Augmented myocardial ischaemia by nicotine - Mechanisms and their possible significance

British Journal of Pharmacology

Volumn 125, Issue 1, 1998, Pages 79-86

  Schrör, Karsten ^a   Zimmermann, Katja C ^a   Tannhäuser, Roman ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

blocker; Catecholamines; COX 2 gene regulation; Prostacyclin

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CREATINE KINASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; MESSENGER RNA; NICOTINE; NORADRENALIN; PINDOLOL; PROSTACYCLIN; TROPONIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; GENE EXPRESSION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE ISCHEMIA; IMMUNOBLOTTING; ISOLATED HEART; MESSENGER RNA SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BIOLOGICAL MARKERS; CATECHOLAMINES; CYCLOOXYGENASE 2; EPOPROSTENOL; HEART; ISOENZYMES; MYOCARDIAL ISCHEMIA; MYOCARDIUM; NICOTINE; NOREPINEPHRINE; PINDOLOL; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0031689663     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702061     Document Type: Article

References (56)

1. BARBASH, G.I., WHITE, H.D., MODAN, M., DIAZ, R., HAMPTON, JR., HEIKKILA, J., KRISTINSSON, A., MOULOPOULOS, S., PAOLASSO, E.A., VAN DER WERF, T. et al. (1993). For the investigators of the international tissue plasminogen activator/ streptokinase mortality trial. Significance of smoking in patients receiving thrombolytic therapy for acute myocardial infarction. Circulation, 87, 53-58.
2. BOUNAMEAUX, H., GRIESSEN, M., BENEDET, P., KRAHENBUHL, B. & DEOM, A. (1998). Nicotine induced haemodynamic changes during cigarette smoking and nicotine gum chewing: A placebo-controlled study in young healthy volunteers. Cardiovasc. Res., 22, 154-158.
3. BOUTHERON-FALSON, O. & BLAES, N. (1990). Nicotine increases basal prostacyclin production and DNA synthesis of human endothelial cells in primary cultures. Nouv. Rev. Fr. Hematol., 32, 253-258.
4. BRADFORD, M. (1976). A rapid and sensitive method for the quantification of microgram quantities of protein using the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
5. BULL, H., PITTILO, R.M. & MACHIN, S.J. (1988). The effect of nicotine on human endothelial cell release of prostaglandins and ultrastructure. Br. J. Exp. Pathol., 69, 413-421.
6. CRYER, P.E., HAYMOND, M.W., SANTIAGO, J.V. & SHAH, S.D. (1976). Norepinepinephrine and epinephrine release and adrenergic mediation of smoking associated hemodynamic and metabolic events. N. Engl. J. Med., 295, 573-577.
7. DE CHILLOU, CH., RIFF, P., SADOUL, N., ÉTHEVENOT, G., FELDMANN, L., ISAAZ, K., SIMON, J.-PH., BOURSIER, M., KHALIFÈ, K., THISSE, J.-Y. & ALIOT, A. (1996). Influence of cigarette smoking on rate of reopening of the infarct-related coronary artery after myocardial infarction: A multivariate analysis. J. Am. Coll. Cardiol., 27, 1662-1668.
8. DOLL, R., PETO, R., WHEATLEY, K., GRAY, R. & SUTHERLAND, I. (1994). Mortality in relation to smoking: 40 years observation on male British doctors. Br. Med. J., 309, 901-911.
9. EHRENREICH, H., SCHUCK, J., STENDER, N., PILZ, J., GEFELLER, O., SCHILLING, L., POSER, W. & KAW, S. (1997). Endocrine and hemodynamic effects of stress versus systemic CRF in alcoholics during early and medium term abstinence. Alcohol Clin. Exp. Res., 21, 1285-1293.
10. EFFENEY, D.J. (1990). Effects of nicotine and carbon monoxide on prostacyclin production by the rabbit heart. Adv. Exp. Biol. Med., 273, 225-235.
11. FENG, L., SUN, W., XIA, Y., TANG, W.W., CHANMUGAM, P., SOYOOLA, E., WILSON, C.B. & HWANG, D. (1993). Cloning two isoforms of rat cyclooxygenase differential regulation of their expression. Arch. Biochem. Biophys., 307, 361-368.
12. GRINES, C.L., TOPOL, E.J., O'NEILL, W.W., GEORGE, B.S., KEREIAKES, D., PHILLIPS, H.R., LEIMBERGER, J.D., WOODLIEF, L.H. & CALIFF, R.M. (1995). Effect of cigarette smoking on outcome after thrombolytic therapy for myocardial infarction. Circulation, 91, 298-303.
