Biochemical characterization of the FEZ-1 metallo-β-lactamase of Legionella gormanii ATCC 33297T produced in Escherichia coli

Antimicrobial Agents and Chemotherapy

Volumn 45, Issue 4, 2001, Pages 1254-1262

  Mercuri, P S ^a   Bouillenne, F ^a   Boschi, L ^a   Lamotte Brasseur, J ^a   Amicosante, G ^a   Devreese, B ^a   Van Beeumen, J ^a   Frere J M ^a   Rossolini, G M ^a   Galleni, M ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; AZTREONAM; BETA LACTAMASE; BIAPENEM; CARBENICILLIN; CEFALORIDINE; CEFALOTIN; CEFEPIME; CEFOTAXIME; CEFOXITIN; CEFPODOXIME; CEFUROXIME; CEPHALOSPORIN DERIVATIVE; CLAVULANIC ACID; CLOXACILLIN; GENE PRODUCT; IMIPENEM; LATAMOXEF; MEROPENEM; METALLO BETA LACTAMASE; MONOBACTAM DERIVATIVE; NITROCEFIN; PENICILLIN G; PIPERACILLIN; PROTEIN FEZ 1; TAZOBACTAM; TEMOCILLIN; TICARCILLIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZINC;

ARTICLE; BACTERIAL GENE; BINDING SITE; CHELATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG HYDROLYSIS; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME STRUCTURE; ESCHERICHIA COLI; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC CODE; LEGIONELLA; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; PRIORITY JOURNAL; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; BETA-LACTAMASES; BINDING SITES; CEPHALOSPORIN RESISTANCE; CHELATING AGENTS; ESCHERICHIA COLI; GENES, BACTERIAL; HYDROGEN-ION CONCENTRATION; KINETICS; LEGIONELLA; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION; ZINC;

EID: 0035077110     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.4.1254-1262.2001     Document Type: Article

References (41)

1. The structure of beta-lactamase
2. Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing β-lactamases in Chryseobacterium meningosepticum
3. The production and molecular properties of the zinc beta-lactamase of Pseudomonas maltophilia IID 1275
4. The Legionella (Fluoribacter) gormanii metallo-β-lactamase: A new member of the highly divergent lineage of molecular-subclass B3 β-lactamases
5. Unsual pH dependence of the class B β-lactamase-catalysed hydrolysis of substrates and their inhibition by thiols
6. A functional classification for β-lactamases and its correlation with molecular structure
7. The 3D structure of a zinc metallo-β-lactamase from Bacillus cereus reveals a new type of protein fold
8. Crystal structure of the wide-spectrum binuclear zinc β-lactamase from Bacteroides fragilis
9. Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: Binding determinants of a potent broad-spectrum inhibitor
10. Overexpression, purification, and characterization of the cloned metallo-β-lactamase L1 from Stenotrophomonas maltophilia
11. Automated analysis of enzyme inactivator phenomena
12. Crystal structure of the zinc-dependent beta-lactamase from Bacillus cereus at 1.9 Å resolution: Binuclear active site with features of a mononuclear enzyme
13. An overwiew of the kinetic parameter of class B β-lactamases
14. Kinetic analysis of extension of substrate specificity with Xanthomonas maltophilia, Aeromonas hydrophila, and Bacillus cereus metallo-β-lactamases
15. Biochemical properties of β-lactamase produced by Legionella gormanii
16. Standard numbering scheme for class B β-lactamases
17. Synthesis and SAR of thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase
18. Zn(II) dependence of the Aeromonas hydrophilia AE036 metallo β-lactamase activity and stability
19. Cloning and sequencing of the metallothioprotein β-lactamase II gene of Bacillus cereus 569H in Escherichia coli
20. Structure of In31, a blaIMP-containing Pseudomonas aeruginosa integron phyletically related to In5, which carries an unusual array of gene cassettes
21. Biochemical characterization of the Pseudomonas aeruginosa 101/1477 metallo β-lactamase IMP-1 produced by Escherichia coli
22. The Aeromonas hydrophila cphA gene: Molecular heterogeneity among class B metallo-β-lactamases
23. Kinetic mechanism of metallo-β-lactamase L1 from Stenotrophomonas maltophilia
24. Machine learning approaches for the prediction of signal peptides and other sorting signals
25. Molecular characterization of an enterobacterial metallo-β-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance
26. 2+-β-lactamase: Role of the conserved cysteine in the catalytic mechanism
27. Characterization of VIM-2, a carbapenem-hydrolyzing mctallo-β-lactamase and its plasmid- and integron-borne gene from a Pseudomonas aeruginosa clinical isolate in France
28. Interaction of cefotetan and the metallo beta-lactamases produced in Aeromonas spp. and in vitro activity
29. Carbapenem-hydrolyzing β-lactamases
30. Cloning and sequencing of the class B β-lactamase gene (ccrA) from Bacteroides fragilis TAL3636
31. IMP allele variants carried by gene cassettes of different phylogeny
32. Characterization and sequence of the Chryseobacterium (Flavobacterium) meningosepticum carbapenemase: A new molecular class B beta-lactamase showing a broad substrate profile
33. Molecular heterogeneity of the L-1 metallo β-lactamase family from Stenotrophomonas maltophilia
34. NMR characterization of the metallo-beta-lactamase from Bacteroides fragilis and its interaction with a tight-binding inhibitor: Role of an active-site loop
35. The crystal structure of the L1 metallo β-lactamase from Stenotromonas maltophilia at 1.7 Å resolution
36. Sequence and analysis of the L1 metallo-β-lactamase from Xanthomonas maltophilia
37. Nucleotide and amino acid sequences of the metallo-beta-lactamase, ImiS, from Aeromonas veronii by. sobria
38. Metallo β-lactamase: Structure and mechanism
39. On the mechanism of the metallo beta-lactamase from Bacteroides fragilis
40. Biochemical characterization of an imipenem-hydrolyzing metallo-β-lactamase from Bacteroides fragilis TAL3636