-
1
-
-
0027523517
-
A first step in the development of gene therapy for colorectal carcinoma: Cloning, sequencing, and expression of Escherichia coli cytosine deaminase
-
AUSTIN, E.A., and HUBER, B.E. (1993). A first step in the development of gene therapy for colorectal carcinoma: Cloning, sequencing, and expression of Escherichia coli cytosine deaminase. Mol. Pharmacol. 43, 380-387.
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 380-387
-
-
Austin, E.A.1
Huber, B.E.2
-
2
-
-
0004265596
-
-
John Wiley and Sons, New York
-
AUSUBEL, F.M., BRENT, R., KINGSTON, R.E., MOORE, D.D., SEIDMAN, J.G., SMITH, J.A., and STRUHL, K., eds. (1987). Current Protocols in Molecular Biology. (John Wiley and Sons, New York).
-
(1987)
Current Protocols in Molecular Biology
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
3
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
BRADFORD, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
4
-
-
0028989592
-
5-Fluorocytosine-induced eradication of murine adenocarcinomas engineered to express the cytosine deaminase suicide gene requires host immune competence and leaves an efficient memory
-
CONSALVO, M., MULLEN, C.A., MODESTI, A., MUSIANI, P., ALLIONE, A., CAVALLO, F., GIOVARELLI, M., and FORNI, G. (1995). 5-Fluorocytosine-induced eradication of murine adenocarcinomas engineered to express the cytosine deaminase suicide gene requires host immune competence and leaves an efficient memory. J. Immunol. 154, 5302-5312.
-
(1995)
J. Immunol.
, vol.154
, pp. 5302-5312
-
-
Consalvo, M.1
Mullen, C.A.2
Modesti, A.3
Musiani, P.4
Allione, A.5
Cavallo, F.6
Giovarelli, M.7
Forni, G.8
-
5
-
-
0026568864
-
Characterization of the Escherichia coli codBA operon encoding cytosine permease and cytosine deaminase
-
DANIELSEN, S., KILSTRUP, M., BARILLA, K., JOCHIMSEN, B., and NEUHARD, J. (1992). Characterization of the Escherichia coli codBA operon encoding cytosine permease and cytosine deaminase. Mol. Microbiol. 6, 1335-1344.
-
(1992)
Mol. Microbiol.
, vol.6
, pp. 1335-1344
-
-
Danielsen, S.1
Kilstrup, M.2
Barilla, K.3
Jochimsen, B.4
Neuhard, J.5
-
6
-
-
0024405257
-
Regulated expression of foreign genes in mammalian cells under the control of coliphage T3 RNA polymerase and lac repressor
-
DEUSCHLE, U., PEPPERKOK, R., WANG, F., GIORDANO, T.J., McALLISTER, W.T., ANSORGE, W., and BUJARD, H. (1989). Regulated expression of foreign genes in mammalian cells under the control of coliphage T3 RNA polymerase and lac repressor. Proc. Natl. Acad. Sci. USA 86, 5400-5404.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5400-5404
-
-
Deuschle, U.1
Pepperkok, R.2
Wang, F.3
Giordano, T.J.4
McAllister, W.T.5
Ansorge, W.6
Bujard, H.7
-
7
-
-
0029995247
-
In vivo replication-deficient adenovirus vector-mediated transduction of the cytosine deaminase gene sensitizes glioma cells to 5-fluorocytosine
-
DONG, Y., WEN, P., MANOME, Y., PARR, M., HIRSHOWITZ, A., CHEN, L., HIRSCHOWITZ, E.A., CRYSTAL, R., WEICHSELBAUM, R., KUFE, D.W., and FINE, H.A. (1996). In vivo replication-deficient adenovirus vector-mediated transduction of the cytosine deaminase gene sensitizes glioma cells to 5-fluorocytosine. Hum. Gene Ther. 7, 713-720.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 713-720
-
-
Dong, Y.1
Wen, P.2
Manome, Y.3
Parr, M.4
Hirshowitz, A.5
Chen, L.6
Hirschowitz, E.A.7
Crystal, R.8
Weichselbaum, R.9
Kufe, D.W.10
Fine, H.A.11
-
8
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
GOSSEN, M., and BUJARD, H. (1992). Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89, 5547-5551.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
10
-
-
0028426915
-
Gene therapy for cancer using tumour-specific prodrug activation
-
HARRIS, J.D., GUTIERREZ, A.A., HURST, H.C., SIKORA, K., and LEMOINE, N.R. (1994). Gene therapy for cancer using tumour-specific prodrug activation. Gene Ther. 1, 170-175.
