Cross-sectional study on cytokine polymorphisms, cytokine production after T-cell stimulation and clinical parameters in a random sample of a German population

Human Genetics

Volumn 108, Issue 3, 2001, Pages 241-248

  Nieters, A ^a   Brems, S ^a   Becker, N ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4 RECEPTOR; INTERLEUKIN 6; TUMOR NECROSIS FACTOR;

ADULT; ALLERGIC DISEASE; ARTICLE; CLINICAL EXAMINATION; COMMON COLD; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE ASSOCIATION; FEMALE; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENOTYPE; GERMANY; HAY FEVER; HEREDITY; HIGH RISK POPULATION; HOMOZYGOSITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PRIORITY JOURNAL; PROMOTER REGION; QUESTIONNAIRE; T LYMPHOCYTE ACTIVATION;

AGED; COHORT STUDIES; COMMON COLD; CROSS-SECTIONAL STUDIES; CYTOKINES; DNA; FEMALE; GENE FREQUENCY; GENOTYPE; GERMANY; HUMANS; HYPERSENSITIVITY; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-2; INTERLEUKIN-6; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; POLYMORPHISM, GENETIC; RANDOM ALLOCATION; RECEPTORS, INTERLEUKIN-4; SAMPLING STUDIES; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035074666     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390100464     Document Type: Article

References (37)

1. Association of polymorphisms within the tumour necrosis factor (TNF) genes and childhood asthma
2. Polymorphism of the human TNF-α promoter - Random variation or functional diversity?
3. Recent advances in the genetics of allergy and asthma
4. Association between an interleukin-6 promoter and 3′ flanking region haplotype and reduced Alzheimer's disease risk in a German population
5. Dense mapping of chromosome 12q13.12-q23.3 and linkage to asthma and atopy
6. Frequency of common colds and serum levels of sICAM-1 (CD54), sLFA-3 (CD58) and sIL-2R (CD25)
7. Epidemiologic investigation of serum levels of the soluble forms of CD25, CD54 and CD58, and T cell responsiveness after stimulation via the CD2-dependent pathway in a random sample of the general population
8. Th1/Th2 balance in atopy
9. Prevalence of tumor necrosis factor-alpha and angiotensin converting enzyme polymorphisms in mild/moderate and fatal/near-fatal asthma
10. Polymorphic haplotypes of the interleukin-10 5′ flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis
11. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis
12. On simultaneous confidence intervals for multinominal proportions
13. Evolving views of the major histocompatibility complex
14. The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor
15. Monoallelic expression of the interleukin-2 locus
16. Two novel polymorphisms in the IL-2 gene
17. Cytokine production by sinus lavage, bronchial lavage, and blood mononuclear cells in chronic rhinosinusitis with or without atopy
18. Reduced interferon gamma production by antigen-stimulated cord blood mononuclear cells is a risk factor of allergic disorders - 6-year follow-up study
19. Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases
20. Glutamine and tetrapepide repeat variations affect biological activity of different mouse interleukin-2 alleles
21. Allelic selection of human IL-2
22. The quantitative and qualitative defect of CD4+ CD45RO+ memory-type T cells are involved in the abnormality of TH1 immunity in atopic dermatitis patients
23. Tumour necrosis factor haplotypes and asthma
24. Extended tumour necrosis factor/HLA-DR haplotypes and asthma in an Australian population sample
25. Interleukin 4 receptor alpha chain polymorphism Gln551Arg is associated with adult atopic dermatitis in Japan
26. Analysis of single-nucleotide polymorphisms in the interleukin-4 receptor gene for association with inflammatory bowel disease
27. ARMS-PCR methodologies to determine IL-10, TNF-alpha, TNF-beta and TGF-beta 1 gene polymorphisms
28. In vitro production of IFN-gamma correlates with CA repeat polymorphism in the human IFN-gamma gene
29. Cytokines and immunity to viral infections
30. Nitric oxide inhibits rhinovirus-induced cytokine production and viral replication in a human respiratory epithelial cell line
31. Intercellular adhesion molecule-1 gene polymorphisms in Behçet's disease
32. Polymorphisms and linkage analysis for ICAM-1 and the selectin gene cluster
33. A genome-wide search for linkage to asthma. German asthma genetics group
34. Rhinovirus stimulation of interleukin-6 in vivo and in vitro. Evidence for nuclear factor kappa B-dependent transcriptional activation
35. Polymorphisms of the IL-4, TNF-alpha, and Fcepsilon RIbeta genes and the risk of allergic disorders in at-risk infants