Differential effects of IH636 grape seed proanthocyanidin extract and a DNA repair modulator 4-aminobenzamide on liver microsomal cytochrome 4502E1-dependent aniline hydroxylation

Molecular and Cellular Biochemistry

Volumn 218, Issue 1-2, 2001, Pages 27-33

  Ray, S D ^a   Parikh, H ^a   Hickey, E ^a   Bagchi, M ^a   Bagchi, D ^a  

^a LONG ISLAND UNIVERSITY   (United States)

Author keywords

4 aminobenzamide (4 AB); Aniline hydroxylation; APAP (acetaminophen); Cytochrome P450 (P 450); Cytochrome P4502E1 (CYP 4502E1); IH636 grape seed proanthocyanidin extract (GSPE)

Indexed keywords

4 AMINOBENZAMIDE; ACETONE; ANILINE; CYTOCHROME P450 2E1; DNA; IH 636; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARACETAMOL; PLANT EXTRACT; PROANTHOCYANIDIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DIET; DNA REPAIR; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; GRAPE; HYDROXYLATION; IN VITRO STUDY; IN VIVO STUDY; LIVER MICROSOME; LIVER TOXICITY; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PLANT SEED; RAT;

4-AMINOBENZOIC ACID; ACETAMINOPHEN; ACETONE; ADMINISTRATION, ORAL; ANILINE COMPOUNDS; ANIMALS; BIOLOGICAL AVAILABILITY; CATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; CYTOPROTECTION; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; ISOENZYMES; MALE; MICE; MICE, INBRED STRAINS; MICROSOMES, LIVER; PLANT EXTRACTS; PROANTHOCYANIDINS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; VITIS SP.;

EID: 0035072449     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007272611915     Document Type: Article

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