-
(1994)
Gene Ther.
, vol.1
, pp. 170-175
-
-
Harris, J.D.1
Gutierrez, A.A.2
Hurst, H.C.3
Sikora, K.4
Lemoine, N.R.5
-
11
-
-
0028795075
-
In vivo adenovirus-mediated gene transfer of the Escherichia coli cytosine deaminase gene to human colon carcinoma-derived tumors induces chemosensitivity to 5-fluorocytosine
-
HIRSCHOWITZ, E.A., OHWADA, A., PASCAL, W.R., RUSSI, T.J., and CRYSTAL, R.G. (1995). In vivo adenovirus-mediated gene transfer of the Escherichia coli cytosine deaminase gene to human colon carcinoma-derived tumors induces chemosensitivity to 5-fluorocytosine. Hum. Gene Ther. 6, 1055-1063.
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 1055-1063
-
-
Hirschowitz, E.A.1
Ohwada, A.2
Pascal, W.R.3
Russi, T.J.4
Crystal, R.G.5
-
12
-
-
0023781763
-
Genetic approach to facilitate purification of recombinant proteins with a novel metal chelate adsorbent
-
HOCHULI, E., BANNWARTH, W., DÖBELI, H., GENTZ, R., and STÜBER, D. (1988). Genetic approach to facilitate purification of recombinant proteins with a novel metal chelate adsorbent. Bio/Technology 6, 1321-1325.
-
(1988)
Bio/Technology
, vol.6
, pp. 1321-1325
-
-
Hochuli, E.1
Bannwarth, W.2
Döbeli, H.3
Gentz, R.4
Stüber, D.5
-
13
-
-
0029923506
-
Comparison of the effects of three different toxin genes and their levels of expression on cell growth and bystander effect in lung adenocarcinoma
-
HOGANSON, D.K., BATRA, R.K., OLSEN, J.C., and BOUCHER, R.C. (1996). Comparison of the effects of three different toxin genes and their levels of expression on cell growth and bystander effect in lung adenocarcinoma. Cancer Res. 56, 1315-1323.
-
(1996)
Cancer Res.
, vol.56
, pp. 1315-1323
-
-
Hoganson, D.K.1
Batra, R.K.2
Olsen, J.C.3
Boucher, R.C.4
-
14
-
-
0027496518
-
In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase
-
HUBER, B.E., AUSTIN, E.A., GOOD, S.S., KNICK, V.C., TIBBELS, S., and RICHARDS, C.A. (1993). In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase. Cancer Res. 53, 4619-4626.
-
(1993)
Cancer Res.
, vol.53
, pp. 4619-4626
-
-
Huber, B.E.1
Austin, E.A.2
Good, S.S.3
Knick, V.C.4
Tibbels, S.5
Richards, C.A.6
-
15
-
-
0028108469
-
Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
-
HUBER, B.E., AUSTIN, E.A., RICHARDS, C.A., DAVIS, S.T., and GOOD, S.S. (1994). Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Proc. Natl. Acad. Sci. USA 91, 8302-8306.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8302-8306
-
-
Huber, B.E.1
Austin, E.A.2
Richards, C.A.3
Davis, S.T.4
Good, S.S.5
-
16
-
-
0018726056
-
A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines
-
KEARNEY, J.F., RADBRUCH, A., LIESEGANG, B., and RAJEWSKY, K. (1979). A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines. J. Immunol. 123, 1548-1550.
