Antibiotic resistance in the absence of selective pressure

International Journal of Antimicrobial Agents

Volumn 17, Issue 3, 2001, Pages 171-176

  Gillespie, Stephen H ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Antibiotic resistance; Evolution; Multiple drug resistant tuberculosis; Selective pressure

Indexed keywords

ANTIBIOTIC AGENT; ETHAMBUTOL; ISONIAZID; PENICILLIN G; PYRAZINAMIDE; RIFAMPICIN; STREPTOMYCIN;

ADAPTATION; ANTIBIOTIC RESISTANCE; BACTERIAL INFECTION; BACTERIAL MUTATION; BACTERIAL VIRULENCE; EVOLUTION; FITNESS; HUMAN; IN VITRO STUDY; MULTIDRUG RESISTANCE; NATURAL SELECTION; NONHUMAN; PENICILLIN RESISTANCE; PRIORITY JOURNAL; REVIEW; TUBERCULOSIS;

EID: 0035101909     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(00)00340-X     Document Type: Article

References (50)

1. Genetic analysis of a plasmid-encoded, host genotype-specific enhancement of bacterial fitness
2. Transfer of erythromycin resistance from clinically isolated lysogenic strains of Streptococcus pyogenes via their endogenous phage
3. Emergence of vancomycin resistance in the genus Streptococcus: characterization of a vanB transferable determinant in Streptococcus bovis
4. Characterization of new mutations in pyrazinamide-resistant strains of Mycobacterium tuberculosis and identification of conserved regions important for the catalytic activity of the pyrazinamidase PncA
5. Molecular genetic basis of antimicrobial resistance in Mycobacterium tuberculosis: 1998 update
6. Antibiotic resistance in Streptococcus pneumoniae
7. Demonstration of homologous sequences between IS6110 and Mycrobacterium tuberculosis and other Mycobacterium spp.
8. Detection of rifampicin-resistance mutation in Mycobacterium tuberculosis
9. The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis
10. inhA a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis
11. Mycobacterium tuberculosis is a natural mutant with an inactivated stress regulatory gene: implications for sensitivity to isoniazid
12. Interactions of oxyR with the promoter region of oxyR and ahpC genes from Mycobacterium leprae and Mycobacterium tuberculosis
13. Mutations in PncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to the antituberculosis drug pyrazinamide in tubercle bacillus
14. Characterisation of the rpsL and rrs mutations in streptomycin resistant Mycobacterium tuberculosis isolates from diverse geographically localities
15. The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol
16. Characterization of fluoroquinolone-resistant strains of Mycobacterium tuberculosis selected in the laboratory and isolated from patients
17. Probability distribution of drug-resistant mutants in unselected populations of Mycobacterium tuberculosis
18. Acquisition of five high molecular weight penicillin binding protein variants during transfer of high level β-lactam resistance from Streptococcus mitis to Streptococcus pneumoniae
19. Mutations in PBP3 of a cefotaxime resistant laboratory mutant C604 and penicillin resistant clinical isolates of Streptococcus pneumoniae
20. Nucleotide sequence of penicillin binding protein 2b gene of Streptococcus pneumoniae
21. Biochemistry of the penicilloyl transferase
22. Genetics and molecular biology of β-lactam-resistant pneumococci
23. Alterations in kinetic properties of penicillin binding proteins of penicillin resistant Streptococcus pneumoniae
24. Altered peptidoglycan structure in a pneumococcal transformant resistant to penicillin
25. A biological price of antibiotic resistance: major changes in the peptidoglycan structure of penicillin resistant pneumococci
26. Evolution of a bacterial plasmid association
27. Adaptation to the fitness costs of antibiotic resistance in Escherichia coli
28. The physiological cost of rifampicin resistance induced in vitro in Mycobacterium tuberculosis
29. Tubercle bacilli resistant to isoniazid: virulence and response to treatment with isoniazid in guinea pigs and mice
30. Drug-resistant strains of Mycobacterium tuberculosis exhibit a range of virulence for mice
31. Effect of inhA and katG on isoniazid resistance and virulence in Mycobacterium bovis
32. The dynamic structure of EF-G studied by fusidic acid resistance and internal revertants
33. Novel ribosomal mutations affecting translational accuracy, antibiotic resistance and virulence of Salmonella typhimurium
34. Effect of environment on compensatory mutations to ameliorate the costs of antibiotic resistance
35. Experimental evolution of parasites
36. Tuberculosis: commentary on a reemergent killer
37. An outbreak of multi-drug-resistance tuberculosis in a London teaching hospital
38. Drug resistant tuberculosis in an urban population including patients at risk of human immunodeficiency virus infection
39. Identification of a W variant outbreak of Mycobacterium tuberculosis via population-based molecular epidemiology
40. A city wide outbreak of a multiple-drug resistant strain of Mycobacterium tuberculosis in New York
41. Comparison of fitness of two isolates of Mycobacterium tuberculosis, one of which had developed multi-drug resistance during the course of treatment
42. Induced resistance to penicillin of cultures of staphylococci, pneumococci, and streptococci
43. Susceptibility of pneumococci to nine antibiotics
44. A resistant pneumococcus
45. Pneumococci relatively insensitive to penicillin in Australia and New Guinea
46. Emergence of multiply resistant pneumococci
47. Penicillin-resistant Streptococcus pneumoniae
48. Transmission of multidrug resistant serotype 23F Streptococcus pneumoniae in group day care: evidence suggests capsular transformation of the resistant strain in vivo
49. Invasive pneumococcal disease in the immunocompromised