Exploration of mosquito immunity using cells in culture

Insect Biochemistry and Molecular Biology

Volumn 31, Issue 3, 2001, Pages 263-278

  Fallon, Ann M ^a   Sun, Dongxu ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Cecropin; Defensin; Established cell line; Hemocyte; Immune response; Innate immunity; Lysozyme; Transferrin

Indexed keywords

ANTI INFECTIVE AGENTS; ANTIINFECTIVE AGENT; CECROPIN; DEFENSIN; INSECT PROTEIN; LYSOZYME; PROPHENOL OXIDASE; TRANSFERRIN; UNCLASSIFIED DRUG;

AEDES; AMINO ACID SEQUENCE; ANIMAL; ANIMAL CELL; CELL LINE; CONFERENCE PAPER; IMMUNOREACTIVITY; MOLECULAR GENETICS; MOSQUITO; NONHUMAN; PARASITE IMMUNITY; PHAGOCYTOSIS; SPECIES DIFFERENCE;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; CELL LINE; CULICIDAE; DEFENSINS; INSECT PROTEINS; MOLECULAR SEQUENCE DATA; MURAMIDASE; TRANSFERRIN;

AEDES AEGYPTI; AEDES ALBOPICTUS; HEXAPODA; INSECTA; MAMMALIA;

EID: 0035112133     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0965-1748(00)00146-6     Document Type: Article

References (136)

