Cytokine and chemokine responses following pulmonary challenge with Aspergillus fumigatus: Obligatory role of TNF-α and GM-CSF in neutrophil recruitment

Medical Mycology

Volumn 37, Issue 3, 1999, Pages 183-194

  Schelenz, Silke ^a,c   Smith, D A ^b   Bancroft, G J ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Aspergillus fumigatus; Chemokines; Cytokines; Lung

Indexed keywords

CHEMOKINE; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; INFLAMMATORY CELL; LUNG ASPERGILLOSIS; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PROTEIN EXPRESSION;

ANIMALS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CELLS, CULTURED; CHEMOKINE CCL2; CRICETINAE; DISEASE MODELS, ANIMAL; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERLEUKIN-1; LUNG; MACROPHAGE INFLAMMATORY PROTEIN-1; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED BALB C; MONOKINES; NEUTRALIZATION TESTS; NEUTROPHILS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; ASPERGILLUS FUMIGATUS; MURINAE;

EID: 0032803750     PISSN: 13693786     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-280X.1999.00219.x     Document Type: Article

References (42)

1. Weinberger M, Elattar I, Marshall D, et al. Patterns of infection in patients with aplastic anaemia and the emergence of Aspergillus as a major cause of death. Medicine 1992; 71: 24-43.
2. Gustafson TL, Schaffner W, Lavely GB, et al. Invasive aspergillosis in renal transplant recipients: correlation with corticosteroid therapy. J Infect Dis 1983; 148: 230-238.
3. Schaffner A, Douglas H, Baude A. Selective protection against conidia by mononuclear and against mycelia by polymorphnuclear phagocytes in resistance to Aspergillus: observations on these two lines of defence in vivo and in vitro with human and mouse phagocytes. J Clin Invest 1982; 69: 617-631.
4. Denning DW, Follansbee SE, Scolaro M, et al. Pulmonary aspergillosis in the acquired immunodeficiency syndrome. New Engl J Med 1991; 324: 654-662.
5. Waldorf AR, Levitz SM, Diamond RD. In vivo bronchoalveolar macrophages against Rhizophus oryzae and Aspergillus fumigatus. J Inject Dis 1984; 150: 752-760.
6. Schaffner A, Douglas H, Braude AI, et al. Killing of Aspergillus spores depends on the anatomical source of the macrophage. Infect Immun 1983; 42: 1109-1115.
7. Futenma M, Kawakami K, Saito A. Production of tumor necrosis factor-α in granulocytopenic mice with pulmonary candidiasis and its modification with granulocyte colony-stimulating factor. Microbiol Immunol 1995; 39: 411-417.
8. Sawyer RT, Harmsen AG. The relative contribution of resident pulmonary alveolar macrophage and inflammatory polymorphonuclear neutrophils in host resistance to pulmonary infection by Candida albicans. Mycopathologia 1989; 108: 95-105.
9. Stricter RM, Standiford TJ, Huffnagle GB, et al. The good, the bad, and the ugly. The role of chemokines in models of human disease. J Immunol 1996; 156: 3583-3586.
10. Collins HL, Bancroft GJ. Cytokine enhancement of complement-dependent phagocytosis by macrophages: synergy of tumor necrosis factor-α and granulocyte-macrophage colony-stimulating factor for phagocytosis of Cryptococcus neoformans. Eur J Immunol 1992; 22: 1447-1454.
11. + T cells during a pulmonary Cryptococcus neoformans infection. J Immunol 1995; 155: 4790-4797.
12. Louie A, Baltch A, Smith RP, et al. Tumor necrosis factor alpha has a protective role in a murine model of systemic candidiasis. Infect Immun 1994; 62: 2761-2772.
13. Nagai H, Guo J, Choi H, et al. Interferon-γ and tumor necrosis factor-α protect mice from invasive aspergillosis. J Infect Dis 1995; 172: 1554-1560.
14. Cross CE, Bancroft GJ. Ingestion of acapsular Cryptococcus neoformans occurs via mannose and β-glucan receptors, resulting in cytokine production and increased phagocytosis of the encapsulated form. Infect Immun 1995; 63: 2604-2611.
15. Murphy E, Hieny S, Sher A, et al. Detection of in vivo expression of interleukin-10 using a semi-quantitative polymerase chain reaction method in Schistosoma mansoni infected mice. J Immunol Methods 1993; 162: 211-223.
16. O'Garra A, Stapleton G, Dhar V, et al. Production of cytokines by mouse B cells: B lymphomas and normal B cells produce IL-10. Int Immunol 1990; 2: 821-826.
17. + T cells during initiation of infection. J Exp Med 1994; 179: 447-456.
18. Sonouchi K, Hamilton TA, Tannenbaum CS, et al. Chemokine gene expression in the murine renal cell carcinoma, RENCA, following treatment in vivo with interferon-α and interleukin-2. Am J Pathol 1994; 144: 747-755.