13. GUSTO-1 INVESTIGATORS. (1995). Evaluation of paradox beneficial effects of smoking in patients receiving thrombolytic therapy for acute myocardial infarction: Mechanisms of the 'Smoker's Paradox' from the GUSTO-1 trial with angiographic insights. J. Am. Coll. Cardiol., 26, 1222-1229.
14. HEART AND STROKE FACTS. (1995). Statistical Supplement. Dallas TX: American Heart Association, 1994, 9-10.
15. HENNINGFIELD, J.E., STAPLETON, J.M., BENOWITZ, N.E., GRAYSON, R.F. & LONDON, E.D. (1993). Higher levels of nicotine in arterial than in venous blood after cigarette smoking. Drug Alcohol Depend., 33, 23-29.
16. HLA, T. & NEILSON, K. (1992). Human cyclooxygenase-2 cDNA. Proc. Natl. Acad. Sci. U.S.A., 89, 7384-7388.
17. HOEMGREN, S., ABRAHAMSSON, T., ALMGREN, O. & ERIKSSON, B.-M. (1981). Effect of ischaemia on the adrenergic neurons of the rat heart. A fluorescence histochemical and biochemical study. Cardiovasc. Res., 11, 680-689.
18. INOUE, H., YOKOYAMA, C., HARA, S., TONE, Y. & TANABE, T. (1995). Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. J. Biol. Chem., 270, 24965-24971.
19. KELEY, T.L., GILPIN, E., AHNVE, S., HENNING, H. & ROSS, J., JR. (1985). Smoking status at the lime of acute myocardial infarction and subsequent prognosis. Am. Heart J., 110, 535-541.
20. KOLBECK-RÜHMKORFF, C., HORBAN, A. & ZIMMER, H.-G. (1993). Effect of pressure and volume overload on proto-oncogene expression in the isolated working rat heart. Cardiovasc. Res., 27, 1998-2004.
21. KRÜGER, C., HAUNSTETTER, A., GERBER, ST., SERF, CH., KAUFMANN, A., KÜBLER, W. & HAASS, M (1995). Nicotine-induced exocytotic norepinephrine release in guinea-pig heart, human atrium and bovine adrenal chromaffin cells: modulation by single components of ischaemia. J. Mol. Cell. Cardiol., 27, 1491-1506.
22. LENNON, E.A., ANSELL, I., DAVIES, G.C. & POYSER, N.L. (1988). The effect of age and smoking on vascular prostaglandin production in men and women. Prostagl. Leukotr. Ess. Fatty Acids, 32, 15-21.
23. LOKKELHOLZ, K. (1979). Release induced by nicotinic agents. In The release of catecholamines from adrenergic neurons. ed. Paton, E.D. pp.275-301. Oxford: Pergamon Press.
24. MASDEN, R.R. & FLOWERS, N.C. (1980). Extension of experimental infarction with nicotine and estimates of infarct size. Am. Heart J., 99, 342-348.
25. MITCHELL, J.A., AKARASEREENONT, P., THIEMERMANM, C.H., FLOWER, R.J. & VANE, J.R. (1993). Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc. Natl. Acad. Sci. U.S.A., 90, 11693-11697.
26. MOLSTAD, P. (1991). First myocardial infarction in smokers. Eur. Heart J., 12, 753-759.
27. MUNTZ, K.H., HAGLER, H.K., WILLERSON, J.T. & BUJA, J.M. (1984). Redistribution of catecholamines in the ischemic zone of the dog heart. Am. J. Pathol., 114, 64-78.
28. NADLER, J.L. VELASO, J.S. & HORTON, R. (1983). Cigarette smoking inhibits prostacyclin formation. Lancet, 1, 1248-1250.
29. NOWAK, J., MURRAY, J.J., OATES, J.A. & FITZGERALD, G.A. (1987). Biochemical evidence of a chronic abnormality in platelet and vascular function in healthy individuals who smoke cigarettes. Circulation, 76, 6-14.
30. O'NEILL, G.P. & FORD-HUTCHINSON, A.W. (1993). Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett., 330, 156-160.
31. OTTO, J.C. & SMITH, W.L. (1995). Prostaglandin endoperoxide synthases-1 and -2. J. Lipid. Med., 12, 139-156.
32. QUILLEN, J.E., ROSSEN, J.D., OSKARSSON, H.J., MINOR, R.L., LOPEZ, A.G. & WINNIFORD, M.D. (1993). Acute effect of cigarette smoking on the coronary circulation: Constriction of epicardial and resistance vessels. J. Am. Coll. Cardiol., 22, 642-647.
33. RIUTTA, A., SAAREKS, V., MUCHA, L., ALANKO, J., PARVIAINEN, M. & VAPAATALO, H. (1995). Smoking cessation and nicotine substitution modulate eicosanoid synthesis ex vivo in man. Naunyn-Schmiedeberg's Arch. Pharmacol., 352, 102-107.
34. ROBINSON, K., CONROY, R.M. & MULCAHY, R. (1988). Smoking and acute coronary heart disease: a comparative study. Br. Heart J., 60, 465-469.
35. ROSE, J.E. (1996). Nicotine addiction and treatment. Annu. Rev. Med., 41, 493-507.