1. Immunology: Improving on nature in the twenty-first century
2. Basic methods for the study of phagocytosis
3. Transferrin trojan horses as a rational approach for the biological delivery of therapeutic peptide domains
4. Tissue-specific regulation by ecdysone: Distinct patterns of Eip28/29 expression are controlled by different ecdysone response elements
5. Antibacterial activity of multiple antigen peptides homologous to a loop region in human lactoferrin
6. Dendritic cells and the control of immunity
7. Serum-free cell culture: A unifying approach
8. Macrokines: Invertebrate cytokine-like molecules?
9. Immunity and the invertebrates
10. Aedes aegypti: Characterization of a hemolymph polypeptide expressed during melanotic encapsulation of filarial worms
11. The postembryonic development of Drosophila
12. Antibacterial and antimalarial properties of peptides that are cecropin-melittin hybrids
13. Transferrin: Evolution and genetic regulation of expression
14. HLA-E binds to natural killer cell receptors CD94/NKG2A. B and C
15. Role of the integument in insect immunity: Epicuticular abrasion and induction of cecropin synthesis in cuticular epithelial cells
16. Insect cell and tissue culture
17. Drosophila cellular immunity against parasitoids
18. Antibacterial and antiviral factors in arthropod hemolymph
19. Purification of an insect defensin from the mosquito. Aedes aegypti
20. Molecular characterization of a defensin gene from the mosquito. Aedes aegypti
21. Cloning and characterization of cDNAs encoding the antibacterial peptide, defensin A. from the mosquito. Aedes aegypti
22. Hemocyte population changes during the immune response of Aedes aegypti to inoculated microfilariae of Dirofilaria immitis
23. Mariner transposition and transformation of the yellow fever mosquito. Aedes aegypti
24. Genetic modification of mosquitoes
25. Genetic selection of a Plasmodium-refractory strain of the malaria vector, Anopheles gambiae
26. Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin
27. Molecular immune responses of the mosquito Anopheles gambiae to bacteria and malaria parasites
28. Structure, classification and functions of insect haemocytes
29. Isolation and characterization of a mosquito ferritin and cloning of a cDNA that encodes one subunit
30. Midgut antibacterial defenses in Manduca sexta following infection and during metamorphosis
31. The non-enzymatic microbicidal activity of lysozymes
32. Adaptive humoral immunity in the American cockroach
33. Insect immune gene regulation
34. Optimization of gene transfer in cultured insect cells
35. Transfection of cultured mosquito cells
36. Ribosomal DNA structure in Aedes mosquitoes (Diptera: Culicidae) and their cell lines
37. The biochemistry and genetics of mosquito cells in culture
38. The instructive role of innate immunity in the acquired immune response
39. A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway
40. Phagocytosis of Escherichia coli by insect hemocytes requires both activation of the Ras/mitogen-activated protein kinase signal transduction pathway for attachment and β3 integrin for internalization
41. Immunity proteins from mosquito cell lines include three defensin A isoforms from Aedes aegypti and a defensin D from Aedes albopictus
42. Immune activation up-regulates lysozyme gene expression in Aedes aegypti mosquito cell culture
43. The Drosophila melanogaster immunosuppressive tumorous blood cell line mbn-2
44. Mode of action of the antibacterial cecropin B2: A spectrofluorometric study
45. D-Valine as a selective agent for normal human and rodent epithelial cells in culture
46. Biological mediators of insect immunity
47. Serine proteases as mediators of mosquito immune responses
48. Humoral encapsulation in insects
49. Establishment of four strains of cells from insect tissues grown in vitro
50. The cecropin locus: Cloning and expression of a gene cluster encoding three antibacterial peptides in Hyalophora cecropia
51. Insect immunocytes and other hemocytes: Roles in cellular and humoral immunity
52. Effects of magainins and cecropins on the sporogonic development of malaria parasites in mosquitoes
53. Observations on the living developing nerve fiber
54. Variation in hemocyte populations in various developmental stages of Blattella germanica (L.) (Dictyoptera: Blatellidae)
55. Sequence specificity and transcriptional activation in the binding of lactoferrin to DNA
56. Methods for distinguishing ingested from adhering particles
57. Secretion of an inducible cecropin-like activity by cultured mosquito cells
58. Immune responsiveness in vector insects
59. Purification, characterization, and cDNA cloning of a novel growth factor from the conditioned medium of NIH-Sape-4, an embryonic cell line of Sarcophaga peregrina (Flesh fly)
60. Immune reactions in Drosophila and other insects: A model for innate immunity
61. Identification of a distinct antibacterial domain within the N-lobe of ovo-transferrin
62. The role of microbial pattern recognition in self: Nonself discrimination in innate and adaptive immunity
63. Stable, transposon-mediated transformation of the yellow fever mosquito. Aedes aegypti, using the Hermes element from the housefly
64. In vitro cytocidal effect of novel lytic peptides on Plasmodium falciparum and Trypanosoma cruzi
65. Adjacent GATA and κB-like motifs regulate the expression of a Drosophila immune gene
66. Analysis of a lysozyme gene from the malaria vector mosquito. Anopheles gambiae
67. Insect haemolymph proteins
68. Insect immunity. Two 17 bp repeats nesting a κB-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila
69. Drosophila S2 system for heterologous gene expression
70. Sequences related to immune proteins in the mosquito Aedes aegypti
