Pharmacokinetics of pefloxacin and its interaction with cyclosporin A, a P-glycoprotein modulator, in rat blood, brain and bile, using simultaneous microdialysis

British Journal of Pharmacology

Volumn 132, Issue 6, 2001, Pages 1310-1316

  Tsai, Tung Hu ^a,b  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Biliary excretion; Bloodbrain barrier; Cyclosporin A; Disposition; Microdialysis; P glycoprotein; Pefloxacin; Pharmacokinetics

Indexed keywords

CYCLOSPORIN A; GLYCOPROTEIN P; PEFLOXACIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BILIARY EXCRETION; BLOOD BRAIN BARRIER; DRUG BILE LEVEL; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; HEART RIGHT ATRIUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; JUGULAR VEIN; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0035083144     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703927     Document Type: Article

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