19. Dixon DM, Polak A, Walsh TJ. Fungus dose-dependent primary pulmonary aspergillosis in immunosuppressed mice. Infect Immun 1989; 57: 1452-1456.
20. Hector RF, Yee E, Collins MS. Use of DBA/2N mice in models of systemic candidiasis and pulmonary and systemic aspergillosis. Infect Immun 1990; 58: 1476-1478.
21. Diamond RD, Clark RA. Damage to Aspergillus fumigatus and Rhizopus oryzae hyphae by oxidative and nonoxidative microbicidal products of human neutrophils in vitro. Inject Immun 1982; 38: 487-495.
22. Standiford TJ, Kunkel SL, Greenberger MJ, et al. Expression and regulation of chemokines in bacterial pneumonia. J Leukoc Biol 1996; 59: 24-28.
23. Taramelli D, Malabara MG, Sala G, et al. Production of cytokine by alveolar and peritoneal macrophages stimulated by Aspergillus fumigatus conidia and hyphae. J Med Vet Mycol 1996; 34: 49-56.
24. Kan VL, Bennett JE. Lectin-like attachment sites on murine pulmonary alveolar macrophages bind Aspergillus fumigatus conidia. J Infect Dis 1988; 158: 407-414.
25. Hoffman OA, Standing JE, Limper AH. Pneumocystis carinii stimulates tumor necrosis factor-α release from alveolar macrophages through a β-glucan-mediated mechanism. J Immunol 1993; 150: 3932-3940.
26. Malaviya R, Ikeda T, Ross E, et al. Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α. Nature 1996; 286: 77-80.
27. Tracey KJ, Cerami A. Cachectin tumor necrosis factor and other cytokines in infectious disease. Curr Opin Immunol 1989; 1: 454-461.
28. Djeu JY, Blanchard DK, Halkias D, et al. Growth inhibition of Candida albicans by human polymorphonuclear neutrophils: activation by interferon-γ and tumor necrosis factor. J Immunol 1986; 137: 2980-2984.
29. Ferrante A. Tumor necrosis factor alpha potentiates neutrophil antimicrobial activity: increased fungicidal activity against Torulopsix glabrata and Candida albicans and associated increase in oxygen radical production and lysosomal enzyme release. Infect Immun 1989; 57: 2115-2122.
30. Marini M, Soloperto M, Mezzetti M, et al. Interleukin-1 binds to specific receptors on human bronchial epithelial cells and upregulates granulocyte/macrophage colony-stimulating factor synthesis and release. Am J Respir Cell Mol Biol 1991; 4: 519-524.
31. Bodey GP. The potential role of granulocyte-macrophage colony stimulating factor in therapy of fungal infections: a commentary. Eur J Clin Microbiol Inject Dis 1994; 13: 363-366.
32. Roilides E, Holmes A, Blake C, et al. Antifungal activity of elutriated human monocytes against Aspergillus fumigatus hyphae: enhancement by granulocyte-macrophage colony-stimulating factor and interferon-gamma. J Infect Dis 1994; 170: 894-899.
33. Chen G-H, Curtis JL, Mody CH, et al. Effect of granulocyte-macrophage colony-stimulating factor on rat alveolar macrophage anticryptococcal activity in vitro. J Immunol 1994; 152: 724-734.
34. Oppenheim JJ, Zachariae COC, Mukaida N, et al. Properties of the novel proinflammatory supergene intercrine cytokine family. Ann Rev Immunol 1991; 9: 617-647.
35. Friedland JS, Shattock RJ, Griffin GE. Phagocytosis of Mycobacterium tuberculosis or particulate stimuli by human monocytic cells induces equivalent monocyte chemotactic protein-1 gene expression. Cytokine 1993; 5: 150-156.
36. Rhoades ER, Cooper AM, Orme IM. Chemokine response in mice infected with Mycobacterium tuberculosis. Infect Immun 1995; 63: 3871-3877.
37. Greenberger MJ, Stricter RM, Kunkel SL, et al. Neutralization of macrophage inflammatory protein-2 attenuates neutrophil recruitment and bacterial clearance in murine Klebsiella pneumonia. J Infect Dis 1996; 173: 159-165.
38. Fahey TJ III, Tracey KJ, Tekamp-Olson P, et al. Macrophage inflammatory protein-1 modulates macrophage function. J Immunol 1992; 148: 2764-2769.
39. Murphy JW, Wu-Hsieli BA, Singer-Vermes LM, et al. Cytokines in the host to mycotic agents. J Med Vet Mycol 1994; 32: 203-210.
40. Brown Z, Gerritsen ME, Carley WW, et al. Chemokine gene expression and secretion by cytokine-activated human microvascular endothelial cells. Differential regulation of monocyte chemoattractant protein-1 and interleukin-8 in response to interferon-gamma. Am J Pathol 1994; 145: 913-921.
41. Driscoll KE, Hassenbein DG, Carter JM, et al. TNF alpha and increased chemokine expression in rat lung after particle exposure. Toxicol Lett 1995; 82: 483-489.
42. Lukacs NW, Kunkel SL, Allen R, et al. Stimulus and cell-specific expression of C-X-C and C-C chemokines by pulmonary stromal cell populations. Am J Physiol 1995; 268: L856-L861.