Effects of nicotinamide, an inhibitor of PARS activity, on gut and liver O2 exchange and energy metabolism during hyperdynamic porcine endotoxemia

Intensive Care Medicine

Volumn 27, Issue 3, 2001, Pages 586-592

  Theisen, M ^a   Trager K ^a   Tugtekin, I ^a   Georgieff, M ^a   Radermacher, P ^a   Matejovic M ^b  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Endotoxin; Gut; Lactate; Liver; Metabolism; PARS; Sepsis; Tonometry

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; ENZYME INHIBITOR; LACTIC ACID; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PYRUVIC ACID;

ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CARBON DIOXIDE TENSION; CONTROLLED STUDY; DRUG EFFECT; ENDOTOXEMIA; ENERGY METABOLISM; FEMALE; GAS EXCHANGE; HEART OUTPUT; HEMODYNAMICS; INTESTINE; INTESTINE PERFUSION; LIVER; LIVER PERFUSION; MALE; NONHUMAN; OXYGEN CONSUMPTION; SEPSIS; TONOMETRY;

ANIMALS; BLOOD GAS ANALYSIS; BLOOD PRESSURE; CARDIAC OUTPUT; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; ENDOTOXEMIA; ENERGY METABOLISM; FEMALE; HEMODYNAMIC PROCESSES; INTESTINES; LACTIC ACID; LIVER; MALE; NIACINAMIDE; OXYGEN CONSUMPTION; POLY(ADP-RIBOSE) POLYMERASES; PROSPECTIVE STUDIES; RANDOM ALLOCATION; SPLANCHNIC CIRCULATION; SWINE; TIME FACTORS;

EID: 0035079393     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340000842     Document Type: Article

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