Suicide gene therapy for premalignant disease: A new strategy for the treatment of intraepithelial neoplasia

Gene Therapy

Volumn 8, Issue 3, 2001, Pages 232-238

  Sandalon, Z ^a   Fusenig, N E ^b   Mccutcheon, J ^c   Taichman, L B ^a   Garlick, J A ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c NEW YORK UNIVERSITY   (United States)

Author keywords

Bystander effect; Cytosine deaminase; Organotypic culture; Premalignant disease; Suicide gene therapy

Indexed keywords

ANTINEOPLASTIC ANTIMETABOLITE; BACTERIAL ENZYME; BETA GALACTOSIDASE; CYTOSINE DEAMINASE; FLUCYTOSINE; FLUOROURACIL; PRODRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GENE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER MODEL; CANCER PREVENTION; CELL CONTACT; CELL KILLING; CONTROLLED STUDY; DEAMINATION; DOSE RESPONSE; DRUG ACTIVATION; DRUG POTENCY; DYSPLASIA; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; LD 50; MALE; MALIGNANT NEOPLASTIC DISEASE; MARKER GENE; MOUSE; NEWBORN; NONHUMAN; PRECANCER; PRIORITY JOURNAL; RECURRENT CANCER; SKIN CULTURE; SQUAMOUS CELL CARCINOMA; SUICIDE GENE; TRANSGENE; TREATMENT PLANNING;

ANTIMETABOLITES; CARCINOMA IN SITU; CELL CULTURE TECHNIQUES; CELL DEATH; CYTOSINE DEAMINASE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUCYTOSINE; GENE EXPRESSION; GENE THERAPY; HUMANS; INFANT, NEWBORN; KERATINOCYTES; MALE; MOUTH NEOPLASMS; NUCLEOSIDE DEAMINASES; PRECANCEROUS CONDITIONS; PRODRUGS;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0035110754     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301344     Document Type: Article

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