12-O-tetradecanoylphorbol-13-acetate induces clonal expansion of potentially malignant keratinocytes in a tissue model of early neoplastic progression

Cancer Research

Volumn 59, Issue 2, 1999, Pages 474-481

  Karen, Jeffrey ^a   Wang, Youai ^a   Javaherian, Ashkan ^a   Vaccariello, Michael ^a   Fusenig, Norbert E ^c   Garlick, Jonathan A ^a,b  

^a STONY BROOK UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; FILAGGRIN; GROWTH PROMOTOR; KERATIN; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR PROMOTER;

ARTICLE; CANCER CELL; CONTROLLED STUDY; GROWTH RATE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; KERATINOCYTE; MALIGNANT TRANSFORMATION; NEWBORN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN CARCINOGENESIS; TUMOR GROWTH; TUMOR PROMOTION;

ANIMALS; CARCINOGENS; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; HUMANS; KERATINOCYTES; MICE; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE;

EID: 0033555615     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Yuspa, S.H. Chemical carcinogenesis related to the skin. Part 1. Progr. Dermatol., 15: 1-10, 1981
2. Yuspa, S. H., and Harris, C. C. Molecular and cellular basis of chemical carcinogenesis. In: Schottenfeld, D. and Fraumeni, J. F. (eds.), Cancer Epidemiology and Prevention. pp. 23-43. Philadelphia, PA: W. B. Saunders, 1982.
3. Yuspa, S. H., Ben, T., Hennings, H., and Lichti, U. Divergent responses in epidermal basal cells exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Cancer Res., 42: 2344-2349, 1982.
4. Jetten, A. M., George, M. A., Pettit, G. R., Herald, C. L., and Rearick, J. I. Action of phorbol esters, bryostatins, and retinoic acid on cholesterol sulfate synthesis: relation to the multistep process of differentiation in human epidermal keratinocytes. J. Invest. Dermatol., 93: 108-115, 1989.
5. Sharpe, G. R., Fisher, C., Gillespie, J. I., and Greenwell, J. R. Growth and differentiation stimuli induce different and distinct increases in intracellular free calcium in human keratinocyles. Arch. Dermatol. Res., 284: 445-450, 1993.
6. Yuspa, S. H., Hennings, H. Kulesz-Martin, M., and Lichti, U. The study of tumor promotion in a cell culture model for mouse skin - a tissue that exhibits multistage carcinogenesis in vivo. Carcinogenesis (Lond.), 7: 217-230, 1982.
7. Hennings, H., Lowry, D. T., Robinson, V. A., Morgan, D. L., Fujiki, H., and Yuspa, S. H. Activity of diverse tumor promoters in a keratinocyte co-culture model of initiated epidermis. Mol. Carcinog., 13: 2145-2151, 1992.
8. Hennings, H., Lowry, D. T., and Robinson, V. A. Coculture of neoplastic and normal keratinocytes as a model to study tumor promotion. Skin Pharmacol., 4: 79-84, 1991.
9. Javahcrian, A., Vaccariello, M., Fusenig, N. E., and Garlick, J. A. Normal keratinocytes suppress early stages of neoplastic progression in stratified epithelium. Cancer Res., 58: 2200-2208, 1998.
10. Boukamp, P., Stanbridge, E. J., Yin-Foo, D., Cerulti, P. A., and Fusenig, N. E. c-Ha-ras oncogene expression in immortalized human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy. Cancer Res., 50: 2840-2847, 1990.
11. H oncogene activation and additional chromosome loss. Oncogene. II: 961-969, 1995.
12. Rheinwald, J. G., and Green, H. Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinocyte colonies from single cells. Cell 6: 331-344, 1975.
13. Wu, Y-J., Parker, L. M., Binder, N. E., Beckett, M. A., Sinard, J. H., Griffiths, C. T., and Rheinwald, J. G. The mesothelial keratins: a new family of cytoskeletal proteins identified in cultured mesothelial cells nonkeratinizing epithelia. Cell. 31: 693-703, 1982.
14. Parenteau, N. L. Skin equivalents. In: I. M. Leigh and F. M. Watt (eds.). The Keratinocyte Handbook, pp. 45-56, Cambridge, United Kingdom: Cambridge University Press, 1994.
15. Dranoff, G., Jaffee, E., Lazenby, A., Golumbek, P., Levitsky, H., Brose, K., Jackson, V., Hamada, H., Pardoll, D., and Mulligan, R. C. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad. Sci. USA, 90: 3539-3543, 1993.
16. Garlick, J. A. 1994. Retroviral vectors. In: I. M. Leigh, E. B. Lane, and F. M. Watt (eds.), Keratinocyte Methods, pp. 181-183. Cambridge, United Kingdom: Cambridge University Press, 1994.
17. Yuspa, S. H. Chemical Carcinogenesis Related to the Skin. Part II. Evanston, Illinois: Dermatology Foundation pp. 1-16, 1982.
18. Hawley-Nelson, P., Stanley, J. R., Schmidt, J., Gullino, M., and Yuspa, S. H. The tumor promoter, 12-O-tetradecanoylphorbol-13-acetate, accelerates keratinocyte differentiation and stimulates growth of an unidentified cell type in cultured human epidermis. Exp. Cell Res., 137: 155-167, 1982.
19. Rice, R. H., Steinmann, K. E., deGraffenried, L. A., Qin, Q., Taylor, N., and Schlegel, R. Elevation of cell cycle control proteins during spontaneous immortalization of human keratinocyles. Mol. Biol. Cell. 4: 185-194, 1993.
20. Kalaoka, S., Naito, M., Fujita, N., Ishii, H., Yamori, T., Nakajima, M., and Tsuruo, T. Control of apoptosis and growth of malignant T lymphoma cells by lymph node stromal cells. Exp. Cell Res., 207: 271-276, 1993.
21. Bates, R. C., Buret, A., van Helden, D. F., Horton, M. A., and Burns, G. F. Apoptosis induced by inhibition of intercellular contact. J. Cell Biol., 125: 403-415, 1994.
22. Osgood, E. E. A unifying concept of the etiology of the leukemias, lymphomas, and cancers. J. Natl. Cancer Inst., 18: 155-166, 1957.
23. Bell, G. I. Models of carcinogenesis as an escape from mitolic inhibitors. Science (Washington DC), 192: 569-572, 1976.
24. Potter, V. Initiation and promotion in cancer formation: the importance of studies on intercellular communication. Yale J. Biol. Med., 53: 367-384, 1980.
25. Dotto, G. P., Parada, L. F., and Weinberg, R. A. Specific growth response of ras-transformed embryo fibroblasts to tumour promoters. Nature (Lond.), 318: 472-475, 1985.
26. Miki, H., Yamadori, I., Heine, U. I., Kenney, S., Riggs, C. W., and Rice, J. M. Effect of 12-O-tetradecanoylphorbol-13-acetate on intercellular communication in various clones of mouse epidermal JB6 cells. Cancer Res., 50: 1324-1329, 1990.
27. Yotti, L. P., Chang, C. C., and Trosko, J. E. Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter. Science (Washington DC), 206: 1089-1091, 1979.
28. Murray, A. W., and Fitzgerald, D. J. Tumor promoters inhibit metabolic cooperation in cocultures of epidermal and 3T3 cells. Biochem. Biophys. Res. Commun., 91: 395-401, 1979.