Allelic selection of human IL-2 gene

European Journal of Immunology

Volumn 30, Issue 12, 2000, Pages 3516-3521

  Matesanz, Fuencisla ^a   Delgado, Concepcin ^b   Fresno, Manuel ^c   Alcina, Antonio ^a  

^a INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^b SAS   (Spain)

^c CSIC   (Spain)

Author keywords

Allelic exclusion; Gene regulation; Human IL 2; Single cell PCR; T lymphocyte

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2;

ALLELE; ARTICLE; CODON; EXON; GENE EXPRESSION REGULATION; GENE LOCUS; GENE SEQUENCE; GENETIC POLYMORPHISM; HETEROZYGOSITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE;

ALLELES; CD4-POSITIVE T-LYMPHOCYTES; CHROMOSOME MAPPING; HUMANS; INTERLEUKIN-2; TRANSCRIPTION, GENETIC;

EID: 0034536635     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(2000012)30:12<3516::AID-IMMU3516>3.0.CO;2-S     Document Type: Article

References (26)

1. Functional diversity of helper T lymphocytes
2. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
3. Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta
4. Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice
5. Absence of interleukin 2 production in a severe combined immunodeficiency disease syndrome with T cells
6. Transcriptional regulation of the IL-2 gene
7. Heterogeneity of single cell cytokine gene expression in clonal T cell populations
8. Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway
9. Chromatin remodeling of the interleukin-2 gene: Distinct alterations in the proximal versus distal enhancer regions
10. Monoallelic expression of the interleukin-2 locus
11. Mice with a fluorescent marker for interleukin 2 gene activation
12. Existence of at least five interleukin-2 molecules in different mouse strains
13. Lace of intermediate-affinity interleukin-2 receptor in mice leads to dependence on interleukin-2 receptor alpha, beta and gamma chain expression for T cell growth
14. Glutamine and tetrapeptide repeat variations affect the biological activity of different mouse interleukin-2 alleles
15. Structure of the human interleukin 2 gene
16. Allelic inactivation regulates olfactory receptor gene expression
17. Allele-specific gene expression in mammals: The curious case of the imprinted RNAs
18. Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu
19. Expansion of the allelic exclusion principle?
20. Suppressor factor of T-cell activation and decreased interleukin 2 activity in experimental African trypanosomiasis
21. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation
22. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-2 levels, and an association with systemic-onset of juvenile chronic arthritis
23. A polymorphism that affects oct-1 binding to TNF promoter region is associated with severe malaria
24. Two novel biallelic polymorphisms in the IL-2 gene
25. Interleukin-2 expression by a subpopulation of primary T cell is linked to enhanced memory/effector function
26. Regulation of IL-4 expression by activation of individual alleles