71. Involvement of sapecin in embryonic cell proliferation of Sarcophaga peregrina (flesh fly)
72. Synthesis of Sarcophaga lectin and sarcotoxins in NIH-Sape-4, an embryonic cell line of Sarcophaga peregrina
73. Molecular characterization of an insect transferrin and its selective incorporation into eggs during vitellogenesis
74. Mosquito cell culture
75. The cecropin locus in Drosophila: A compact gene cluster involved in the response to infection
76. Haemocyte behaviour
77. Small heat shock proteins distinguish between two mosquito species and confirm identity of their cell lines
78. Sequence analysis of a mosquito ribosomal protein rpL8 gene and its upstream regulatory region
79. New culture media for insect cells
80. Specification of Drosophila hematopoietic lineage by conserved transcription factors
81. Midgut-specific immune molecules are produced by the blood-sucking insect Stomoxys calcitrans
82. Defensins and protegrins: Vertebrate analogues of arthropod antimicrobial peptides
83. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
84. Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms
85. Polydnaviruses: Potent mediators of host insect immune dysfunction
86. Sharks and the origins of invertebrate immunity
87. Caterpillars have evolved lungs for hemocyte gas exchange
88. Iron economy in insects: Transport, metabolism and storage
89. Insect immunity: Isolation of three novel inducible antibacterial defensins from the vector mosquito. Aedes aegypti
90. Antimicrobial activity spectrum. cDNA cloning, and mRNA expression of a newly isolated member of the cecropin family from the mosquito vector Aedes aegypti
91. Insect immunity: Molecular cloning, expression and characterization of cDNAs and genomic DNA encoding three isoforms of insect defensin in Aedes aegypti
92. Methods for the development of cell lines from insects
93. Purification and characterization of ATBP, a novel protein that binds to A/T stretches in three segments of the Sarcophaga lectin gene
94. Purification of three antibacterial proteins from the culture medium of NIH-Sape-4, an embryonic cell line of Sarcophaga peregrina
95. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
96. A lysozyme in the salivary glands of the malaria vector Anopheles darlingi
97. A hemocyte-like cell line established from the malaria vector Anopheles gambiae expresses six prophenoloxidase genes
98. Retrieval of flanking DNA using a PCR-based approach with restriction enzyme-digested genomic DNA template
99. Revision of the genus Leptopilina Forster. 1869, with notes on the status of some other genera (Hymenoptera, Cynipoidea: Eucoilidae)
100. Cytokines and invertebrate immune responses
101. Growth of arboviruses in monolayers from subcultured mosquito embryo cells
102. Age dependence of salivary bacteriolytic activity in adult mosquitoes
103. Isolation and sequencing of three cecropins from the immune-competent Lepidoptera Estigmene acraea hemocyte line
104. Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking
105. Immunity to eukaryotic parasites in vector insects
106. Inducible immune factors of the vector mosquito Anopheles gambiae: Biochemical purification of a defensin antibacterial peptide and molecular cloning of a preprodefensin cDNA
107. Plasmodium activates the innate immune response of Anopheles gambiae mosquitoes
108. In vitro induction of cecropin genes - An immune response in a Drosophila blood cell line
109. The growth in vitro of single isolated cells
110. Sindbis virus-induced cytopathic effect in clones of Aedes albopictus (Singh) cells
111. Introduction
112. Studies on the propagation in vitro of poliomyelitis viruses. IV. Viral multiplication in a stable strain of human malignant epithelial cells (Strain HeLa) derived from an epidermoid carcinoma of the cervix
113. Humoral mediator-dependent activation of the Sarcophaga lectin gene
114. Cell cultures derived from larvae of Aedes albopictus (Skuse) and Aedes aegypti (L.)
115. Sequence and specificity of two antibacterial proteins involved in insect immunity
116. Lysozyme association with nucleic acids
117. Initiation and characterization of five embryonic cell lines from the cotton boll weevil Anthonomus grandis in a commercial serum-free medium
118. Characterization of monoclonal antibodies to hemocytes of Pseudoplusia includens
119. Peptide sequence of an antibiotic cecropin from the vector mosquito. Aedes albopictus
120. Cloning and expression of three cecropin cDNAs from a mosquito cell line
121. Cecropia immunoresponsive factor, an insect immunoresponsive factor with DNA-binding properties similar to nuclear-factor κB
122. Structure of two cecropin B-encoding genes and bacteria-inducible DNA-binding proteins which bind to the 5′ upstream regulatory region in the silkworm. Bombyx mori
123. Dominance of the CPE(+) phenotype in hybrid Aedes albopictus cells infected with Sindbis virus
124. Synthesis of immune proteins in primary cultures of fat body from Hyalophora cecropia
125. Phagocytosis: An overview
126. Cloning and analysis of a cecropin gene from the malaria vector mosquito. Anopheles gambiae
127. Fly development genes lead to immune find
128. Drosophila in cancer research: The first fifty tumor suppressor genes
129. Immunochemical identification of insect hemocyte populations: Monoclonal antibodies distinguish four major hemocyte types in Manduca sexta
130. LPS (lipopolysaccharide)-activated immune responses in a hemocyte cell line from Estigmene acraea (Lepidoptera)
131. Mosquito transferrin, an acute-phase protein that is up-regulated upon infection
132. Identification and characterization of the cecropin antibacterial protein gene locus in Drosophila virilis