Cellular and humoral immune response in progressive multifocal leukoencephalopathy

Annals of Neurology

Volumn 49, Issue 5, 2001, Pages 636-642

  Weber, Frank ^a,d   Goldmann, Claudia ^b   Krämer, Marcus ^b   Kaup, Franz Josef ^b   Pickhardt, Marcus ^c   Young, Peter ^c   Petry, Harald ^b   Weber, Thomas ^c   Lüke, Wolfgang ^b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b GERMAN PRIMATE CENTER   (Germany)

^c Marienkrankenhaus ^*

^d MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; ANTIRETROVIRUS AGENT; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 10; PHYTOHEMAGGLUTININ; TETANUS TOXOID; VIRUS DNA; VIRUS PROTEIN;

ARTICLE; CELL PROLIFERATION; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HELPER CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMORAL IMMUNITY; IMMUNE SYSTEM; JC VIRUS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; VIRUS LOAD;

CYTOKINES; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOGLOBULIN G; JC VIRUS; LEUKOCYTES, MONONUCLEAR; LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL; POLYMERASE CHAIN REACTION; VIRAL STRUCTURAL PROTEINS;

EID: 0035022771     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.1004     Document Type: Article

References (29)

1. Aström KE, Mancall EL, Richardson EP. Progressive multifocal leukoencephalopathy: a hitherto unrecognized complication of chronic lymphocytic leukemia and lymphoma. Brain 1958;81: 93-111.
2. Berger JR, Concha M. Progressive multifocal leukoencephalopathy: the evolution of a disease once considered rare. J Neurovirol 1995; 1:5-18.
3. Major EO, Ault GS. Progressive multifocal leukoencephalopathy: clinical and laboratory observations on a viral induced demyelinating disease in the immunodeficient patient. Curr Opin Neurol 1995;8:184-190.
4. Brooks BR, Walker DL. Progressive multifocal leukoencephalopathy. Neurol Clin 1984;2:299-313.
5. Bolton CF, Rozdilsky B. Primary progressive multifocal leukoencephalopathy. A case report. Neurology 1971;21:72-77.
6. Berger JR, Major EO. Progressive multifocal leukoencephalopathy. Semin Neurol 1999;19:193-200.
7. Weber T, Turner RW, Frye S, et al. Specific diagnosis of progressive multifocal leukoencephalopathy by polymerase chain reaction. J Infect Dis 1994;169:1138-1141.
8. Weber T, Trebst C, Frye S, et al. Analysis of the systemic and intrathecal humoral immune response in progressive multifocal leukoencephalopathy. J Infect Dis 1997;176:250-254.
9. Horn GV, Bastian FO, Moake JL. Progressive multifocal leukoencephalopathy: failure of response to transfer factor and cytarabine. Neurology 1978;28:794-797.
10. Willoughby E, Price RW, Padgett BL, et al. Progressive multifocal leukoencephalopathy (PML): in vitro cell-mediated immune responses to mitogens and JC virus. Neurology 1980;30: 256-262.
11. Goldmann C, Petry H, Frye S, et al. Molecular cloning and expression of the major structural protein VP1 of the human polyomavirus JC virus: formation of virus-like particles useful for immunological and therapeutic studies. J Virol 1999;73: 4465-4469.
12. Giudici B, Vaz B, Bossolasco S, et al. Highly active antiretroviral therapy and progressive multifocal leukoencephalopathy: effects on cerebrospinal fluid markers of JC virus replication and immune response. Clin Infect Dis 2000;30:95-99.
13. Whiteman ML, Post MJ, Berger JR, et al. Progressive multifocal leukoencephalopathy in 47 HIV-seropositive patients: neuroimaging with clinical and pathologic correlation. Radiology 1993;187:233-240.
14. Weber T, Major EO. Progressive multifocal leukoencephalopathy: molecular biology, pathogenesis and clinical impact. Intervirology 1997;40:98-111.
15. Ellison GW. Progressive multifocal leukoencephalopathy (PML). I. Investigation of the immunologic status of a patient with lymphosarcoma and PML. J Neuropathol Exp Neurol 1969;28:501-506.
16. Frye S, Trebst C, Dittmer U, et al. Efficient production of JC virus in SVG cells and the use of purified viral antigens for analysis of specific humoral and cellular immune response. J Virol Methods 1997;63:81-92.
17. Gallia GL, Houff SA, Major EO, Khalili K. JC virus infection of lymphocytes. J Infect Dis 1997;176:1603-1609.
18. Koralnik IJ, Boden D, Mai VX, et al. JC virus DNA load in patients with and without progressive multifocal leukoencephalopathy. Neurology 1999;52:253-260.
19. Estcourt MJ, Ramshaw IA, Ramsay AJ. Cytokine response in virus infections: effects on pathogenesis, recovery, and persistence. Curr Opin Microbiol 1998;1:411-418.
20. Clifford DB, Yiannoutsos C, Glicksman M, et al. HAART improves prognosis in HIV-associated progressive multifocal leukoencephalopathy. Neurology 1999;52:623-625.
21. Miralles P, Berenguer J, Garcia de Viedma D, et al. Treatment of AIDS-associated progressive multifocal leukoencephalopathy with highly active antiretroviral therapy. AIDS 1998;12:2467-2472.
22. Cinque P, Casari S, Bertelli D. Progressive multifocal leukoencephalopathy, HIV, and highly active antiretroviral therapy. N Engl J Med 1998;339:848-849.
23. Berger JR, Levy RM, Flomenhoft D, Dobbs M. Predictive factors for prolonged survival in acquired immunodeficiency syndrome-associated progressive multifocal leukoencephalopathy. Ann Neurol 1998;44:341-349.
24. Gasnault J, Taoufik Y, Goujard C, et al. Prolonged survival without neurological improvement in patients with AIDS-related progressive multifocal leukoencephalopathy on potent combined antiretroviral therapy. J Neurovirol 1999;5:421-429.
25. Chaisson RE, Gallant JE, Keruly JC, Moore RD. Impact of opportunistic disease on survival in patients with HIV infection. AIDS 1998;12:29-33.
26. Dworkin MS, Wan PC, Hanson DL, Jones JL. Progressive multifocal leukoencephalopathy: improved survival of human immunodeficiency virus-infected patients in the protease inhibitor era. J Infect Dis 1999;180:621-625.
27. Berger JR, Pall L, Lanska D, Whiteman M. Progressive multifocal leukoencephalopathy in patients with HIV infection. J Neurovirol 1998;4:59-68.
28. Szomolanyi-Tsuda E, Le QP, Garcea RL, Welsh RM. T-Cell-independent immunoglobulin G responses in vivo are elicited by live-virus infection but not by immunization with viral proteins or virus-like particles. J Virol 1998;72:6665-6670.
29. Szomolanyi-Tsuda E, Welsh RM. T-cell-independent antibody-mediated clearance of polyomavirus in T-cell-deficient mice. J Exp Med 1996;183:403-411.