.
35. Doyle HA, Murphy JW. MIP-1 alpha contributes to the anticryptococcal delayed-type hypersensitivity reaction and protection against Cryptococcus neoformans. J Leukoc Biol 1997: 61: 147-155.
36. Huffnagle GB, Toews GB. Burdick MD, et al. Afferent phase production of TNF-alpha is required for the development of protective T cell immunity to Cryplococcus neoformans. J Immunol 1996; 157: 4529-4536.
37. Kawakami K, Qifeng X, Tohyama M, el al. Contribution of tumour necrosis factor-alpha (TNF-alpha) in host defence mechanism against Cryptococcus neoformans. Clin Exp Immunol 1996; 106: 468-474.
38. Huffnagle GB. Strieter RM. Kunkel SL, et al. The role of chemokines in pneumonia. In: Koch AE. Strieter RM. eds. Chemokines in Disease. Austin, TX: RG Landes, 1996: 151-168.
39. Strieter RM, Kunkel SL. Chemokines. In: RG Crystal. JB West, eds. The Lung. Philadelphia: Lippincott-Raven, 1997: 155-185.
40. Curtis JL. Huffnagle GB, Chen GH, et al. Experimental murine pulmonary cryptococcosis. Differences in pulmonary inflammation and lymphocyte recruitment induced by two encapsulated strains of Crvplococcus neoformans. Lab Invest 1994; 71: 113-126.
41. Huffnagle GB, Chen GH, Curtis JL, et al. Down-regulation of the afferent phase of T cell-mediated pulmonary inflammation and immunity by a high melanin-producing strain of Crypwcoccus neoformans. J Immunol 1995; 155: 3507-3516.
42. Kawakami K, Shibuya K. Qureshi MH, et al. Chemokine responses and accumulation of inflammatory cells in the lungs of mice infected with highly virulent Cryptococcus neoformans: effects of interleukin-12. FEMS Immunol Med Microbiol 1999; 25: 391-402.
43. Stevens DA. Walsh TJ. Bistoni F. el al. Cytokines and mycoses Med Mycol 1998; 36: 174-182.
44. Vazquez-Torres A. Balish E. Macrophages in resistance to candidiasis. Microbiol Mol Biol Rev 1997; 61: 170-192.
45. Romani L. Immunity to Candida albicans: Thl. Th2 cells and beyond. Curr Opin Microbiol 1999; 2: 363-367.
46. Murphy JW, Bistoni F, Deepe GS, et al. Type 1 and type 2 cytokines: from basic science to fungal infections. Med Mvcol 1998:36:109-118.
47. Lai S. Mitsuyama M. Miyata M. et al. Pulmonary defence mechanism in mice. A comparative role of alveolar macrophages and polymorphonuclear cells against infection with Candida albicans. J Clin Lab Immunol 1986; 19: 127-133.
48. Edwards JE Jr, Rotrosen D, Fontaine JW. et al. Neutrophilmediated protection of cultured human vascular endothelial cells from damage by growing Candida albicans hyphae. Blood 1987:69:1450-1457.
49. Kullberg BJ. Netea MG, Vonk AG, et al Modulation of neutrophil function in host defense against disseminated Candida albicans infection in mice. FEMS Immunol Med Microbiol 1999: 26: 299-307.
50. Sawyer RT. Harmsen AG. The relative contribution of resident pulmonary alveolar macrophage and inflammatory polymorphonuclear neutrophils in host resistance to pulmonary infection by Candida albicans. Mycopathologia 1989; 108: 95-105.
51. Romani L. Bistoni F, Puccetti P. Initiation of T-helper cell immunity to Candida albicans by IL-12: the role of neutrophils. Chem Immunol 1997; 68: 110-135.
52. Rosseau S. Hammerl P. Maus U, et al. Surfactant protein A down-regulates proinflammatory cytokine production evoked by Candida albicans in human alveolar macrophages and monocytes. J Immunol 1999; 163: 4495-4502.
53. Jiang Y, Russell TR, Graves DT. et al. Monocyte chemoattractant protein 1 and interleukin-8 production in mononuclear cells stimulated by oral microorganisms. Infect Immun 1996; 64: 4450-4455.