36. SCHÖMIG, A. (1990). Catecholamines in myocardial ischemia. Systemic and cardiac release. Circulation, 82 (suppl II), 1113-1122.
37. SCHÖMIG, A., DART, A.M., DIETZ, R., MAYER, K. & KÜBLER, W. (1984). Release of endogenous catecholamines in the ischemic myocardium of the rat. Part A: Locally mediated release. Circ. Res., 55, 689-701.
38. SCHÖMIG, A., FISCHER, S., KURZ, TH., RICHARDT, G. & SCHÖMIG, E. (1987). Nonexocytotic release of endogenous noradrenaline in the ischemic and anoxic rat heart: mechanism and metabolic requirements. Circ. Res., 60, 194-205.
39. 2 inhibits ischemia-induced platelet activation and prevents myocardial damage by inhibition of catecholamine release from adrenergic nerve terminals. Evidence for cAMP as common denominator. Thromb. Res., 21, 175-180.
40. 2 prevents ischemia-induced alterations in cardiac catecholamines without influencing nerve-stimulation-induced catecholamine release in nonischemic conditions. J. Cardiovasc. Pharmacol., 4, 741-748.
41. SCHRÖR, K. & FUNKE, K. (1985). Prostaglandins and myocardial noradrenaline overflow after sympathetic nerve stimulation during ischemia and reperfusion. J. Cardiovasc. Pharmacol., 7 (suppl 5), S50-S54.
42. SCHRÖR, K. & SEIDEL, H. (1988). Blood vessel arachidonate metabolism and its pharmacological modification in a new in vitro assay system. Naunyn-Schmiedeberg's Arch. Pharmacol., 337, 177-182.
43. SCHRÖR, K., OHLENDORF, R. & DARIUS, H. (1981b). Beneficial effects of a new prostacyclin derivative. ZK 36374, in acute myocardial ischemia. J Pharmacol. Exp. Ther., 219, 243-249.
44. SMEDES, K., KRAAK, J.C. & POPPE, H. (1982). Simple and fast solvent extraction system for selective and quantitative isolation of adrenaline, noradrenaline and dopamine from plasma and urine. J. Chromatography, 231, 25-39.
45. SRIDHARAN, M.R., FLOWERS, N.C., HAND, C., HAND, J.W. & HORAN, L.G. (1985). Effect of various regimens on chronic and acute nicotine exposure on myocardial infarct size in the dog. Am. J. Cardiol., 55, 1407-1411.
46. TIPPETTS, M.T,. VARNUM, B.C., LIM, R.W. & HERSCHMAN, H.R. (1988) Tumor promoter-inducible genes are differentially expressed in the developing mouse. Mol. Cell. Biol., 8, 4570-4572.
47. TOIVANEN, J., YLIKORKALA, O. & VIINIKA, L. (1986). Effects of smoking and nicotine on human prostacyclin and thromboxane production in vivo and in vitro. Toxicol. Appl. Pharmacol., 82, 301-306.
48. WENNMALM, A. (1977). Nicotine stimulates prostaglandin formation in the rabbit heart. Br. J. Pharmacol., 59, 95-100.
49. WENNMALM, A. (1978a). Effects of nicotine on cardiac prostaglandin and platelet thromboxane synthesis. Br. J. Pharmacol., 64, 559-563.
50. 1α, from the isolated perfused rabbit heart. Acta Physiol. Scand., 103, 107-109.
51. WeNNMALM, A. (1982). Interaction of nicotine and prostaglandins in the cardiovascular system. Prostaglandins, 23, 139-144.
52. WINNIFORD, M.D., WHEELAN, K.R., KREMERS, M.S., UGOLINI, V., VAN DEN BERG, E., JR, NIGGEMANN, E.H., JANSEN, D.E. & HILLIS, L.D. (1986). Smoking induced coronary vasoconstriction in patients with atherosclerotic coronary artery disease: evidence for adrenergically mediated alteration in coronary artery tone. Circulation, 73, 662-667.
53. WODITSCH, I. & SCHRÖR, K. (1992). Prostacyclin rather than endogenous nitric oxide is a tissue protective factor in myocardial ischemia. Am. J. Physiol., 263, H1390-H1396.
54. WU, K.K. (1995). Inducible cyclooxygenase and nitric oxide synthase. Adv. Pharmacol., 33, 179-207.
55. ZAHGER, D., CERCEK, B., CANNON, C.P., JORDAN, M., DAVIS, V., BRAUNWALD, E. & SHAH, P.K. FOR THE TIMI-4 INVESTIGATORS. (1995). How do smokers differ from nonsmokers in their response to thrombolysis? (The TIMI-4 Trial). Am. J. Cardiol., 75, 232-236.
56. ZHU. B., SUN, Y., SIEVERS, R.E., GLANTZ, S.A., PARMLEY, W.W. & WOLFE, C.L. (1994). Exposure to environmental tobacco smoke increases myocardial infarct size in rats. Circulation, 89, 1282-1290.