-
(1979)
J. Immunol.
, vol.123
, pp. 1548-1550
-
-
Kearney, J.F.1
Radbruch, A.2
Liesegang, B.3
Rajewsky, K.4
-
17
-
-
0027656118
-
Application of monoclonal antibodies against cytosine deaminase for the in vivo clearance of a cytosine deaminase immunoconjugate
-
KERR, D.E., GARRIGUES, U.S., WALLACE, P.M., HELLSTRÖM, K.E., HELLSTRÖM, I., and SENTER, P.D. (1993). Application of monoclonal antibodies against cytosine deaminase for the in vivo clearance of a cytosine deaminase immunoconjugate. Bioconjugate Chem. 4, 353-357.
-
(1993)
Bioconjugate Chem.
, vol.4
, pp. 353-357
-
-
Kerr, D.E.1
Garrigues, U.S.2
Wallace, P.M.3
Hellström, K.E.4
Hellström, I.5
Senter, P.D.6
-
18
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
LAEMMLI, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
19
-
-
0023376779
-
Pentapeptide nuclear localization signal in adenovirus E1a
-
LYONS, R.H., FERGUSON, B.Q., and ROSENBERG, M. (1987). Pentapeptide nuclear localization signal in adenovirus E1a. Mol. Cell. Biol. 7, 2451-2456.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 2451-2456
-
-
Lyons, R.H.1
Ferguson, B.Q.2
Rosenberg, M.3
-
20
-
-
0020521439
-
Characterization of BSp73, a spontaneous rat tumor and its in vivo selected variants showing different metastasizing capacities
-
MATZKU, S., KOMITOWSKI, D., MILDENBERGER, M., and ZÖLLER, M. (1983). Characterization of BSp73, a spontaneous rat tumor and its in vivo selected variants showing different metastasizing capacities. Invasion Metastasis 3, 109-123.
-
(1983)
Invasion Metastasis
, vol.3
, pp. 109-123
-
-
Matzku, S.1
Komitowski, D.2
Mildenberger, M.3
Zöller, M.4
-
21
-
-
0026599586
-
Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: A negative selection system
-
MULLEN, C.A., KILSTRUP, M., and BLAESE, R.M. (1992). Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: A negative selection system. Proc. Natl. Acad. Sci. USA 89, 33-37.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 33-37
-
-
Mullen, C.A.1
Kilstrup, M.2
Blaese, R.M.3
-
22
-
-
0028297316
-
Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor
-
MULLEN, C.A., COALE, M.M., LOWE, R., and BLAESE, R.M. (1994). Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor. Cancer Res. 54, 1503-1506.
-
(1994)
Cancer Res.
, vol.54
, pp. 1503-1506
-
-
Mullen, C.A.1
Coale, M.M.2
Lowe, R.3
Blaese, R.M.4
-
23
-
-
0029878461
-
Treatment of microscopic pulmonary metastases with recombinant autologous tumor vaccine expressing interleukin 6 and Escherichia coli cytosine deaminase suicide genes
-
MULLEN, C.A., PETROPOULOS, D., and LOWE, R.M. (1996). Treatment of microscopic pulmonary metastases with recombinant autologous tumor vaccine expressing interleukin 6 and Escherichia coli cytosine deaminase suicide genes. Cancer Res. 56, 1361-1366.
-
(1996)
Cancer Res.
, vol.56
, pp. 1361-1366
-
-
Mullen, C.A.1
Petropoulos, D.2
Lowe, R.M.3
-
24
-
-
0030052275
-
Cytosine deaminase gene as a potential tool for the genetic therapy of colorectal cancer
-
ROWLEY, S., LINDAUER, M., GEBERT, J.F., HABERKORN, U., OBERDORFER, F., MOEBIUS, U., HERFARTH, C., and SCHACKERT, H.-K. (1996). Cytosine deaminase gene as a potential tool for the genetic therapy of colorectal cancer. J. Surgical Oncol. 61, 42-48.