54. Castro M, Bjoraker JA, Rohrbach MS. et al. Candida albicans induces the release of inflammatory mediators from human peripheral blood monocytes. Inflammation 1996; 20: 107-122.
55. Yamamoto Y, Klein TW. Friedman H. Involvement of mannose receptor in cytokine interleukin-lbeta (IL-lbeta), IL-6. and granulocyte-macrophage colony-stimulating factor responses, but not in chemokine macrophage inflammatory protein Ibeta (MIP-lbeta), MIP-2. and KC responses, caused by attachment of Candida albicans to macrophages. Infect Immun 1997; 65: 1077-1082.
56. Willcox MD, Webb BC. Thakur A. et al. Interactions between Candida species and platelets.J Mfil Microbiol 1998; 47: 103-110.
57. Hachicha M. Rathanaswami P, Naccache PH. et al. Regulation of chemokine gene expression in human peripheral blood neutrophils phagocytosing microbial pathogens.J Immunol 1998; 160:449-154.
58. Filler SG, Pfunder AS, Spellberg BJ, el at. Candida albicans stimulates cytokine production and leukocyte adhesion molecule expression by endothelial cells. Infect Immun 1996; 64: 2609-2617.
59. Saavedra M, Taylor B, Lukacs N, et al Local production of chemokines during experimental vaginal candidiasis. Infect Immun 1999; 67: 5820-5826.
60. Sobel JD, Hasegawa A, Debernardis F. et al. Selected animal models: vaginal candidosis. Pneumocystis pneumonia, dermatophytosis and trichosporosis. Med Mycol 1998; 36: 129-136.
61. King AG, Johanson K, Frey CL, et al. Identification of unique truncated KC/GRO beta chemokines with potent hematopoietic and anti-infective activities. J Immunol 2000; 164: 3774-3782.
62. DeMarsh PL, Sucoloski SK. Frey CL, et al. Efficacy of the hematoregulatory peptide SK&F 107647 in experimental systemic Candida albicans infections in normal and immunosuppressed mice. Immunopharmacology 1994; 27: 199-206.
63. Musso T, Calosso L, Zucca M, et al. Interleukin-15 activates proinflammatory and antimicrobial functions in polymorphonuclear cells. Infect Immun 1998; 66: 2640-2647.
64. Kurup VP, Grunig G, Knutsen AP, et al. Cytokines in allergic bronchopulmonary aspergillosis. Res Immunol 1998; 149: 466-477.
65. Cenci E, Mencacci A. d'Ostiani CF, et al. Cytokine- and T-helper-dependent immunity in murine aspergillosis. Res Immunol 1998; 149: 445-454.
66. Sallusto F, Mackay CR, Lanzavecchia A. The role of chemokine receptors in primary, effector, and memory immune responses. Annu Rev Immunol 2000; 18: 593-620.
67. Kurup VP, Guo J, Murali PS, et al Immunopathologic responses to Aspergillus antigen in interleukin-4 knockout mice. J Lab Clin Med 1997; 130: 567-575.
68. Hogaboam CM, Gallinat CS, Taub DD, et al. Immunomodulatory role of CIO chemokine in a murine model of allergic bronchopulmonary aspergillosis. J Immunol 1999; 162: 6071-6079.
69. Roilides E, Katsifa H, Walsh TJ. Pulmonary host defences against Aspergillus fumigatus. Res Immunol 1998; 149: 454-465.
70. Borger P, Koeter GH, Timmerman JA, et al. Proteases from Aspergillus fumigatus induce interleukin (IL)-6 and IL-8 production in airway epithelial cell lines by transcriptional mechanisms. J Infect Dis 1999; 180: 1267-1274.
71. Tomee JF, Wierenga AT, Hiemstra PS, el al. Proteases from Aspergillus fumigatus induce release of proinflammatory cytokines and cell detachment in airway epithelial cell lines. J Infect Dis 1997; 176: 300-303.
72. Richardson MD, Patel M. Stimulation of neutrophil phagocytosis of Aspergillus fumigatus conidia by interIeukin-8 and Nformylmethionyl-leucylphenylalanine. J Med Vet Mycol 1995; 33:99-104.