-
(1996)
J. Surgical Oncol.
, vol.61
, pp. 42-48
-
-
Rowley, S.1
Lindauer, M.2
Gebert, J.F.3
Haberkorn, U.4
Oberdorfer, F.5
Moebius, U.6
Herfarth, C.7
Schackert, H.-K.8
-
25
-
-
0003903343
-
-
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
-
SAMBROOK, J., FRITSCH, E.F., and MANIATIS, T., eds. (1989). Molecular Cloning: A Laboratory Manual. (Cold Spring Harbor Laboratory, Cold Spring Harbor, NY).
-
(1989)
Molecular Cloning: A Laboratory Manual
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
26
-
-
0025936459
-
lck and pp32, a possible common substrate
-
lck and pp32, a possible common substrate. Eur. J. Immunol. 21, 2469-2477.
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 2469-2477
-
-
Schraven, B.1
Kirchgessner, R.2
Gaber, B.3
Samstag, Y.4
Meuer, S.5
-
27
-
-
0026250463
-
Generation of 5-fluorouracil from 5-fluorocytosine by monoclonal antibody-cytosine deaminase conjugates
-
SENTER, P.D., SU, P.C.D., KATSURAGI, T., SAKAI, T., COSAND, W.L., HELLSTRÖM, I., and HELLSTRÖM, K.E. (1991). Generation of 5-fluorouracil from 5-fluorocytosine by monoclonal antibody-cytosine deaminase conjugates. Bioconjugate Chem. 2, 447-451.
-
(1991)
Bioconjugate Chem.
, vol.2
, pp. 447-451
-
-
Senter, P.D.1
Su, P.C.D.2
Katsuragi, T.3
Sakai, T.4
Cosand, W.L.5
Hellström, I.6
Hellström, K.E.7
-
28
-
-
0004214698
-
-
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
-
SILHAVY, T.J., BERMAN, M.L., and LYNN, W.E., eds. (1984). Experiments with Gene Fusions. (Cold Spring Harbor Laboratory, Cold Spring Harbor, NY).
-
(1984)
Experiments with Gene Fusions
-
-
Silhavy, T.J.1
Berman, M.L.2
Lynn, W.E.3
-
29
-
-
0028800141
-
Enzyme/prodrug gene therapy: Comparison of cytosine deaminase/5-fluorocytosine versus thymidine kinase/ganciclovir enzyme/prodrug systems in a human colorectal carcinoma cell line
-
TRINH, Q.T., AUSTIN, E.A., MURRAY, D.M., KNICK, V.C., and HUBER, B.E. (1995). Enzyme/prodrug gene therapy: Comparison of cytosine deaminase/5-fluorocytosine versus thymidine kinase/ganciclovir enzyme/prodrug systems in a human colorectal carcinoma cell line. Cancer Res. 55, 4808-4812.
-
(1995)
Cancer Res.
, vol.55
, pp. 4808-4812
-
-
Trinh, Q.T.1
Austin, E.A.2
Murray, D.M.3
Knick, V.C.4
Huber, B.E.5
-
30
-
-
0029122824
-
Detection of histidine-tagged fusion proteins by using a high-specific mouse monoclonal anti-histidine tag antibody
-
ZENTGRAF, H., FREY, M., SCHWINN, S., TESSMER, C., WILLEMANN, B., SAMSTAG, Y., and VELHAGEN, I. (1995). Detection of histidine-tagged fusion proteins by using a high-specific mouse monoclonal anti-histidine tag antibody. Nucleic Acids Res. 23, 3347-3348.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 3347-3348
-
-
Zentgraf, H.1
Frey, M.2
Schwinn, S.3
Tessmer, C.4
Willemann, B.5
Samstag, Y.6
Velhagen, I.7
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