73. Shahan TA, Sorenson WG, Paulauskis JD, el al. Concentrationand time-dependent uprcgulation and release of the cytokines MIP-2, KC, TNF. and MIP-lalpha in rat alveolar macrophages hy fungal spores implicated in airway inflammation. Am ,1 Respir Cell Mol Biol 1998; 18: 435-440.
74. Schelenz S. Smith DA. Bancroft GJ. Cytokine and chemokine responses following pulmonary challenge with Aspergillus fiimigalns: obligatory role of TNF-alpha and GM-CSF in neutrophil recruitment. Med Mvcol 1999; 37: 183-194,
75. Mehrad B. Stricter RM, Standiford TJ. Role of TNF-alpha in pulmonary host defense in murine invasive aspergillosis.J Immunol 1999; 162: 1633-1640.
76. Mehrad B. Stricter RM, Moore TA, et al. CXC chemokine receptor-2 ligands arc necessary components of neutrophilmediated host defense in invasive pulmonary aspergillosis. J Immunol 1999; 163: 6086-6094.
77. Gao JL, Wynn TA, Chang Y, et al. Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1.J Exp Med 1997: 185: 1959-1968.
78. Schliep TC, Yarrish RL. Pneumocystis carinii pneumonia. Semin Respir Infect 1999; 14: 333-343.
79. Martin WJ. Pneumocystis carinii: the art and science of survival in the hostile environment of the alveolar spaces. Semin Respir Infect 1998; 13: 348-352.
80. Beck JM, Harmsen AG. Lymphocytes in host defense against Pneumocystis carinii. Semin Respir Infect 1998; 13: 330-338.
81. Wright TW, Johnston CI, Harmsen AG. et al. Chemokine gene expression during Pneumocystis cörimV-driven pulmonary inflammation. Infect Immun 1999; 67: 3452-3460.
82. Roths JB, Sidman CL. Both immunity and hyperresponsiveness to Pneumocystis carinii result from transfer of CD4+ but not CD8+ T cells into severe combined immunodeficiency mice. J Clin Invest 1992; 90: 673-678.
83. Wright TW, Johnston CJ. Harmsen AG, et al. Analysis of cytokine mRNA profiles in the lungs of Pneumocystis cariniiinfected mice. Am J Respir Cell Mol Biol 1997; 17: 491-500.
84. Benfield TL, van Steenwijk R, Nielsen TL, et al. Interleukin-8 and eicosanoid production in the lung during moderate to severe Pneumocystis carinii pneumonia in AIDS: a role of interleukin-8 in the pathogenesis of P. carinii pneumonia. Respir Med 1995: 89: 285-290.
85. Lipschik GY. Doerfler ME, Kovacs JA, et al. Leukotriene B4 and interleukin-8 in human immunodeficiency virus-related pulmonary disease. Chest 1993; 104: 763-769.
86. Benfield TL, Vestbo J. Junge J, et al. Prognostic value of interleukin-8 in AIDS-associated Pneumocystis carinii pneumonia. Am J Respir Crit Care Med 1995; 151: 1058-1062.
87. Benfield TL. Kharazmi A, Larsen CG. et al. Neutrophil chemotactic activity in bronchoalveolar lavage fluid of patients with AIDS-associated Pneumocystis carinii pneumonia. Scand J Infect Dis 1997; 29: 367-371.
88. Benfield TL, Lundgren B. Shelhamer JH, et al. Pneumocystis carinii major surface glycoprotein induces interleukin-8 and monocyte chemoattractant protein-1 release from a human alveolar epithelial cell line. Eur J Clin Invest 1999; 29: 717-722.
89. Lipschik GY, Treml JF, Moore SD. Pneumocystis carinii glycoprotein A stimulates interleukin-8 production and inflammatory cell activation in alveolar macrophages and cultured monocytes.J Eukaryot Microbiol 1996; 43: 16S-17S.
90. Benfield TL, Lundgren B, Levine SJ, et al. The major surface glycoprotein of Pneumocystis carinii induces release and gene expression of interleukin-8 and tumor necrosis factor alpha in monocytes. Infect Immun 1997: 65: 4790-4794.